Functionally Selective Dopamine D2, D3 Receptor Partial Agonists
Möller, Dorothee, Kling, Ralf C, Skultety, Marika, Leuner, Kristina, Hübner, Harald, Gmeiner, Peter
Published in Journal of medicinal chemistry (12.06.2014)
Published in Journal of medicinal chemistry (12.06.2014)
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Structure-guided development of heterodimer-selective GPCR ligands
Hübner, Harald, Schellhorn, Tamara, Gienger, Marie, Schaab, Carolin, Kaindl, Jonas, Leeb, Laurin, Clark, Timothy, Möller, Dorothee, Gmeiner, Peter
Published in Nature communications (26.07.2016)
Published in Nature communications (26.07.2016)
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Journal Article
The Supramolecular Organization of the C. elegans Nuclear Lamin Filament
Ben-Harush, Kfir, Wiesel, Naama, Frenkiel-Krispin, Daphna, Moeller, Dorothee, Soreq, Eyal, Aebi, Ueli, Herrmann, Harald, Gruenbaum, Yosef, Medalia, Ohad
Published in Journal of molecular biology (13.03.2009)
Published in Journal of molecular biology (13.03.2009)
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Journal Article
Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5‑a]pyridine Substructure
Möller, Dorothee, Banerjee, Ashutosh, Uzuneser, Taygun C, Skultety, Marika, Huth, Tobias, Plouffe, Bianca, Hübner, Harald, Alzheimer, Christian, Friedland, Kristina, Müller, Christian P, Bouvier, Michel, Gmeiner, Peter
Published in Journal of medicinal chemistry (13.04.2017)
Published in Journal of medicinal chemistry (13.04.2017)
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Journal Article
1,4-Disubstituted aromatic piperazines with high 5-HT2A/D-2 selectivity: Quantitative structure-selectivity investigations, docking, synthesis and biological evaluation
Moeller, Dorothee, Salama, Ismail, Kling, Ralf C., Huebner, Harald, Gmeiner, Peter
Published in Bioorganic & medicinal chemistry (15.09.2015)
Published in Bioorganic & medicinal chemistry (15.09.2015)
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Journal Article
progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization
Taimen, Pekka, Pfleghaar, Katrin, Shimi, Takeshi, Möller, Dorothee, Ben-Harush, Kfir, Erdos, Michael R, Adam, Stephen A, Herrmann, Harald, Medalia, Ohad, Collins, Francis S, Goldman, Anne E, Goldman, Robert D
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (08.12.2009)
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Journal Article
Structure-Based Design and Discovery of New M2 Receptor Agonists
Fish, Inbar, Stößel, Anne, Eitel, Katrin, Valant, Celine, Albold, Sabine, Huebner, Harald, Möller, Dorothee, Clark, Mary J, Sunahara, Roger K, Christopoulos, Arthur, Shoichet, Brian K, Gmeiner, Peter
Published in Journal of medicinal chemistry (22.11.2017)
Published in Journal of medicinal chemistry (22.11.2017)
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First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome
Kapeller, Johannes, Houghton, Lesley A., Mönnikes, Hubert, Walstab, Jutta, Möller, Dorothee, Bönisch, Heinz, Burwinkel, Barbara, Autschbach, Frank, Funke, Benjamin, Lasitschka, Felix, Gassler, Nikolaus, Fischer, Christine, Whorwell, Peter J., Atkinson, Wendy, Fell, Catherine, Büchner, Karl J., Schmidtmann, Marco, van der Voort, Ivo, Wisser, Anna-Sophia, Berg, Thomas, Rappold, Gudrun, Niesler, Beate
Published in Human molecular genetics (01.10.2008)
Published in Human molecular genetics (01.10.2008)
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Journal Article
Characterization of the Novel Human Serotonin Receptor Subunits 5-HT3C,5-HT3D, and 5-HT3E
Beate Niesler, Jutta Walstab, Sandra Combrink, Dorothee Möller, Johannes Kapeller, Jens Rietdorf, Heinz Bönisch, Manfred Göthert, Gudrun Rappold, Michael Brüss
Published in Molecular pharmacology (01.07.2007)
Published in Molecular pharmacology (01.07.2007)
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Serotonin receptor diversity in the human colon: Expression of serotonin type 3 receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E
Kapeller, Johannes, Möller, Dorothee, Lasitschka, Felix, Autschbach, Frank, Hovius, Ruud, Rappold, Gudrun, Brüss, Michael, Gershon, Michael D., Niesler, Beate
Published in Journal of comparative neurology (1911) (15.02.2011)
Published in Journal of comparative neurology (1911) (15.02.2011)
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RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT3A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits
Walstab, Jutta, Hammer, Christian, Lasitschka, Felix, Möller, Dorothee, Connolly, Christopher N., Rappold, Gudrun, Brüss, Michael, Bönisch, Heinz, Niesler, Beate
Published in The Journal of biological chemistry (27.08.2010)
Published in The Journal of biological chemistry (27.08.2010)
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5-HTTLPR and STin2 polymorphisms in the serotonin transporter gene and irritable bowel syndrome: effect of bowel habit and sex
Niesler, Beate, Kapeller, Johannes, Fell, Catherine, Atkinson, Wendy, Möller, Dorothee, Fischer, Christine, Whorwell, Peter, Houghton, Lesley A
Published in European journal of gastroenterology & hepatology (01.07.2010)
Published in European journal of gastroenterology & hepatology (01.07.2010)
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Journal Article
Characterization of the Novel Human Serotonin Receptor Subunits 5-HT sub(3C),5-HT sub(3D), and 5-HT sub(3E)
Niesler, Beate, Walstab, Jutta, Combrink, Sandra, Moeller, Dorothee, Kapeller, Johannes, Rietdorf, Jens, Boenisch, Heinz, Goethert, Manfred, Rappold, Gudrun, Bruess, Michael
Published in Molecular pharmacology (01.07.2007)
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Published in Molecular pharmacology (01.07.2007)
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