Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies
Moilanen, Anu-Maarit, Riikonen, Reetta, Oksala, Riikka, Ravanti, Laura, Aho, Eija, Wohlfahrt, Gerd, Nykänen, Pirjo S., Törmäkangas, Olli P., Palvimo, Jorma J., Kallio, Pekka J.
Published in Scientific reports (03.07.2015)
Published in Scientific reports (03.07.2015)
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Journal Article
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human α‐synuclein
Lakso, Merja, Vartiainen, Suvi, Moilanen, Anu‐Maarit, Sirviö, Jouni, Thomas, James H., Nass, Richard, Blakely, Randy D., Wong, Garry
Published in Journal of neurochemistry (01.07.2003)
Published in Journal of neurochemistry (01.07.2003)
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Journal Article
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity
Holmström, Tim H, Moilanen, Anu-Maarit, Ikonen, Tarja, Björkman, Mari L, Linnanen, Tero, Wohlfahrt, Gerd, Karlsson, Stefan, Oksala, Riikka, Korjamo, Timo, Samajdar, Susanta, Rajagopalan, Srinivasan, Chelur, Shekar, Narayanan, Kishore, Ramachandra, Raghuveer K, Mani, Jiju, Nair, Rashmi, Gowda, Nagaraj, Anthony, Thomas, Dhodheri, Samiulla, Mukherjee, Subhendu, Ujjinamatada, Ravi K, Srinivas, Nanduri, Ramachandra, Murali, Kallio, Pekka J
Published in Molecular cancer therapeutics (01.01.2019)
Published in Molecular cancer therapeutics (01.01.2019)
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Journal Article
Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors
Goswami, Rajeev, Mukherjee, Subhendu, Wohlfahrt, Gerd, Ghadiyaram, Chakshusmathi, Nagaraj, Jwala, Chandra, Beeram Ravi, Sistla, Ramesh K, Satyam, Leena K, Samiulla, Dodheri S, Moilanen, Anu, Subramanya, Hosahalli S, Ramachandra, Murali
Published in ACS medicinal chemistry letters (12.12.2013)
Published in ACS medicinal chemistry letters (12.12.2013)
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Journal Article
Identification of a Novel RING Finger Protein as a Coregulator in Steroid Receptor-Mediated Gene Transcription
Moilanen, Anu-Maarit, Poukka, Hetti, Karvonen, Ulla, Häkli, Marika, Jänne, Olli A., Palvimo, Jorma J.
Published in Molecular and Cellular Biology (01.09.1998)
Published in Molecular and Cellular Biology (01.09.1998)
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Journal Article
A Testis-specific Androgen Receptor Coregulator That Belongs to a Novel Family of Nuclear Proteins
Moilanen, Anu-Maarit, Karvonen, Ulla, Poukka, Hetti, Yan, Wei, Toppari, Jorma, Jänne, Olli A., Palvimo, Jorma J.
Published in The Journal of biological chemistry (05.02.1999)
Published in The Journal of biological chemistry (05.02.1999)
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Journal Article
Faulty Epithelial Polarity Genes and Cancer
Tervonen, Topi A., Partanen, Johanna I., Saarikoski, Sirkku T., Myllynen, Mikko, Marques, Elsa, Paasonen, Katriina, Moilanen, Anu, Wohlfahrt, Gerd, Kovanen, Panu E., Klefstrom, Juha
Published in Advances in Cancer Research (2011)
Published in Advances in Cancer Research (2011)
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Book Chapter
Journal Article
Activation of androgen receptor function by a novel nuclear protein kinase
Moilanen, A M, Karvonen, U, Poukka, H, Jänne, O A, Palvimo, J J
Published in Molecular biology of the cell (01.09.1998)
Published in Molecular biology of the cell (01.09.1998)
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Journal Article
Mutual Transcriptional Interference between RelA and Androgen Receptor
Palvimo, J J, Reinikainen, P, Ikonen, T, Kallio, P J, Moilanen, A, Jänne, O A
Published in The Journal of biological chemistry (27.09.1996)
Published in The Journal of biological chemistry (27.09.1996)
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Journal Article
Novel ATPase of SNF2-like protein family interacts with androgen receptor and modulates androgen-dependent transcription
Rouleau, Nathalie, Domans'kyi, Andrii, Reeben, Mati, Moilanen, Anu-Maarit, Havas, Kristina, Kang, Zhigang, Owen-Hughes, Tom, Palvimo, Jorma J, Jänne, Olli A
Published in Molecular biology of the cell (01.06.2002)
Published in Molecular biology of the cell (01.06.2002)
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Journal Article
Abstract 3827: Antitumor activity of ODM-207, a novel BET bromodomain inhibitor, in nonclinical models of ER+ breast cancer as single agent and as a combination treatment
Lindqvist, Julia, Björkman, Mari, Riikonen, Reetta, Nicorici, Daniel, Mattila, Elina, Jaleel, Mahaboobi, Abbineni, Chandrasekhar, Moilanen, Anu-Maarit
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Abstract 674: ODM-201 - New generation androgen receptor inhibitor targeting resistance mechanisms to androgen signalling-directed prostate cancer therapies
Moilanen, Anu-Maarit, Riikonen, Reetta, Kallio, Pekka J.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Journal Article
Abstract 3970: Therapeutic targeting of estrogen receptor positive breast cancer with the BET bromodomain inhibitor ODM-207
Lindqvist, Julia, Björkman, Mari, Riikonen, Reetta, Nicorici, Daniel, Mattila, Elina, Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Eriksson, John, Kallio, Pekka, Moilanen, Anu-Maarit
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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Journal Article
Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1
Oksala, Riikka, Moilanen, Anu, Riikonen, Reetta, Rummakko, Petteri, Karjalainen, Arja, Passiniemi, Mikko, Wohlfahrt, Gerd, Taavitsainen, Päivi, Malmström, Chira, Ramela, Meri, Metsänkylä, Hanna-Maija, Huhtaniemi, Riikka, Kallio, Pekka J., Mustonen, Mika VJ
Published in The Journal of steroid biochemistry and molecular biology (01.09.2019)
Published in The Journal of steroid biochemistry and molecular biology (01.09.2019)
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Journal Article
Abstract LB-113: Immune-mediated anti-tumor activity with a clinical stage BET bromodomain inhibitor ODM-207 in pre-clinical models
Deshpande, Pratima, Babu, Ravi Krishna, Vadnal, Prashant Yallappa, Jaleel, Mahaboobi, Ramachandra, Murali, Abbineni, Chandrasekhar, Samajdar, Susanta, Moilanen, Anu-Maarit, Kallio, Pekka
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1753: Targeting cancer with selective cbp/p300 bromodomain inhibitors
Jaleel, Mahaboobi, Senaiar, Ramesh S., Abbineni, Chandrasekhar, Renukappa, Girish A., Mukherjee, Subhendu, Marappan, Sivapriya, Samiulla, DS, Aravind, AB, Kumar, Naveen R., Reddy, Venkata Siva N., Babu, Asha, Srinivas, Akhila P., Yadlapalli, Prasad, Tgore, Suraj, NR, Raghavendra, Naik, Chandranath D., Giri, Sanjeev, Antony, Thomas, Nellore, Kavitha, Chelur, Shekar, Daginakatte, Girish, Ravanti, laura, Myllymäki, Mikko, Wohlfahrt, Gerd, Mattila, Elina, Karlsson, Stefan, Björkman, Mari, Riikonen, Reetta, Ikonen, Tarja, Leimu, Laura, Mälmström, Chira, Korjamo, Timo, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Abstract 1754: First in class orally bioavailable BETBRD degraders
Abbineni, Chandrasekhar, Jaleel, Mahaboobi, Mukherjee, Subhendu, Marappan, Sivapriya, Tiwari, Nirbhay Kumar, Samiulla, DS, Aravind, AB, Kumar, Naveen R, Bansal, Indu, Reddy, Raghurami B, Bandaru, NVM Rao, Srinivas, Akhila, Maben, Janith Mary, Tgore, Suraj, Kumar, Avainash, Nankar, Rakesh P., Naik, Chandranath D., Antony, Thomas, Nellore, Kavitha, Giri, Sanjeev, Daginakatte, Girish, Chelur, Shekar, Törmäkangas, Olli, Wohlfahrt, Gerd, Björkman, Mari, Mattila, Elina, Ravanti, Laura, Moilanen, Anu, Ramachandra, Murali, Samajdar, Susanta
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
ODM-204: A novel dual inhibitor of CYP17A1 and androgen receptor for the treatment of castration-resistant prostate cancer—Preclinical data
Oksala, Riikka, Moilanen, Anu, Riikonen, Reetta, Rummakko, Petteri, Huhtaniemi, Riikka, Kallio, Pekka
Published in Journal of clinical oncology (01.03.2015)
Published in Journal of clinical oncology (01.03.2015)
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Journal Article
Abstract 6179: Comparative study of Polθ helicase and polymerase inhibitor biochemical and cellular potency
Ahlskog, Johanna K., Pohjakallio, Antti, Paul, Ralf, Augustin, Martin, Schneider, Elisabeth, Johri, Sakshi, Tervahauta, Tuomas, Beisel, Hans-Georg, Neumann, Lars, Lindqvist, Julia, Moilanen, Anu
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article