A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
Molenaars, Marte, Janssens, Georges E., Williams, Evan G., Jongejan, Aldo, Lan, Jiayi, Rabot, Sylvie, Joly, Fatima, Moerland, Perry D., Schomakers, Bauke V., Lezzerini, Marco, Liu, Yasmine J., McCormick, Mark A., Kennedy, Brian K., van Weeghel, Michel, van Kampen, Antoine H.C., Aebersold, Ruedi, MacInnes, Alyson W., Houtkooper, Riekelt H.
Published in Cell metabolism (03.03.2020)
Published in Cell metabolism (03.03.2020)
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Journal Article
Glycine promotes longevity in Caenorhabditis elegans in a methionine cycle-dependent fashion
Liu, Yasmine J, Janssens, Georges E, McIntyre, Rebecca L, Molenaars, Marte, Kamble, Rashmi, Gao, Arwen W, Jongejan, Aldo, Weeghel, Michel van, MacInnes, Alyson W, Houtkooper, Riekelt H
Published in PLoS genetics (07.03.2019)
Published in PLoS genetics (07.03.2019)
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Journal Article
Integrating the Hallmarks of Aging Throughout the Tree of Life: A Focus on Mitochondrial Dysfunction
van der Rijt, Sanne, Molenaars, Marte, McIntyre, Rebecca L, Janssens, Georges E, Houtkooper, Riekelt H
Published in Frontiers in cell and developmental biology (26.11.2020)
Published in Frontiers in cell and developmental biology (26.11.2020)
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Journal Article
Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4
McIntyre, Rebecca L., Molenaars, Marte, Schomakers, Bauke V., Gao, Arwen W., Kamble, Rashmi, Jongejan, Aldo, van Weeghel, Michel, van Kuilenburg, André B.P., Possemato, Richard, Houtkooper, Riekelt H., Janssens, Georges E.
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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Journal Article
ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, Garik V, Abdelmohsen, Kotb, Andreux, Pénélope, Bagdonaite, Ieva, Barzilai, Nir, Brunak, Søren, Cabreiro, Filipe, de Cabo, Rafael, Campisi, Judith, Cuervo, Ana Maria, Demaria, Marco, Ewald, Collin Y, Fang, Evandro Fei, Faragher, Richard, Ferrucci, Luigi, Freund, Adam, Silva-García, Carlos G, Georgievskaya, Anastasia, Gladyshev, Vadim N, Glass, David J, Gorbunova, Vera, de Grey, Aubrey, He, Wei-Wu, Hoeijmakers, Jan, Hoffmann, Eva, Horvath, Steve, Houtkooper, Riekelt H, Jensen, Majken K, Jensen, Martin Borch, Kane, Alice, Kassem, Moustapha, de Keizer, Peter, Kennedy, Brian, Karsenty, Gerard, Lamming, Dudley W, Lee, Kai-Fu, MacAulay, Nanna, Mamoshina, Polina, Mellon, Jim, Molenaars, Marte, Moskalev, Alexey, Mund, Andreas, Niedernhofer, Laura, Osborne, Brenna, Pak, Heidi H, Parkhitko, Andrey, Raimundo, Nuno, Rando, Thomas A, Rasmussen, Lene Juel, Reis, Carolina, Riedel, Christian G, Franco-Romero, Anais, Schumacher, Björn, Sinclair, David A, Suh, Yousin, Taub, Pam R, Toiber, Debra, Treebak, Jonas T, Valenzano, Dario Riccardo, Verdin, Eric, Vijg, Jan, Young, Sergey, Zhang, Lei, Bakula, Daniela, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Published in Aging (Albany, NY.) (30.12.2020)
Published in Aging (Albany, NY.) (30.12.2020)
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Journal Article
Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains
Gao, Arwen W., El Alam, Gaby, Lalou, Amélia, Li, Terytty Yang, Molenaars, Marte, Zhu, Yunyun, Overmyer, Katherine A., Shishkova, Evgenia, Hof, Kevin, Bou Sleiman, Maroun, Houtkooper, Riekelt H., Coon, Joshua J., Auwerx, Johan
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
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Journal Article
First person – Marte Molenaars and Bauke Schomakers
Published in Disease models & mechanisms
(01.04.2021)
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Journal Article
Mitochondrial cross-compartmental signalling to maintain proteostasis and longevity
Molenaars, Marte, Daniels, Eileen G, Meurs, Amber, Janssens, Georges E, Houtkooper, Riekelt H
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (22.06.2020)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (22.06.2020)
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Journal Article
Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity
McIntyre, Rebecca L., Denis, Simone W., Kamble, Rashmi, Molenaars, Marte, Petr, Michael, Schomakers, Bauke V., Rahman, Mizanur, Gupta, Siddhartha, Toth, Marton L., Vanapalli, Siva A., Jongejan, Aldo, Scheibye‐Knudsen, Morten, Houtkooper, Riekelt H., Janssens, Georges E.
Published in Aging cell (01.08.2021)
Published in Aging cell (01.08.2021)
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Journal Article
Metabolomics and lipidomics in Caenorhabditis elegans using a single-sample preparation
Molenaars, Marte, Schomakers, Bauke V, Elfrink, Hyung L, Gao, Arwen W, Vervaart, Martin A T, Pras-Raves, Mia L, Luyf, Angela C, Smith, Reuben L, Sterken, Mark G, Kammenga, Jan E, van Kampen, Antoine H C, Janssens, Georges E, Vaz, Frédéric M, van Weeghel, Michel, Houtkooper, Riekelt H
Published in Disease models & mechanisms (01.04.2021)
Published in Disease models & mechanisms (01.04.2021)
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Journal Article
A conserved complex lipid signature marks human muscle aging and responds to short-term exercise
Janssens, Georges E, Molenaars, Marte, Herzog, Katharina, Grevendonk, Lotte, Remie, Carlijn M E, Vervaart, Martin A T, Elfrink, Hyung L, Wever, Eric J M, Schomakers, Bauke V, Denis, Simone W, Waterham, Hans R, Pras-Raves, Mia L, van Weeghel, Michel, van Kampen, Antoine H C, Tammaro, Alessandra, Butter, Loes M, van der Rijt, Sanne, Florquin, Sandrine, Jongejan, Aldo, Moerland, Perry D, Hoeks, Joris, Schrauwen, Patrick, Vaz, Frédéric M, Houtkooper, Riekelt H
Published in Nature aging (01.05.2024)
Published in Nature aging (01.05.2024)
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Journal Article
Mitochondrial ubiquinone-mediated longevity is marked by reduced cytoplasmic mRNA translation
Molenaars, Marte, Janssens, Georges E, Santermans, Toon, Lezzerini, Marco, Jelier, Rob, MacInnes, Alyson W, Houtkooper, Riekelt H
Published in Life science alliance (31.08.2018)
Published in Life science alliance (31.08.2018)
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Journal Article
Acute inhibition of iron-sulfur cluster biosynthesis disrupts metabolic flexibility in mice
Molenaars, Marte, Mir, Hannan, Alvarez, Samantha W, Arivazhagan, Lakshmi, Rosselot, Carolina, Zhan, Di, Park, Christopher Y, Garcia-Ocana, Adolfo, Schmidt, Ann Marie, Possemato, Richard
Published in bioRxiv (19.08.2024)
Published in bioRxiv (19.08.2024)
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Journal Article
Multi-omics analysis identifies essential regulators of mitochondrial stress response in two wild-type C. elegans strains
Gao, Arwen W, Gaby El Alam, Lalou, Amelia, Terytty Yang Li, Molenaars, Marte, Zhu, Yunyun, Overmyer, Katherine A, Shishkova, Evgenia, Hof, Kevin, Maroun Samir Bou Sleiman, Houtkooper, Riekelt H, Coon, Joshua, Auwerx, Johan
Published in bioRxiv (20.07.2021)
Published in bioRxiv (20.07.2021)
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Paper
Metabolomics and lipidomics in C. elegans using a single sample preparation
Molenaars, Marte, Schomakers, Bauke V, Elfrink, Hyung L, Gao, Arwen W, Vervaart, Martin A T, Pras-Raves, Mia L, Luyf, Angela C, Smith, Reuben L, Sterken, Mark G, Kammenga, Jan E, Antoine H C Van Kampen, Janssens, Georges E, Vaz, Frédéric M, Michel Van Weeghel, Houtkooper, Riekelt H
Published in bioRxiv (06.07.2020)
Published in bioRxiv (06.07.2020)
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Paper