Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists
Mohler, KM, Torrance, DS, Smith, CA, Goodwin, RG, Stremler, KE, Fung, VP, Madani, H, Widmer, MB
Published in The Journal of immunology (1950) (01.08.1993)
Published in The Journal of immunology (1950) (01.08.1993)
Get full text
Journal Article
Fully human CD19-specific chimeric antigen receptors for T-cell therapy
Sommermeyer, D, Hill, T, Shamah, S M, Salter, A I, Chen, Y, Mohler, K M, Riddell, S R
Published in Leukemia (01.10.2017)
Published in Leukemia (01.10.2017)
Get full text
Journal Article
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 2: SAR of the acetylenic P1' group
LEVIN, J. I, CHEN, J. M, MARCH, C. J, MOHLER, K. M, BLACK, R. A, SKOTNICKI, J. S, DU, M. T, NELSON, F. C, KILLAR, L. M, SKALA, S, SUNG, A, JIN, G, COWLING, R, BARONE, D
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Published in Bioorganic & medicinal chemistry letters (22.04.2002)
Get full text
Journal Article
Immune Function in Patients with Rheumatoid Arthritis Treated with Etanercept
Moreland, L.W., Bucy, R.P., Weinblatt, M.E., Mohler, K.M., Spencer-Green, G.T., Chatham, W.W.
Published in Clinical immunology (Orlando, Fla.) (01.04.2002)
Published in Clinical immunology (Orlando, Fla.) (01.04.2002)
Get full text
Journal Article
Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates
Levin, J.I., Chen, J.M., Cheung, K., Cole, D., Crago, C., Santos, E.Delos, Du, X., Khafizova, G., MacEwan, G., Niu, C., Salaski, E.J., Zask, A., Cummons, T., Sung, A., Xu, J., Zhang, Y., Xu, W., Ayral-Kaloustian, S., Jin, G., Cowling, R., Barone, D., Mohler, K.M., Black, R.A., Skotnicki, J.S.
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
Published in Bioorganic & medicinal chemistry letters (18.08.2003)
Get full text
Journal Article
Analysis of cytokine mRNA expression in the central nervous system of mice with experimental autoimmune encephalomyelitis reveals that IL-10 mRNA expression correlates with recovery
Kennedy, MK, Torrance, DS, Picha, KS, Mohler, KM
Published in The Journal of immunology (1950) (01.10.1992)
Published in The Journal of immunology (1950) (01.10.1992)
Get full text
Journal Article
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
Mohler, Kendall M, Sleath, Paul R, Fitzner, Jeffrey N, Cerretti, Douglas Pat, Alderson, Mark, Kerwar, Suresh S, Torranee, Dauphine S, Otten-Evans, Carol, Greenstreet, Teresa, Weerawarna, Kumudini, Kronheim, Shirley R, Petersen, Melissa, Gerhart, Mary, Kozlosky, Carl J, March, Carl J, Black, Roy A
Published in Nature (London) (21.07.1994)
Published in Nature (London) (21.07.1994)
Get full text
Journal Article
A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor
Mullberg, J, Durie, FH, Otten-Evans, C, Alderson, MR, Rose-John, S, Cosman, D, Black, RA, Mohler, KM
Published in The Journal of immunology (1950) (01.12.1995)
Published in The Journal of immunology (1950) (01.12.1995)
Get full text
Journal Article
Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors
Zask, A., Gu, Y., Albright, J.D., Du, X., Hogan, M., Levin, J.I., Chen, J.M., Killar, L.M., Sung, A., DiJoseph, J.F., Sharr, M.A., Roth, C.E., Skala, S., Jin, G., Cowling, R., Mohler, K.M., Barone, D., Black, R., March, C., Skotnicki, J.S.
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Published in Bioorganic & medicinal chemistry letters (17.04.2003)
Get full text
Journal Article
The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups
Levin, J I, Chen, J, Du, M, Hogan, M, Kincaid, S, Nelson, F C, Venkatesan, A M, Wehr, T, Zask, A, DiJoseph, J, Killar, L M, Skala, S, Sung, A, Sharr, M, Roth, C, Jin, G, Cowling, R, Mohler, K M, Black, R A, March, C J, Skotnicki, J S
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
Published in Bioorganic & medicinal chemistry letters (20.08.2001)
Get full text
Journal Article
The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines
Levin, J.I, Chen, J.M, Du, M.T, Nelson, F.C, Wehr, T, DiJoseph, J.F, Killar, L.M, Skala, S, Sung, A, Sharr, M.A, Roth, C.E, Jin, G, Cowling, R, Di, L, Sherman, M, Xu, Z.B, March, C.J, Mohler, K.M, Black, R.A, Skotnicki, J.S
Published in Bioorganic & medicinal chemistry letters (19.11.2001)
Published in Bioorganic & medicinal chemistry letters (19.11.2001)
Get full text
Journal Article
Induction of B cell costimulatory function by recombinant murine CD40 ligand
Kennedy, M K, Mohler, K M, Shanebeck, K D, Baum, P R, Picha, K S, Otten-Evans, C A, Janeway, Jr, C A, Grabstein, K H
Published in European journal of immunology (01.01.1994)
Published in European journal of immunology (01.01.1994)
Get more information
Journal Article
TNF Receptor-Deficient Mice Reveal Divergent Roles for p55 and p75 in Several Models of Inflammation
Peschon, Jacques J, Torrance, Dauphine S, Stocking, Kim L, Glaccum, Moira B, Otten, Carol, Willis, Cynthia R, Charrier, Keith, Morrissey, Philip J, Ware, Carol B, Mohler, Kendall M
Published in The Journal of immunology (1950) (15.01.1998)
Published in The Journal of immunology (1950) (15.01.1998)
Get full text
Journal Article
Evaluation of recombinant human soluble dimeric tumor necrosis factor receptor for prevention of OKT3-associated acute clinical syndrome
Eason, J D, Pascual, M, Wee, S, Farrell, M, Phelan, J, Boskovic, S, Blosch, C, Mohler, K M, Cosimi, A B
Published in Transplantation (27.01.1996)
Published in Transplantation (27.01.1996)
Get more information
Journal Article
Use of targeted anticytokine treatments in heart failure
Mohler, K M, Murray, K M, Mann, D L, Francis, G
Published in Circulation (New York, N.Y.) (29.08.2000)
Published in Circulation (New York, N.Y.) (29.08.2000)
Get full text
Journal Article
Identification of a distinct low-affinity receptor for human interleukin-4 on pre-B cells
FANSLOW, W. C, SPRIGGS, M. K, RAUCH, C. T, CLIFFORD, K. N, MACDUFF, B. M, ZIEGLER, S. F, SCHOOLEY, K. A, MOHLER, K. M, MARCH, C. J, ARMITAGE, R. J
Published in Blood (01.06.1993)
Published in Blood (01.06.1993)
Get full text
Journal Article