Vaginal pH measured in vivo: lactobacilli determine pH and lactic acid concentration
O'Hanlon, Deirdre Elizabeth, Come, Richard A, Moench, Thomas R
Published in BMC microbiology (14.01.2019)
Published in BMC microbiology (14.01.2019)
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The cervicovaginal mucus barrier to HIV-1 is diminished in bacterial vaginosis
Hoang, Thuy, Toler, Emily, DeLong, Kevin, Mafunda, Nomfuneko A, Bloom, Seth M, Zierden, Hannah C, Moench, Thomas R, Coleman, Jenell S, Hanes, Justin, Kwon, Douglas S, Lai, Samuel K, Cone, Richard A, Ensign, Laura M
Published in PLoS pathogens (01.01.2020)
Published in PLoS pathogens (01.01.2020)
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Safety, acceptability, and pharmacokinetics of a monoclonal antibody-based vaginal multipurpose prevention film (MB66): A Phase I randomized trial
Politch, Joseph A, Cu-Uvin, Susan, Moench, Thomas R, Tashima, Karen T, Marathe, Jai G, Guthrie, Kate M, Cabral, Howard, Nyhuis, Tara, Brennan, Miles, Zeitlin, Larry, Spiegel, Hans M L, Mayer, Kenneth H, Whaley, Kevin J, Anderson, Deborah J
Published in PLoS medicine (01.02.2021)
Published in PLoS medicine (01.02.2021)
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LALAPG variant of the Human Contraception Antibody (HCA) reduces Fc-mediated effector functions while maintaining sperm agglutination activity
Mausser, Emilie, Nador, Ellena, Politch, Joseph A, Pauly, Michael R, Marathe, Jai G, Moench, Thomas R, Zeitlin, Larry, Whaley, Kevin J, Anderson, Deborah J
Published in PloS one (30.03.2023)
Published in PloS one (30.03.2023)
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SPL7013 Gel (VivaGel®) retains potent HIV-1 and HSV-2 inhibitory activity following vaginal administration in humans
Price, Clare F, Tyssen, David, Sonza, Secondo, Davie, Ashley, Evans, Sonya, Lewis, Gareth R, Xia, Shirley, Spelman, Tim, Hodsman, Peter, Moench, Thomas R, Humberstone, Andrew, Paull, Jeremy R A, Tachedjian, Gilda
Published in PloS one (15.09.2011)
Published in PloS one (15.09.2011)
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Journal Article
Anti-HIV-1 Activity of Lactic Acid in Human Cervicovaginal Fluid
Tyssen, David, Wang, Ying-Ying, Hayward, Joshua A, Agius, Paul A, DeLong, Kevin, Aldunate, Muriel, Ravel, Jacques, Moench, Thomas R, Cone, Richard A, Tachedjian, Gilda
Published in mSphere (05.07.2018)
Published in mSphere (05.07.2018)
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Inhaled “Muco‐Trapping” Monoclonal Antibody Effectively Treats Established Respiratory Syncytial Virus (RSV) Infections
McSweeney, Morgan D., Alnajjar, Sarhad, Schaefer, Alison M., Richardson, Zach, Wolf, Whitney, Stewart, Ian, Sriboonyapirat, Pun, McCallen, Justin, Farmer, Ellen, Nzati, Bernadette, Lord, Sam, Farrer, Brian, Moench, Thomas R., Kumar, Priya A., Arora, Harendra, Pickles, Raymond J., Hickey, Anthony J., Ackermann, Mark, Lai, Samuel K.
Published in Advanced science (01.03.2024)
Published in Advanced science (01.03.2024)
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Production and characterization of a human antisperm monoclonal antibody against CD52g for topical contraception in women
Baldeon-Vaca, Gabriela, Marathe, Jai G., Politch, Joseph A., Mausser, Emilie, Pudney, Jeffrey, Doud, James, Nador, Ellena, Zeitlin, Larry, Pauly, Michael, Moench, Thomas R., Brennan, Miles, Whaley, Kevin J., Anderson, Deborah J.
Published in EBioMedicine (01.07.2021)
Published in EBioMedicine (01.07.2021)
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ZB-06, a vaginal film containing an engineered human contraceptive antibody (HC4-N), demonstrates safety and efficacy in a phase 1 postcoital test and safety study
Thurman, Andrea R., Moench, Thomas R., Hoke, Marshall, Politch, Joseph A., Cabral, Howard, Mausser, Emilie, Nador, Ellena, Morton, Josh, Hamorsky, Krystal, Swope, Kelsi, Bratcher, Barry, Anderson, Deborah J., Whaley, Kevin J.
Published in American journal of obstetrics and gynecology (01.06.2023)
Published in American journal of obstetrics and gynecology (01.06.2023)
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Journal Article
Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women
ABDOOL KARIM, Salim S, RICHARDSON, Barbra A, MOENCH, Thomas R, PIWOWAR-MANNING, Estelle, MASSE, Benoît, HILLIER, Sharon L, SOTO-TORRES, Lydia, RAMJEE, Gita, HOFFMAN, Irving F, CHIRENJE, Zvavahera M, TAHA, Taha, KAPINA, Muzala, MASLANKOWSKI, Lisa, COLETTI, Anne, PROFY, Albert
Published in AIDS (London) (24.04.2011)
Published in AIDS (London) (24.04.2011)
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Engineering monoclonal antibody-based contraception and multipurpose prevention technologies
Anderson, Deborah J, Politch, Joseph A, Cone, Richard A, Zeitlin, Larry, Lai, Samuel K, Santangelo, Philip J, Moench, Thomas R, Whaley, Kevin J
Published in Biology of reproduction (01.08.2020)
Published in Biology of reproduction (01.08.2020)
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Hexavalent sperm-binding IgG antibody released from vaginal film for development of potent on-demand nonhormonal female contraception
Shrestha, Bhawana, Vincent, Kathleen, Schaefer, Alison, Zhu, Yong, Vargas, Gracie, Motamedi, Massoud, Swope, Kelsi, Morton, Josh, Simpson, Carrie, Pham, Henry, Brennan, Miles B, Pauly, Michael H, Zeitlin, Larry, Bratcher, Barry, Whaley, Kevin J, Moench, Thomas R, Lai, Samuel K
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2021)
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Engineering tetravalent IgGs with enhanced agglutination potencies for trapping vigorously motile sperm in mucin matrix
Shrestha, Bhawana, Schaefer, Alison, Chavez, Elizabeth C., Kopp, Alexander J., Jacobs, Timothy M., Moench, Thomas R., Lai, Samuel K.
Published in Acta biomaterialia (01.11.2020)
Published in Acta biomaterialia (01.11.2020)
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An acceptability and safety study of the Duet® cervical barrier and gel delivery system in Zimbabwe
Montgomery, Elizabeth T, Woodsong, Cynthia, Musara, Petina, Cheng, Helen, Chipato, Tsungai, Moench, Thomas R, Spielberg, Freya, Straten, Ariane
Published in Journal of the International AIDS Society (05.08.2010)
Published in Journal of the International AIDS Society (05.08.2010)
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Engineering sperm-binding IgG antibodies for the development of an effective nonhormonal female contraception
Shrestha, Bhawana, Schaefer, Alison, Zhu, Yong, Saada, Jamal, Jacobs, Timothy M, Chavez, Elizabeth C, Olmsted, Stuart S, Cruz-Teran, Carlos A, Vaca, Gabriela Baldeon, Vincent, Kathleen, Moench, Thomas R, Lai, Samuel K
Published in Science translational medicine (11.08.2021)
Published in Science translational medicine (11.08.2021)
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