Discovery of High-Affinity Ligands of σ1 Receptor, ERG2, and Emopamil Binding Protein by Pharmacophore Modeling and Virtual Screening
Laggner, Christian, Schieferer, Claudia, Fiechtner, Birgit, Poles, Gloria, Hoffmann, Rémy D, Glossmann, Hartmut, Langer, Thierry, Moebius, Fabian F
Published in Journal of medicinal chemistry (28.07.2005)
Published in Journal of medicinal chemistry (28.07.2005)
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Journal Article
Purification, Molecular Cloning, and Expression of the Mammalian sigma1-Binding Site
Hanner, Markus, Moebius, Fabian F., Flandorfer, Astrid, Knaus, Hans-Günther, Striessnig, Jörg, Kempner, Ellis, Glossmann, Hartmut
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.1996)
Published in Proceedings of the National Academy of Sciences - PNAS (23.07.1996)
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Journal Article
High affinity of sigma1‐binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8–C7 isomerase
Moebius, Fabian F, Reiter, Raphael J, Hanner, Markus, Glossmann, Hartmut
Published in British journal of pharmacology (01.05.1997)
Published in British journal of pharmacology (01.05.1997)
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Journal Article
Mutations in the Δ7-sterol reductase gene in patients with the Smith–Lemli–Opitz syndrome
Fitzky, Barbara U., Witsch-Baumgartner, Martina, Erdel, Martin, Lee, Joon No, Paik, Young-Ki, Glossmann, Hartmut, Utermann, Gerd, Moebius, Fabian F.
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.1998)
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Journal Article
Isolation of differentially expressed genes in NPM‐ALK‐positive anaplastic large cell lymphoma
Villalva, Claire, Trempat, Pascal, Greenland, Catherine, Thomas, Charles, Girard, Jean Philippe, Moebius, Fabian, Delsol, Georges, Brousset, Pierre
Published in British journal of haematology (01.09.2002)
Published in British journal of haematology (01.09.2002)
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Journal Article
Expression of the purported sigma1 (σ1) receptor in the mammalian brain and its possible relevance in deficits induced by antagonism of the NMDA receptor complex as revealed using an antisense strategy
Kitaichi, Kiyoyuki, Chabot, Jean-Guy, Moebius, Fabian F., Flandorfer, Astrid, Glossmann, Hartmut, Quirion, Rémi
Published in Journal of chemical neuroanatomy (01.12.2000)
Published in Journal of chemical neuroanatomy (01.12.2000)
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Journal Article
7-Dehydrocholesterol–dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
Fitzky, Barbara U., Moebius, Fabian F., Asaoka, Hitoshi, Waage-Baudet, Heather, Xu, Liwen, Xu, Guorong, Maeda, Nobuyo, Kluckman, Kimberly, Hiller, Sylvia, Yu, Hongwei, Batta, Ashok K., Shefer, Sarah, Chen, Thomas, Salen, Gerald, Sulik, Kathleen, Simoni, Robert D., Ness, Gene C., Glossmann, Hartmut, Patel, Shailendra B., Tint, G.S.
Published in The Journal of clinical investigation (15.09.2001)
Published in The Journal of clinical investigation (15.09.2001)
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Journal Article
Histidine77, Glutamic Acid81, Glutamic Acid123, Threonine126, Asparagine194, and Tryptophan197 of the Human Emopamil Binding Protein Are Required for in Vivo Sterol Δ8−Δ7 Isomerization
Moebius, Fabian F, Soellner, Kristina E. M, Fiechtner, Birgit, Huck, Christian W, Bonn, Günther, Glossmann, Hartmut
Published in Biochemistry (Easton) (19.01.1999)
Published in Biochemistry (Easton) (19.01.1999)
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Journal Article
High affinity of sigma 1 ‐binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C 8 –C 7 isomerase
Moebius, Fabian F, Reiter, Raphael J, Hanner, Markus, Glossmann, Hartmut
Published in British journal of pharmacology (03.02.2009)
Published in British journal of pharmacology (03.02.2009)
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Journal Article
Mutations in the Δ 7-sterol Reductase Gene in Patients with the Smith--Lemli--Opitz Syndrome
Fitzky, Barbara U., Witsch-Baumgartner, Martina, Erdel, Martin, Lee, Joon No, Paik, Young-Ki, Glossmann, Hartmut, Utermann, Gerd, Moebius, Fabian F.
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (07.07.1998)
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Journal Article
7-Dehydrocholesterol-dependent proteolysis of HMG-CoA reductase suppresses sterol biosynthesis in a mouse model of Smith-Lemli-Opitz/RSH syndrome
Fitzky, B U, Moebius, F F, Asaoka, H, Waage-Baudet, H, Xu, L, Xu, G, Maeda, N, Kluckman, K, Hiller, S, Yu, H, Batta, A K, Shefer, S, Chen, T, Salen, G, Sulik, K, Simoni, R D, Ness, G C, Glossmann, H, Patel, S B, Tint, G S
Published in The Journal of clinical investigation (01.09.2001)
Published in The Journal of clinical investigation (01.09.2001)
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Journal Article
Discovery of high-affinity ligands of sigma1 receptor, ERG2, and emopamil binding protein by pharmacophore modeling and virtual screening
Laggner, Christian, Schieferer, Claudia, Fiechtner, Birgit, Poles, Gloria, Hoffmann, Rémy D, Glossmann, Hartmut, Langer, Thierry, Moebius, Fabian F
Published in Journal of medicinal chemistry (28.07.2005)
Get full text
Published in Journal of medicinal chemistry (28.07.2005)
Journal Article
Discovery of High-Affinity Ligands of σ 1 Receptor, ERG2, and Emopamil Binding Protein by Pharmacophore Modeling and Virtual Screening
Laggner, Christian, Schieferer, Claudia, Fiechtner, Birgit, Poles, Gloria, Hoffmann, Rémy D., Glossmann, Hartmut, Langer, Thierry, Moebius, Fabian F.
Published in Journal of medicinal chemistry (01.07.2005)
Published in Journal of medicinal chemistry (01.07.2005)
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Journal Article
Genetic Defects in Postsqualene Cholesterol Biosynthesis
Moebius, Fabian F., Fitzky, Barbara U., Glossmann, Hartmut
Published in Trends in Endocrinology & Metabolism (01.04.2000)
Published in Trends in Endocrinology & Metabolism (01.04.2000)
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Book Review
Journal Article