Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer
Wei, Shuo, Kozono, Shingo, Kats, Lev, Nechama, Morris, Li, Wenzong, Guarnerio, Jlenia, Luo, Manli, You, Mi-Hyeon, Yao, Yandan, Kondo, Asami, Hu, Hai, Bozkurt, Gunes, Moerke, Nathan J, Cao, Shugeng, Reschke, Markus, Chen, Chun-Hau, Rego, Eduardo M, Lo-Coco, Francesco, Cantley, Lewis C, Lee, Tae Ho, Wu, Hao, Zhang, Yan, Pandolfi, Pier Paolo, Zhou, Xiao Zhen, Lu, Kun Ping
Published in Nature medicine (01.05.2015)
Published in Nature medicine (01.05.2015)
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Systematic analysis of BRAF(V600E) melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis
Fallahi-Sichani, Mohammad, Moerke, Nathan J, Niepel, Mario, Zhang, Tinghu, Gray, Nathanael S, Sorger, Peter K
Published in Molecular systems biology (26.03.2015)
Published in Molecular systems biology (26.03.2015)
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Understanding LRRK2 kinase activity in preclinical models and human subjects through quantitative analysis of LRRK2 and pT73 Rab10
Wang, Xiang, Negrou, Elvira, Maloney, Michael T., Bondar, Vitaliy V., Andrews, Shan V., Montalban, Manuel, Llapashtica, Ceyda, Maciuca, Romeo, Nguyen, Hoang, Solanoy, Hilda, Arguello, Annie, Przybyla, Laralynne, Moerke, Nathan J., Huntwork-Rodriguez, Sarah, Henry, Anastasia G.
Published in Scientific reports (18.06.2021)
Published in Scientific reports (18.06.2021)
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Small-Molecule Inhibition of the Interaction between the Translation Initiation Factors eIF4E and eIF4G
Moerke, Nathan J., Aktas, Huseyin, Chen, Han, Cantel, Sonia, Reibarkh, Mikhail Y., Fahmy, Amr, Gross, John D., Degterev, Alexei, Yuan, Junying, Chorev, Michael, Halperin, Jose A., Wagner, Gerhard
Published in Cell (26.01.2007)
Published in Cell (26.01.2007)
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Discovery of DNL343: A Potent, Selective, and Brain-Penetrant eIF2B Activator Designed for the Treatment of Neurodegenerative Diseases
Craig, Robert A., De Vicente, Javier, Estrada, Anthony A., Feng, Jianwen A., Lexa, Katrina W., Canet, Mark J., Dowdle, William E., Erickson, Rebecca I., Flores, Brittany N., Haddick, Patrick C. G., Kane, Lesley A., Lewcock, Joseph W., Moerke, Nathan J., Poda, Suresh B., Sweeney, Zachary, Takahashi, Ryan H., Tong, Vincent, Wang, Jing, Yulyaningsih, Ernie, Solanoy, Hilda, Scearce-Levie, Kimberly, Sanchez, Pascal E., Tang, Liwei, Xu, Musheng, Zhang, Rui, Osipov, Maksim
Published in Journal of medicinal chemistry (11.04.2024)
Published in Journal of medicinal chemistry (11.04.2024)
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Inhibition of the interactions between eukaryotic initiation factors 4E and 4G impairs long-term associative memory consolidation but not reconsolidation
Hoeffer, Charles A, Cowansage, Kiriana K, Arnold, Elizabeth C, Banko, Jessica L, Moerke, Nathan J, Rodriguez, Ricard, Schmidt, Enrico K, Klosi, Edvin, Chorev, Michael, Lloyd, Richard E, Pierre, Philippe, Wagner, Gerhard, LeDoux, Joseph E, Klann, Eric
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (22.02.2011)
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Assay Development and High-Throughput Screening for Inhibitors of Kaposi's Sarcoma-Associated Herpesvirus N-Terminal Latency-Associated Nuclear Antigen Binding to Nucleosomes
Beauchemin, Chantal, Moerke, Nathan J, Faloon, Patrick, Kaye, Kenneth M
Published in Journal of biomolecular screening (01.07.2014)
Published in Journal of biomolecular screening (01.07.2014)
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A high-throughput, cell-based screening method for siRNA and small molecule inhibitors of mTORC1 signaling using the In Cell Western technique
Hoffman, Gregory R, Moerke, Nathan J, Hsia, Max, Shamu, Caroline E, Blenis, John
Published in Assay and drug development technologies (01.04.2010)
Published in Assay and drug development technologies (01.04.2010)
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Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c‐Jun pathway in adaptive resistance to drug‐induced apoptosis
Fallahi‐Sichani, Mohammad, Moerke, Nathan J, Niepel, Mario, Zhang, Tinghu, Gray, Nathanael S, Sorger, Peter K
Published in Molecular systems biology (01.03.2015)
Published in Molecular systems biology (01.03.2015)
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Abstract 3744: Single-cell analysis of adaptive resistance and fractional responses of melanoma cells to RAF/MEK inhibition
Fallahi-Sichani, Mohammad, Moerke, Nathan J., Niepel, Mario, Zhang, Tnghu, Gray, Nathanael S., Sorger, Peter K.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Systematic analysis of BRAF V 600E melanomas reveals a role for JNK /c‐Jun pathway in adaptive resistance to drug‐induced apoptosis
Fallahi‐Sichani, Mohammad, Moerke, Nathan J, Niepel, Mario, Zhang, Tinghu, Gray, Nathanael S, Sorger, Peter K
Published in Molecular systems biology (01.03.2015)
Published in Molecular systems biology (01.03.2015)
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Development of in-cell Western assays using far-red fluorophores
Moerke, Nathan J, Hoffman, Gregory R
Published in Current protocols in chemical biology (01.03.2011)
Published in Current protocols in chemical biology (01.03.2011)
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Abstract 5213: A systems biology approach to understanding differential phenotypic outcome of BRAF(V600E) inhibition in melanoma cells
Fallahi-Sichani, Mohammad, Moerke, Nathan J., Dastur, Anahita, Benes, Cyril H., Sorger, Peter K.
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Differential determinants of cancer cell insensitivity to antimitotic drugs discriminated by a one-step cell imaging assay
Tang, Yangzhong, Xie, Tiao, Florian, Stefan, Moerke, Nathan, Shamu, Caroline, Benes, Cyril, Mitchison, Timothy J
Published in Journal of biomolecular screening (01.10.2013)
Published in Journal of biomolecular screening (01.10.2013)
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Reverse Phase Protein Arrays for Compound Profiling
Moerke, Nathan, Fallahi-Sichani, Mohammad
Published in Current protocols in chemical biology (13.09.2016)
Published in Current protocols in chemical biology (13.09.2016)
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Synthesis of fluorescein labeled 7-methylguanosinemonophosphate
Natarajan, Amarnath, Moerke, Nathan, Fan, Yun-Hua, Chen, Han, Christ, William J., Wagner, Gerhard, Halperin, Jose A.
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
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