Development and Manufacturing GMP Scale-Up of a Continuous Ir-Catalyzed Homogeneous Reductive Amination Reaction
May, Scott A, Johnson, Martin D, Buser, Jonas Y, Campbell, Alison N, Frank, Scott A, Haeberle, Brian D, Hoffman, Philip C, Lambertus, Gordon R, McFarland, Adam D, Moher, Eric D, White, Timothy D, Hurley, D. Declan, Corrigan, Aoife P, Gowran, Olivia, Kerrigan, Niall G, Kissane, Marie G, Lynch, Regina R, Sheehan, Paul, Spencer, Richard D, Pulley, Shon R, Stout, James R
Published in Organic process research & development (18.11.2016)
Published in Organic process research & development (18.11.2016)
Get full text
Journal Article
Leveraging an Industrial–Academic Partnership To Optimize Small Molecule Process Development within the Pharmaceutical Industry
Deasy, Rebecca E, Slattery, Catherine N, Kissane, Marie, McNamara, Orla A, Lynch, Denis, Maguire, Anita R, Moynihan, Humphrey A, O’Keeffe, Sarah, Kopach, Michael E, Mitchell, David, Magnus, Nicholas A, Kjell, Douglas P, Moher, Eric D
Published in Organic process research & development (20.02.2015)
Published in Organic process research & development (20.02.2015)
Get full text
Journal Article
Catalytic Regioselective Sulfonylation of α-Chelatable Alcohols: Scope and Mechanistic Insight
Martinelli, Michael J, Vaidyanathan, Rajappa, Pawlak, Joseph M, Nayyar, Naresh K, Dhokte, Ulhas P, Doecke, Christopher W, Zollars, Lisa M. H, Moher, Eric D, Khau, Vien Van, Košmrlj, Berta
Published in Journal of the American Chemical Society (10.04.2002)
Published in Journal of the American Chemical Society (10.04.2002)
Get full text
Journal Article
Mechanistic investigation of a Ru-catalyzed direct asymmetric reductive amination reaction for a batch or continuous process scale-up: an industrial perspective
Changi, Shujauddin M., Yokozawa, Tohru, Yamamoto, Tetsuya, Nakajima, Hikaru, Embry, Matthew C., Vaid, Radhe, Luciani, Carla V., Wong, Sze-Wing, Johnson, Martin, Moher, Eric D.
Published in Reaction chemistry & engineering (01.10.2017)
Published in Reaction chemistry & engineering (01.10.2017)
Get full text
Journal Article
Process Development for a Key Synthetic Intermediate of LY2140023, a Clinical Candidate for the Treatment of Schizophrenia
Waser, Mario, Moher, Eric D., Borders, Sandy S. K., Hansen, Marvin M., Hoard, David W., Laurila, Michael E., LeTourneau, Michael E., Miller, Richard D., Phillips, Michael L., Sullivan, Kevin A., Ward, Jeffrey A., Xie, Chaoyu, Bye, Cheryl A., Leitner, Tanja, Herzog-Krimbacher, Brigitte, Kordian, Marcus, Müllner, Martin
Published in Organic process research & development (18.11.2011)
Published in Organic process research & development (18.11.2011)
Get full text
Journal Article
Dibutyltin Oxide Catalyzed Selective Sulfonylation of α-Chelatable Primary Alcohols
Martinelli, Michael J, Nayyar, Naresh K, Moher, Eric D, Dhokte, Ulhas P, Pawlak, Joseph M, Vaidyanathan, Rajappa
Published in Organic letters (12.08.1999)
Published in Organic letters (12.08.1999)
Get full text
Journal Article
Synthetic studies on quassinoids: total synthesis of simalikalactone D and assignment of the absolute configuration of the .alpha.-methylbutyrate ester side chain
Moher, Eric D, Collins, Jon L, Grieco, Paul A
Published in Journal of the American Chemical Society (01.03.1992)
Published in Journal of the American Chemical Society (01.03.1992)
Get full text
Journal Article
(R)-(+)- and (S)-(-)-5-Ethyl-5-methyl-1,3-dioxolane-2,4-dione reagents for the direct preparation of .alpha.-hydroxy-.alpha.-methylbutyrate esters: assignment of the absolute configuration of the .alpha.-acetoxy-.alpha.-methylbutyrate ester side chain of quassimarin via total synthesis
Moher, Eric D, Grieco, Paul A, Collins, Jon L
Published in Journal of organic chemistry (01.07.1993)
Published in Journal of organic chemistry (01.07.1993)
Get full text
Journal Article
Cryptophycins-309, 249 and other cryptophycin analogs: preclinical efficacy studies with mouse and human tumors
Liang, Jian, Moore, Richard E, Moher, Eric D, Munroe, John E, Al-awar, Rima S, Hay, David A, Varie, David L, Zhang, Tony Y, Aikins, James A, Martinelli, Michael J, Shih, Chuan, Ray, James E, Gibson, Lowell L, Vasudevan, Vasu, Polin, Lisa, White, Kathryn, Kushner, Juiwanna, Simpson, Chiab, Pugh, Susan, Corbett, Thomas H
Published in Investigational new drugs (01.06.2005)
Published in Investigational new drugs (01.06.2005)
Get full text
Journal Article
Design, Development, and Scale-Up of a Selective meso-Epoxide Desymmetrization Process
Varie, David L, Beck, Christopher, Borders, Sandra K, Brady, Molly D, Cronin, Jason S, Ditsworth, Tracy K, Hay, David A, Hoard, David W, Hoying, Richard C, Linder, Ryan J, Miller, Richard D, Moher, Eric D, Remacle, Jacob R, Rieck, John A, Anderson, David D, Dodson, Paul N, Forst, Mindy B, Pierson, Duane A, Turpin, Joseph A
Published in Organic process research & development (01.05.2007)
Published in Organic process research & development (01.05.2007)
Get full text
Journal Article
Synthesis of Cryptophycin 52 Using the Shi Epoxidation
Hoard, David W, Moher, Eric D, Martinelli, Michael J, Norman, Bryan H
Published in Organic letters (16.05.2002)
Published in Organic letters (16.05.2002)
Get full text
Journal Article
(2S,1‘S,2‘R,3‘R)-2-(2‘-Carboxy-3‘-hydroxymethylcyclopropyl) Glycine Is a Highly Potent Group 2 and 3 Metabotropic Glutamate Receptor Agonist with Oral Activity
Collado, Iván, Pedregal, Concepción, Bueno, Ana Belén, Marcos, Alicia, González, Rosario, Blanco-Urgoiti, Jaime, Pérez-Castells, Javier, Schoepp, Darryle D, Wright, Rebecca A, Johnson, Bryan G, Kingston, Ann E, Moher, Eric D, Hoard, David W, Griffey, Kelly I, Tizzano, Joseph P
Published in Journal of medicinal chemistry (15.01.2004)
Published in Journal of medicinal chemistry (15.01.2004)
Get full text
Journal Article
Synthesis of Unit A of Cryptophycin via a [2,3]-Wittig Rearrangement
Liang, Jian, Hoard, David W, Khau, Vien Van, Martinelli, Michael J, Moher, Eric D, Moore, Richard E, Tius, Marcus A
Published in Journal of organic chemistry (05.03.1999)
Published in Journal of organic chemistry (05.03.1999)
Get full text
Journal Article
Synthetic Studies on Quassinoids: Transformation of (−)-Glaucarubolone into (−)-Peninsularinone. In Vivo Antitumor Evaluation of (−)-Glaucarubolone, (−)-Chaparrinone, and (−)-Peninsularinone
Moher, Eric D, Reilly, Michael, Grieco, Paul A, Corbett, Thomas H, Valeriote, Frederick A
Published in Journal of organic chemistry (15.05.1998)
Published in Journal of organic chemistry (15.05.1998)
Get full text
Journal Article
ChemInform Abstract: Synthesis of Methyl 7,9-Dimethyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carboxylate and Its Analogues
Vaid, Radhe K., Boini, Sathish K., Alt, Charles A., Spitler, Jeremy T., Hadden, Chad E., Frank, Scott A., Moher, Eric D.
Published in ChemInform (01.03.2015)
Published in ChemInform (01.03.2015)
Get full text
Journal Article
Synthesis of Methyl 7,9-Dimethyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carboxylate and Its Analogues
Vaid, Radhe K., Boini, Sathish K., Alt, Charles A., Spitler, Jeremy T., Hadden, Chad E., Frank, Scott A., Moher, Eric D.
Published in Synthesis (Stuttgart) (15.09.2014)
Published in Synthesis (Stuttgart) (15.09.2014)
Get more information
Journal Article