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Goodman, Aaron M, Kato, Shumei, Bazhenova, Lyudmila, Patel, Sandip P, Frampton, Garrett M, Miller, Vincent, Stephens, Philip J, Daniels, Gregory A, Kurzrock, Razelle
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Published in Molecular cancer therapeutics (01.11.2017)
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Matrix Metalloproteinase Inhibitors in Cancer Therapy: Turning Past Failures Into Future Successes
Winer, Arthur, Adams, Sylvia, Mignatti, Paolo
Published in Molecular cancer therapeutics (01.06.2018)
Published in Molecular cancer therapeutics (01.06.2018)
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Datopotamab Deruxtecan, a Novel TROP2-directed Antibody-drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells
Okajima, Daisuke, Yasuda, Satoru, Maejima, Takanori, Karibe, Tsuyoshi, Sakurai, Ken, Aida, Tetsuo, Toki, Tadashi, Yamaguchi, Junko, Kitamura, Michiko, Kamei, Reiko, Fujitani, Tomomichi, Honda, Tomoyo, Shibutani, Tomoko, Muramatsu, Sumie, Nakada, Takashi, Goto, Riki, Takahashi, Shu, Yamaguchi, Miki, Hamada, Hirofumi, Noguchi, Yutaka, Murakami, Masato, Abe, Yuki, Agatsuma, Toshinori
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Published in Molecular cancer therapeutics (01.12.2021)
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Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2 -deficient Mesothelioma
Tang, Tracy T, Konradi, Andrei W, Feng, Ying, Peng, Xiao, Ma, Mingyue, Li, Jian, Yu, Fa-Xing, Guan, Kun-Liang, Post, Leonard
Published in Molecular cancer therapeutics (01.06.2021)
Published in Molecular cancer therapeutics (01.06.2021)
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ATM Mutations in Cancer: Therapeutic Implications
Choi, Michael, Kipps, Thomas, Kurzrock, Razelle
Published in Molecular cancer therapeutics (01.08.2016)
Published in Molecular cancer therapeutics (01.08.2016)
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Antitumor activity of the glutaminase inhibitor CB-839 in triple-negative breast cancer
Gross, Matt I, Demo, Susan D, Dennison, Jennifer B, Chen, Lijing, Chernov-Rogan, Tania, Goyal, Bindu, Janes, Julie R, Laidig, Guy J, Lewis, Evan R, Li, Jim, Mackinnon, Andrew L, Parlati, Francesco, Rodriguez, Mirna L M, Shwonek, Peter J, Sjogren, Eric B, Stanton, Timothy F, Wang, Taotao, Yang, Jinfu, Zhao, Frances, Bennett, Mark K
Published in Molecular cancer therapeutics (01.04.2014)
Published in Molecular cancer therapeutics (01.04.2014)
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Preclinical Activity of HER2-Selective Tyrosine Kinase Inhibitor Tucatinib as a Single Agent or in Combination with Trastuzumab or Docetaxel in Solid Tumor Models
Kulukian, Anita, Lee, Patrice, Taylor, Janelle, Rosler, Robert, de Vries, Peter, Watson, Daniel, Forero-Torres, Andres, Peterson, Scott
Published in Molecular cancer therapeutics (01.04.2020)
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CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment
Fujiwara, Tomohiro, Yakoub, Mohamed A, Chandler, Andrew, Christ, Alexander B, Yang, Guangli, Ouerfelli, Ouathek, Rajasekhar, Vinagolu K, Yoshida, Aki, Kondo, Hiroya, Hata, Toshiaki, Tazawa, Hiroshi, Dogan, Yildirim, Moore, Malcolm A S, Fujiwara, Toshiyoshi, Ozaki, Toshifumi, Purdue, Ed, Healey, John H
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Published in Molecular cancer therapeutics (01.08.2021)
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Discovery and Pharmacological Characterization of JNJ-42756493 (Erdafitinib), a Functionally Selective Small-Molecule FGFR Family Inhibitor
Perera, Timothy P S, Jovcheva, Eleonora, Mevellec, Laurence, Vialard, Jorge, De Lange, Desiree, Verhulst, Tinne, Paulussen, Caroline, Van De Ven, Kelly, King, Peter, Freyne, Eddy, Rees, David C, Squires, Matthew, Saxty, Gordon, Page, Martin, Murray, Christopher W, Gilissen, Ron, Ward, George, Thompson, Neil T, Newell, David R, Cheng, Na, Xie, Liang, Yang, Jennifer, Platero, Suso J, Karkera, Jayaprakash D, Moy, Christopher, Angibaud, Patrick, Laquerre, Sylvie, Lorenzi, Matthew V
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Published in Molecular cancer therapeutics (01.06.2017)
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Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance
Chen, Ping, Lee, Nathan V, Hu, Wenyue, Xu, Meirong, Ferre, Rose Ann, Lam, Hieu, Bergqvist, Simon, Solowiej, James, Diehl, Wade, He, You-Ai, Yu, Xiu, Nagata, Asako, VanArsdale, Todd, Murray, Brion W
Published in Molecular cancer therapeutics (01.10.2016)
Published in Molecular cancer therapeutics (01.10.2016)
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Stereospecific PARP trapping by BMN 673 and comparison with olaparib and rucaparib
Murai, Junko, Huang, Shar-Yin N, Renaud, Amèlie, Zhang, Yiping, Ji, Jiuping, Takeda, Shunichi, Morris, Joel, Teicher, Beverly, Doroshow, James H, Pommier, Yves
Published in Molecular cancer therapeutics (01.02.2014)
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Plk1 Inhibitors in Cancer Therapy: From Laboratory to Clinics
Gutteridge, Rosie Elizabeth Ann, Ndiaye, Mary Ann, Liu, Xiaoqi, Ahmad, Nihal
Published in Molecular cancer therapeutics (01.07.2016)
Published in Molecular cancer therapeutics (01.07.2016)
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MALAT1 Is Associated with Poor Response to Oxaliplatin-Based Chemotherapy in Colorectal Cancer Patients and Promotes Chemoresistance through EZH2
Li, Peilong, Zhang, Xin, Wang, Haiyan, Wang, Lili, Liu, Tong, Du, Lutao, Yang, Yongmei, Wang, Chuanxin
Published in Molecular cancer therapeutics (01.04.2017)
Published in Molecular cancer therapeutics (01.04.2017)
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ARX788, a Site-specific Anti-HER2 Antibody–Drug Conjugate, Demonstrates Potent and Selective Activity in HER2-low and T-DM1–resistant Breast and Gastric Cancers
Skidmore, Lillian, Sakamuri, Sukumar, Knudsen, Nick A., Hewet, Amha Gebre, Milutinovic, Snezana, Barkho, Wisam, Biroc, Sandra Lyn, Kirtley, Jessica, Marsden, Robin, Storey, Kristine, Lopez, Ianina, Yu, Wayne, Fang, Shiao-Yan, Yao, Sulan, Gu, Yi, Tian, Feng
Published in Molecular cancer therapeutics (01.09.2020)
Published in Molecular cancer therapeutics (01.09.2020)
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The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models
Wengner, Antje M, Siemeister, Gerhard, Lücking, Ulrich, Lefranc, Julien, Wortmann, Lars, Lienau, Philip, Bader, Benjamin, Bömer, Ulf, Moosmayer, Dieter, Eberspächer, Uwe, Golfier, Sven, Schatz, Christoph A, Baumgart, Simon J, Haendler, Bernard, Lejeune, Pascale, Schlicker, Andreas, von Nussbaum, Franz, Brands, Michael, Ziegelbauer, Karl, Mumberg, Dominik
Published in Molecular cancer therapeutics (01.01.2020)
Published in Molecular cancer therapeutics (01.01.2020)
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A HER2-Targeting Antibody-Drug Conjugate, Trastuzumab Deruxtecan (DS-8201a), Enhances Antitumor Immunity in a Mouse Model
Iwata, Tomomi Nakayama, Ishii, Chiaki, Ishida, Saori, Ogitani, Yusuke, Wada, Teiji, Agatsuma, Toshinori
Published in Molecular cancer therapeutics (01.07.2018)
Published in Molecular cancer therapeutics (01.07.2018)
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