TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
Balka, Katherine R., Louis, Cynthia, Saunders, Tahnee L., Smith, Amber M., Calleja, Dale J., D’Silva, Damian B., Moghaddas, Fiona, Tailler, Maximilien, Lawlor, Kate E., Zhan, Yifan, Burns, Christopher J., Wicks, Ian P., Miner, Jonathan J., Kile, Benjamin T., Masters, Seth L., De Nardo, Dominic
Published in Cell reports (Cambridge) (07.04.2020)
Published in Cell reports (Cambridge) (07.04.2020)
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Journal Article
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)–LRR oligomerization interface
Moghaddas, Fiona, Zeng, Ping, Zhang, Yuxia, Schützle, Heike, Brenner, Sebastian, Hofmann, Sigrun R., Berner, Reinhard, Zhao, Yuanbo, Lu, Bingtai, Chen, Xiaoyun, Zhang, Li, Cheng, Suyun, Winkler, Stefan, Lehmberg, Kai, Canna, Scott W., Czabotar, Peter E., Wicks, Ian P., De Nardo, Dominic, Hedrich, Christian M., Zeng, Huasong, Masters, Seth L.
Published in Journal of allergy and clinical immunology (01.12.2018)
Published in Journal of allergy and clinical immunology (01.12.2018)
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Journal Article
A Mutation Outside the Dimerization Domain Causing Atypical STING-Associated Vasculopathy With Onset in Infancy
Saldanha, Rohit G, Balka, Katherine R, Davidson, Sophia, Wainstein, Brynn K, Wong, Melanie, Macintosh, Rebecca, Loo, Christine K C, Weber, Martin A, Kamath, Vasanth, Moghaddas, Fiona, De Nardo, Dominic, Gray, Paul Edgar, Masters, Seth Lucian
Published in Frontiers in immunology (06.07.2018)
Published in Frontiers in immunology (06.07.2018)
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Journal Article
Recessive NLRC4-Autoinflammatory Disease Reveals an Ulcerative Colitis Locus
Steiner, Annemarie, Reygaerts, Thomas, Pontillo, Alessandra, Ceccherini, Isabella, Moecking, Jonas, Moghaddas, Fiona, Davidson, Sophia, Caroli, Francesco, Grossi, Alice, Castro, Fabio Fernandes Morato, Kalil, Jorge, Gohr, Florian N., Schmidt, Florian I., Bartok, Eva, Zillinger, Thomas, Hartmann, Gunther, Geyer, Matthias, Gattorno, Marco, Mendonça, Leonardo Oliveira, Masters, Seth L.
Published in Journal of clinical immunology (01.02.2022)
Published in Journal of clinical immunology (01.02.2022)
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Journal Article
Connexin-Dependent Transfer of cGAMP to Phagocytes Modulates Antiviral Responses
Pépin, Geneviève, De Nardo, Dominic, Rootes, Christina L, Ullah, Tomalika R, Al-Asmari, Sumaiah S, Balka, Katherine R, Li, Hong-Mei, Quinn, Kylie M, Moghaddas, Fiona, Chappaz, Stephane, Kile, Benjamin T, Morand, Eric F, Masters, Seth L, Stewart, Cameron R, Williams, Bryan R G, Gantier, Michael P
Published in mBio (28.01.2020)
Published in mBio (28.01.2020)
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Journal Article
COVID-19 vaccine allergy advice and guidance: The experience of a UK tertiary referral centre
Moghaddas, Fiona, Tsiougkos, Nikolaos, Grammatikos, Alexandros, Bright, Philip D., Johnston, Sarah, Gompels, Mark
Published in The World Allergy Organization journal (01.01.2023)
Published in The World Allergy Organization journal (01.01.2023)
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Journal Article
Blood group type A secretors are associated with a higher risk of COVID‐19 cardiovascular disease complications
Mankelow, Tosti J., Singleton, Belinda K., Moura, Pedro L., Stevens‐Hernandez, Christian J., Cogan, Nicola M., Gyorffy, Gyongyver, Kupzig, Sabine, Nichols, Luned, Asby, Claire, Pooley, Jennifer, Ruffino, Gabriella, Hosseini, Faroakh, Moghaddas, Fiona, Attwood, Marie, Noel, Alan, Cooper, Alex, Arnold, David T., Hamilton, Fergus, Hyams, Catherine, Finn, Adam, Toye, Ashley M., Anstee, David J.
Published in EJHaem (01.05.2021)
Published in EJHaem (01.05.2021)
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Journal Article
Web Resource
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK
Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Hill, Helen, Lazarus, Rajeka, Lawrie, Alison M, McGregor, Alastair, Villafana, Tonya L, Gilbert, Sarah C, Aban, Marites, Aboagye, Jeremy, Adam, Matthew, Adams, Kirsty, Alves, Mariana P.S., Barnes, Eleanor, Berrie, Eleanor, Bewley, Kevin R., Bletchly, Heather, Borthwick, Nicola, Brown, Phillip, Buttigieg, Karen R., Cashen, Paul, Castro, Lucia Carratala, Chadwick, Jim, Chapman, David, Charlton, Sue, Clark, Matthew, Clutterbuck, Elizabeth A., Cooper, Cushla, Cooper, Rachel, Darroch, Paula, Dearlove, David, Drake-Brockman, Rachael, van Eck, Samual, Farrar, Madi, Fraiman, Pedro H.A., Gracie, Lara, Grossi, Leonardo, Hanrath, Aidan T., Harris, Tara, Hassan, Shadin, Hay, Jodie, Head, Ian, Hodges, Gina, Horne, Elizea, Hou, Mimi M., Humphries, Holly E., Hyder-Wright, Angela, Jeffers, Helen, Karampatsas, Konstantinos, Keen, Jade, Khan, Liaquat, King, Thomas B., Klenerman, Paul, Lees, Emily A., Li, Yuanyuan, Loew, Lisa, Marques, Gabriela N., Masilela, Mduduzi, Mathew, Moncy, Meijs, Wilma, Morris, Susan, Mpelembue, Mushiya, Noal, Helena, Nugent, Fay L., O'Connor, Daniel, Olchawski, Victoria, O'Reilly, Paula, Phillips, Daniel J., Pickup, Lorinda, Du Plessis, Joan, Pollard, Samuel, Poulton, Ian, Pulido, David, Reiné, Jesús, Resuello-Dauti, Mila, Richter, Alex, Roche, Sophie, Rollier, Christine, Ruiz, Sarah, Sala, Claudia, Sanchez-Gonzalez, Amada, Sharpe, Hannah E., Smith, Daniel C., Smith, Holly E., Soares, Tiago, Souza, Cinthia M.C.D.L., Spina, Fernanda, Steven, Jill, Stockdale, Lisa, Stockwell, Lisa V., Sturdy, Ann, Tarr, Alexander W., Taylor, Ursula, Themistocleous, Andreas, Tsheko, Betty Lebogang, Turabi, Aadil, Waddington, Claire S., Wallis, Erica, Webb, Stewart
Published in The Lancet (British edition) (09.01.2021)
Published in The Lancet (British edition) (09.01.2021)
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Journal Article
Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials
Voysey, Merryn, Weckx, Lily Y, Collins, Andrea M, Feng, Shuo, Marshall, Richard P, Milan, Eveline P, Pollock, Katrina M, Ramasamy, Maheshi N, Robinson, Hannah, Andrade, Claudia Sala, Barker, Debbie, Bates, Louise, Batten, Alexander, Berzenyi, Daniella, Bird, Adam, Blundell, Susannah R., Budd, William, Cabrera Puig, Ingrid, Calvert, Anna, Carvalho, Yasmin de M., Castro, Thais R.Y., Chiplin, Emily, Cifuentes, Liliana, Danos, Zsofia, Dantas, Maria T.D.C., Davies, Sophie, Desai, Amisha, Drake-Brockman, Rachael, Edwards, Mandy, Edwards, Nick J., El Muhanna, Omar M., Ellison-Handley, Branwen, Fedosyuk, Sofiya, Fisher, Richard, Fofie, Hazel, Franco, Marilia M., Fuskova, Michelle, Godwin, Kerry, Gokani, Karishma, Gonçalves, Maria Luisa Freire, Goodall, Jack, Harris-Wright, Tara A., Howell, Nicola, Humphreys, Jonathan, Iyer, Vidyashankara, Jackson, Susan, Jaumdally, Shameem, Jorge, Marianna Rocha, Kellett Wright, Johanna, Kelly, Elizabeth J., Kelly, Dearbhla M., Kidd, Sarah, Larwood, Jessica P.J., Lees, Emily A., Lelliott, Alice, Leung, Stephanie, Manning, Nicola, Mazur, Olga, McGlashan, Joanna, Megson, Clare, Mesquita, Ana Carolina F., Mitton, Celia, Morrison, Hazel, Morselli, Franca, Oliveira, Catarina, Oosthuizen, Angela, Owen, David R.J., Parracho, Helena M. R.T., Perez, Ana Luiza, Perinpanathan, Tanaraj, Perumal, Rubeshan, Plank, Mary, Proud, Pamela C., Rajeswaran, Thurkka, Rees, Byron, Rhead, Sarah, Richards, Alexander, Roberts, Hannah, Robinson, Ryan E., Rudiansyah, Indra, Saunders, Jack E., Screaton, Gavin R., Sorley, Kim, Spencer, Alexandra J., Spoors, Louise, Stein, Ricardo, Strickland, Louise H., Sturdy, Ann, Sutton, Natalina, Taoushanis, Carol, Thomas, Merin, Tinoco, Lygia Accioly, Tomic, Adriana, Truby, Adam, Underwood, Benjamin R., Vichos, Iason, Watkins, Bridget, Wellbelove, Zoe, White, Caroline, Willingham, Silvia
Published in The Lancet (British edition) (06.03.2021)
Published in The Lancet (British edition) (06.03.2021)
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Journal Article
The incidence of physician‐diagnosed food allergy declines with age: A specialist UK centre experience
Grammatikos, Alexandros, Moghaddas, Fiona, White, Paul, Fox, Catherine, Johnston, Sarah, Tsiougkos, Nikolaos, Gompels, Mark
Published in Clinical and experimental allergy (01.02.2024)
Published in Clinical and experimental allergy (01.02.2024)
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Journal Article
Pyrin variant E148Q potentiates inflammasome activation and the effect of pathogenic mutations in cis
Reygaerts, Thomas, Laohamonthonkul, Pawat, Hrovat-Schaale, Katja, Moghaddas, Fiona, Baker, Paul J, Gray, Paul E, Masters, Seth L
Published in Rheumatology (Oxford, England) (01.03.2024)
Published in Rheumatology (Oxford, England) (01.03.2024)
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Journal Article
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever
Moghaddas, Fiona, Llamas, Rafael, De Nardo, Dominic, Martinez-Banaclocha, Helios, Martinez-Garcia, Juan J, Mesa-del-Castillo, Pablo, Baker, Paul J, Gargallo, Vanessa, Mensa-Vilaro, Anna, Canna, Scott, Wicks, Ian P, Pelegrin, Pablo, Arostegui, Juan I, Masters, Seth L
Published in Annals of the rheumatic diseases (01.12.2017)
Published in Annals of the rheumatic diseases (01.12.2017)
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Journal Article
The Salmonella pathogenicity island‐2 subverts human NLRP3 and NLRC4 inflammasome responses
Bierschenk, Damien, Monteleone, Mercedes, Moghaddas, Fiona, Baker, Paul J., Masters, Seth L., Boucher, Dave, Schroder, Kate
Published in Journal of leukocyte biology (01.02.2019)
Published in Journal of leukocyte biology (01.02.2019)
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Journal Article
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
Masters, Seth L, Lagou, Vasiliki, Jéru, Isabelle, Baker, Paul J, Van Eyck, Lien, Parry, David A, Lawless, Dylan, De Nardo, Dominic, Garcia-Perez, Josselyn E, Dagley, Laura F, Holley, Caroline L, Dooley, James, Moghaddas, Fiona, Pasciuto, Emanuela, Jeandel, Pierre-Yves, Sciot, Raf, Lyras, Dena, Webb, Andrew I, Nicholson, Sandra E, De Somer, Lien, van Nieuwenhove, Erika, Ruuth-Praz, Julia, Copin, Bruno, Cochet, Emmanuelle, Medlej-Hashim, Myrna, Megarbane, Andre, Schroder, Kate, Savic, Sinisa, Goris, An, Amselem, Serge, Wouters, Carine, Liston, Adrian
Published in Science translational medicine (30.03.2016)
Published in Science translational medicine (30.03.2016)
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Journal Article
Posttranslational Modification as a Critical Determinant of Cytoplasmic Innate Immune Recognition
Baker, Paul J, De Nardo, Dominic, Moghaddas, Fiona, Tran, Le Son, Bachem, Annabell, Nguyen, Tan, Hayman, Thomas, Tye, Hazel, Vince, James E, Bedoui, Sammy, Ferrero, Richard L, Masters, Seth L
Published in Physiological reviews (01.07.2017)
Published in Physiological reviews (01.07.2017)
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Journal Article
Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK
Shields, Adrian M, Anantharachagan, Ariharan, Arumugakani, Gururaj, Baker, Kenneth, Bahal, Sameer, Baxendale, Helen, Bermingham, William, Bhole, Malini, Boules, Evon, Bright, Philip, Chopra, Charu, Cliffe, Lucy, Cleave, Betsy, Dempster, John, Devlin, Lisa, Dhalla, Fatima, Diwakar, Lavanya, Drewe, Elizabeth, Duncan, Christopher, Dziadzio, Magdalena, Elcombe, Suzanne, Elkhalifa, Shuayb, Gennery, Andrew, Ghanta, Harichandrana, Goddard, Sarah, Grigoriadou, Sofia, Hackett, Scott, Hayman, Grant, Herriot, Richard, Herwadkar, Archana, Huissoon, Aarnoud, Jain, Rashmi, Jolles, Stephen, Johnston, Sarah, Khan, Sujoy, Laffan, James, Lane, Peter, Leeman, Lucy, Lowe, David M, Mahabir, Shanti, Lochlainn, Dylan James Mac, McDermott, Elizabeth, Misbah, Siraj, Moghaddas, Fiona, Morsi, Hadeil, Murng, Sai, Noorani, Sadia, O'Brien, Rachael, Patel, Smita, Price, Arthur, Rahman, Tasneem, Seneviratne, Suranjith, Shrimpton, Anna, Stroud, Catherine, Thomas, Moira, Townsend, Katie, Vaitla, Prashantha, Verma, Nisha, Williams, Anthony, Burns, Siobhan O, Savic, Sinisa, Richter, Alex G
Published in Clinical and experimental immunology (29.09.2022)
Published in Clinical and experimental immunology (29.09.2022)
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