Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O., Taylor, James G., Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Keller, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Use of Multiple Probes to Assess Transporter- and Cytochrome P450-Mediated Drug–Drug Interaction Potential of the Pangenotypic HCV NS5A Inhibitor Velpatasvir
Mogalian, Erik, German, Polina, Kearney, Brian P., Yang, Cheng Yong, Brainard, Diana, McNally, John, Moorehead, Lisa, Mathias, Anita
Published in Clinical pharmacokinetics (01.05.2016)
Published in Clinical pharmacokinetics (01.05.2016)
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Journal Article
Discovery of velpatasvir (GS-5816): A potent pan-genotypic HCV NS5A inhibitor in the single-tablet regimens Vosevi® and Epclusa
Link, John O., Taylor, James G., Trejo-Martin, Alejandra, Kato, Darryl, Katana, Ashley A., Krygowski, Evan S., Yang, Zheng-Yu, Zipfel, Sheila, Cottell, Jeromy J., Bacon, Elizabeth M., Tran, Chinh V., Yang, Cheng Y., Wang, Yujin, Wang, Kelly W., Zhao, Guangyu, Cheng, Guofeng, Tian, Yang, Gong, Ruoyu, Lee, Yu-Jen, Yu, Mei, Gorman, Eric, Mogalian, Erik, Perry, Jason K.
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
Published in Bioorganic & medicinal chemistry letters (15.08.2019)
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Population pharmacokinetics and exposure‐response analysis of a single dose of sotrovimab in the early treatment of patients with mild to moderate COVID‐19
Sager, Jennifer E., El‐Zailik, Asma, Passarell, Julie, Roepcke, Stefan, Li, Xiaobin, Aldinger, Melissa, Nader, Ahmed, Skingsley, Andrew, Alexander, Elizabeth L., Yeh, Wendy W., Mogalian, Erik, Garner, Chad, Peppercorn, Amanda, Shapiro, Adrienne E., Reyes, Maribel
Published in CPT: pharmacometrics and systems pharmacology (01.06.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2023)
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Journal Article
Correction to Discovery of Ledipasvir (GS-5885): A Potent, Once-Daily Oral NS5A Inhibitor for the Treatment of Hepatitis C Virus Infection
Link, John O, Taylor, James G, Xu, Lianhong, Mitchell, Michael, Guo, Hongyan, Liu, Hongtao, Kato, Darryl, Kirschberg, Thorsten, Sun, Jianyu, Squires, Neil, Parrish, Jay, Kellar, Terry, Yang, Zheng-Yu, Yang, Chris, Matles, Mike, Wang, Yujin, Wang, Kelly, Cheng, Guofeng, Tian, Yang, Mogalian, Erik, Mondou, Elsa, Cornpropst, Melanie, Perry, Jason, Desai, Manoj C
Published in Journal of medicinal chemistry (25.08.2016)
Published in Journal of medicinal chemistry (25.08.2016)
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Journal Article
Early Treatment for Covid-19 with SARS-CoV-2 Neutralizing Antibody Sotrovimab
Gupta, Anil, Gonzalez-Rojas, Yaneicy, Juarez, Erick, Crespo Casal, Manuel, Moya, Jaynier, Falci, Diego R, Sarkis, Elias, Solis, Joel, Zheng, Hanzhe, Scott, Nicola, Cathcart, Andrea L, Hebner, Christy M, Sager, Jennifer, Mogalian, Erik, Tipple, Craig, Peppercorn, Amanda, Alexander, Elizabeth, Pang, Phillip S, Free, Almena, Brinson, Cynthia, Aldinger, Melissa, Shapiro, Adrienne E
Published in New England Journal of Medicine (18.11.2021)
Published in New England Journal of Medicine (18.11.2021)
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Sofosbuvir and Velpatasvir for the Treatment of Hepatitis C Virus in Patients Coinfected With Human Immunodeficiency Virus Type 1: An Open-Label, Phase 3 Study
Wyles, David, Bräu, Norbert, Kottilil, Shyam, Daar, Eric S., Ruane, Peter, Workowski, Kimberly, Luetkemeyer, Anne, Adeyemi, Oluwatoyin, Kim, Arthur Y., Doehle, Brian, Huang, K. C., Mogalian, Erik, Osinusi, Anu, McNally, John, Brainard, Diana M., McHutchison, John G., Naggie, Susanna, Sulkowski, Mark
Published in Clinical infectious diseases (01.07.2017)
Published in Clinical infectious diseases (01.07.2017)
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A phase 1 study in healthy volunteers to investigate the safety, tolerability, and pharmacokinetics of VIR-2482: a monoclonal antibody for the prevention of severe influenza A illness
Plotnik, David, Sager, Jennifer E, Aryal, Madhukar, Fanget, Marie C, Peter, Alessia, Schmid, Michael A, Cebrik, Deborah, Mogalian, Erik, Boundy, Keith, Yeh, Wendy W, Griffin, Paul, Reyes, Maribel
Published in Antimicrobial agents and chemotherapy (03.04.2024)
Published in Antimicrobial agents and chemotherapy (03.04.2024)
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Journal Article
Drug-Drug Interaction Studies Between Hepatitis C Virus Antivirals Sofosbuvir/Velpatasvir and Boosted and Unboosted Human Immunodeficiency Virus Antiretroviral Regimens in Healthy Volunteers
Mogalian, Erik, Stamm, Luisa M, Osinusi, Anu, Brainard, Diana M, Shen, Gong, Ling, Kah Hiing John, Mathias, Anita
Published in Clinical infectious diseases (31.08.2018)
Published in Clinical infectious diseases (31.08.2018)
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Journal Article
Preclinical Pharmacokinetics and First-in-Human Pharmacokinetics, Safety, and Tolerability of Velpatasvir, a Pangenotypic Hepatitis C Virus NS5A Inhibitor, in Healthy Subjects
Mogalian, Erik, German, Polina, Kearney, Brian P, Yang, Cheng Yong, Brainard, Diana, Link, John, McNally, John, Han, LingLing, Ling, John, Mathias, Anita
Published in Antimicrobial agents and chemotherapy (01.05.2017)
Published in Antimicrobial agents and chemotherapy (01.05.2017)
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Journal Article
Sofosbuvir Plus Velpatasvir Combination Therapy for Treatment-Experienced Patients With Genotype 1 or 3 Hepatitis C Virus Infection: A Randomized Trial
Pianko, Stephen, Flamm, Steven L, Shiffman, Mitchell L, Kumar, Sonal, Strasser, Simone I, Dore, Gregory J, McNally, John, Brainard, Diana M, Han, Lingling, Doehle, Brian, Mogalian, Erik, McHutchison, John G, Rabinovitz, Mordechai, Towner, William J, Gane, Edward J, Stedman, Catherine A M, Reddy, K Rajender, Roberts, Stuart K
Published in Annals of internal medicine (01.12.2015)
Published in Annals of internal medicine (01.12.2015)
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Clinical and Preclinical Single-Dose Pharmacokinetics of VIR-2218, an RNAi Therapeutic Targeting HBV Infection
Gupta, Sneha V., Fanget, Marie C., MacLauchlin, Christopher, Clausen, Valerie A., Li, Jing, Cloutier, Daniel, Shen, Ling, Robbie, Gabriel J., Mogalian, Erik
Published in Drugs in R&D (01.12.2021)
Published in Drugs in R&D (01.12.2021)
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Journal Article
Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment
Mogalian, Erik, Brainard, Diana M., Osinusi, Anu, Moorehead, Lisa, Murray, Bernard, Ling, Kah Hiing John, Perry, Robert, Curtis, Craig, Lawitz, Eric, Lasseter, Kenneth, Marbury, Thomas, Mathias, Anita
Published in Clinical pharmacokinetics (01.11.2018)
Published in Clinical pharmacokinetics (01.11.2018)
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Journal Article
631. Preliminary safety and pharmacokinetic profile of VIR-2482: a monoclonal antibody for the prevention of influenza A illness
Sager, Jennifer, Hong, David K, Bonavia, Aurelio, Connolly, Lynn, Cebrik, Deborah, Fanget, Marie Christine, Mogalian, Erik, Griffin, Paul
Published in Open forum infectious diseases (31.12.2020)
Published in Open forum infectious diseases (31.12.2020)
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