Pembrolizumab plus axitinib versus sunitinib monotherapy as first-line treatment of advanced renal cell carcinoma (KEYNOTE-426): extended follow-up from a randomised, open-label, phase 3 trial
Powles, Thomas, Plimack, Elizabeth R, Soulières, Denis, Waddell, Tom, Stus, Viktor, Gafanov, Rustem, Nosov, Dmitry, Pouliot, Frédéric, Melichar, Bohuslav, Vynnychenko, Ihor, Azevedo, Sergio J, Borchiellini, Delphine, McDermott, Raymond S, Bedke, Jens, Tamada, Satoshi, Yin, Lina, Chen, Mei, Molife, L Rhoda, Atkins, Michael B, Rini, Brian I
Published in The lancet oncology (01.12.2020)
Published in The lancet oncology (01.12.2020)
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Journal Article
Cancer therapeutics: Targeting the apoptotic pathway
Khan, Khurum H, Blanco-Codesido, Montserrat, Molife, L. Rhoda
Published in Critical reviews in oncology/hematology (01.06.2014)
Published in Critical reviews in oncology/hematology (01.06.2014)
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Journal Article
Selective Inhibition of CYP17 With Abiraterone Acetate Is Highly Active in the Treatment of Castration-Resistant Prostate Cancer
Attard, Gerhardt, Reid, Alison H M, A'Hern, Roger, Parker, Christopher, Oommen, Nikhil Babu, Folkerd, Elizabeth, Messiou, Christina, Molife, L Rhoda, Maier, Gal, Thompson, Emilda, Olmos, David, Sinha, Rajesh, Lee, Gloria, Dowsett, Mitch, Kaye, Stan B, Dearnaley, David, Kheoh, Thian, Molina, Arturo, de Bono, Johann S
Published in Journal of clinical oncology (10.08.2009)
Published in Journal of clinical oncology (10.08.2009)
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Journal Article
Health-related Quality of Life Analysis from KEYNOTE-426: Pembrolizumab plus Axitinib Versus Sunitinib for Advanced Renal Cell Carcinoma
Bedke, Jens, Rini, Brian I., Plimack, Elizabeth R., Stus, Viktor, Gafanov, Rustem, Waddell, Tom, Nosov, Dimitry, Pouliot, Frederic, Soulières, Denis, Melichar, Bohuslav, Vynnychenko, Ihor, Azevedo, Sergio J., Borchiellini, Delphine, McDermott, Raymond S., Tamada, Satoshi, Nguyen, Allison Martin, Wan, Shuyan, Perini, Rodolfo F., Rhoda Molife, L., Atkins, Michael B., Powles, Thomas
Published in European urology (01.10.2022)
Published in European urology (01.10.2022)
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Corrigendum to "Pembrolizumab Plus Axitinib Versus Sunitinib as First-line Treatment of Advanced Renal Cell Carcinoma: 43-month Follow-up of the Phase 3 KEYNOTE-426 Study" [Eur Urol 84(5) (2023) 449-454]
Plimack, Elizabeth R, Powles, Thomas, Stus, Viktor, Gafanov, Rustem, Nosov, Dmitry, Waddell, Tom, Alekseev, Boris, Pouliot, Frédéric, Melichar, Bohuslav, Soulières, Denis, Borchiellini, Delphine, McDermott, Raymond S, Vynnychenko, Ihor, Chang, Yen-Hwa, Tamada, Satoshi, Atkins, Michael B, Li, Chenxiang, Perini, Rodolfo, Molife, L Rhoda, Bedke, Jens, Rini, Brian I
Published in European urology (01.11.2023)
Published in European urology (01.11.2023)
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Journal Article
Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate
Reid, Alison H M, Attard, Gerhardt, Danila, Daniel C, Oommen, Nikhil Babu, Olmos, David, Fong, Peter C, Molife, L Rhoda, Hunt, Joanne, Messiou, Christina, Parker, Christopher, Dearnaley, David, Swennenhuis, Joost F, Terstappen, Leon W M M, Lee, Gloria, Kheoh, Thian, Molina, Arturo, Ryan, Charles J, Small, Eric, Scher, Howard I, de Bono, Johann S
Published in Journal of clinical oncology (20.03.2010)
Published in Journal of clinical oncology (20.03.2010)
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Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort study
Olmos, David, MD, Postel-Vinay, Sophie, MD, Molife, L Rhoda, MD, Okuno, Scott H, MD, Schuetze, Scott M, MD, Paccagnella, M Luisa, PhD, Batzel, Gretchen N, MD, Yin, Donghua, PhD, Pritchard-Jones, Kathryn, Prof, Judson, Ian, Prof, Worden, Francis P, MD, Gualberto, Antonio, MD, Scurr, Michelle, MD, de Bono, Johann S, Dr, Haluska, Paul, MD
Published in The lancet oncology (01.02.2010)
Published in The lancet oncology (01.02.2010)
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Journal Article
Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers
Perkins, Geraldine, Yap, Timothy A, Pope, Lorna, Cassidy, Amy M, Dukes, Juliet P, Riisnaes, Ruth, Massard, Christophe, Cassier, Philippe A, Miranda, Susana, Clark, Jeremy, Denholm, Katie A, Thway, Khin, Gonzalez De Castro, David, Attard, Gerhardt, Molife, L Rhoda, Kaye, Stan B, Banerji, Udai, de Bono, Johann S
Published in PloS one (07.11.2012)
Published in PloS one (07.11.2012)
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Phase 1 dose-finding and pharmacokinetic study of eribulin-liposomal formulation in patients with solid tumours
Evans, T. R. Jeffry, Dean, Emma, Molife, L. Rhoda, Lopez, Juanita, Ranson, Malcolm, El-Khouly, Fatima, Zubairi, Ishtiaq, Savulsky, Claudio, Reyderman, Larisa, Jia, Yan, Sweeting, Lorna, Greystoke, Alastair, Barriuso, Jorge, Kristeleit, Rebecca
Published in British journal of cancer (19.02.2019)
Published in British journal of cancer (19.02.2019)
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Journal Article
Phase I Trials of Molecularly Targeted Agents: Should We Pay More Attention to Late Toxicities?
Postel-Vinay, Sophie, Gomez-Roca, Carlos, Molife, L Rhoda, Anghan, Bhavesh, Levy, Antonin, Judson, Ian, De Bono, Johann, Soria, Jean-Charles, Kaye, Stan, Paoletti, Xavier
Published in Journal of clinical oncology (01.05.2011)
Published in Journal of clinical oncology (01.05.2011)
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Journal Article
Phase 1/2a trial of intravenous BAL101553, a novel controller of the spindle assembly checkpoint, in advanced solid tumours
Kristeleit, Rebecca, Evans, Jeffry, Molife, L. Rhoda, Tunariu, Nina, Shaw, Heather, Slater, Sarah, Haris, Noor R. Md, Brown, Nicholas F., Forster, Martin D., Diamantis, Nikolaos, Rulach, Robert, Greystoke, Alastair, Asghar, Uzma, Rata, Mihaela, Anderson, Stephanie, Bachmann, Felix, Hannah, Alison, Kaindl, Thomas, Lane, Heidi A., Larger, Patrice J., Schmitt-Hoffmann, Anne, Engelhardt, Marc, Tzankov, Alexandar, Plummer, Ruth, Lopez, Juanita
Published in British journal of cancer (27.10.2020)
Published in British journal of cancer (27.10.2020)
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Phase I Dose Escalation Study of the Anti–Insulin-Like Growth Factor-I Receptor Monoclonal Antibody CP-751,871 in Patients with Refractory Solid Tumors
HALUSKA, Paul, SHAW, Heather M, ADJEI, Alex A, DE BONO, Johann S, BATZEL, Gretchen N, YIN, Donghua, MOLINA, Julian R, MOLIFE, L. Rhoda, YAP, Timothy A, ROBERTS, M. Luisa, SHARMA, Amarnath, GUALBERTO, Antonio
Published in Clinical cancer research (01.10.2007)
Published in Clinical cancer research (01.10.2007)
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Journal Article
Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-Label Studies
Dirix, Luc, MD, PhD, Swaisland, Helen, Verheul, Henk M.W., MD, PhD, Rottey, Sylvie, MD, PhD, Leunen, Karin, MD, Jerusalem, Guy, MD, PhD, Rolfo, Christian, MD, PhD, Nielsen, Dorte, MD, DMSc, Molife, L. Rhoda, BMedSci, BM BS, MRCP, MD, MSc, Kristeleit, Rebecca, BSc, MRCP, PhD, Vos-Geelen, Judith de, MD, PhD, Mau-Sørensen, Morten, MD, PhD, Soetekouw, Patricia, MD, van Herpen, Carla, MD, PhD, Fielding, Anitra, MBChB, So, Karen, MBBS, MRCS, MD, Bannister, Wendy, Plummer, Ruth, MD, D.Phil, FRCP
Published in Clinical therapeutics (01.10.2016)
Published in Clinical therapeutics (01.10.2016)
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Baseline clinical predictors of antitumor response to the PARP inhibitor olaparib in germline BRCA1/2 mutated patients with advanced ovarian cancer
Rafii, Saeed, Gourley, Charlie, Kumar, Rajiv, Geuna, Elena, Ern Ang, Joo, Rye, Tzyvia, Chen, Lee-May, Shapira-Frommer, Ronnie, Friedlander, Michael, Matulonis, Ursula, De Greve, Jacques, Oza, Amit M, Banerjee, Susana, Molife, L Rhoda, Gore, Martin E, Kaye, Stan B, Yap, Timothy A
Published in Oncotarget (18.07.2017)
Published in Oncotarget (18.07.2017)
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Journal Article
Belinostat: clinical applications in solid tumors and lymphoma
Molife, L Rhoda, de Bono, Johann S
Published in Expert opinion on investigational drugs (01.12.2011)
Published in Expert opinion on investigational drugs (01.12.2011)
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Journal Article
FGF Receptor Inhibitors: Role in Cancer Therapy
Daniele, Gennaro, Corral, Jesus, Molife, L. Rhoda, de Bono, Johann S.
Published in Current oncology reports (01.04.2012)
Published in Current oncology reports (01.04.2012)
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Journal Article
High frequency of radiological differential responses with poly(ADP-Ribose) polymerase (PARP) inhibitor therapy
Perez-Lopez, Raquel, Roda, Desam, Jimenez, Begona, Brown, Jessica, Mateo, Joaquin, Carreira, Suzanne, Lopez, Juanita, Banerji, Udai, Molife, L Rhoda, Koh, Dow-Mu, Kaye, Stan B, de Bono, Johann S, Tunariu, Nina, Yap, Timothy A
Published in Oncotarget (28.11.2017)
Published in Oncotarget (28.11.2017)
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Journal Article
Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors
Molife, L. Rhoda, Rudman, Sarah M., Alam, Salma, Tan, Daniel S.-W., Kristeleit, Hartmut, Middleton, Gary, Propper, David, Bent, Liz, Stopfer, Peter, Uttenreuther-Fischer, Martina, Wallenstein, Gudrun, de Bono, Johann, Spicer, James
Published in Cancer chemotherapy and pharmacology (01.12.2013)
Published in Cancer chemotherapy and pharmacology (01.12.2013)
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Journal Article
Phase I trials in patients with relapsed, advanced upper gastrointestinal carcinomas: experience in a specialist unit
Khan, Khurum, Ang, Joo Ern, Starling, Naureen, Sclafani, Francesco, Shah, Krunal, Judson, Ian, Molife, L. Rhoda, Banerji, Udai, de Bono, Johann S., Cunningham, David, Kaye, Stan B.
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.10.2014)
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01.10.2014)
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Journal Article
Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor
Barber, Louise J, Sandhu, Shahneen, Chen, Lina, Campbell, James, Kozarewa, Iwanka, Fenwick, Kerry, Assiotis, Ioannis, Rodrigues, Daniel Nava, Reis-Filho, Jorge S, Moreno, Victor, Mateo, Joaquin, Molife, L Rhoda, De Bono, Johann, Kaye, Stan, Lord, Christopher J, Ashworth, Alan
Published in The Journal of pathology (01.02.2013)
Published in The Journal of pathology (01.02.2013)
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