In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states
Neagu, Alex, van Genderen, Emiel, Escudero, Irene, Verwegen, Lucas, Kurek, Dorota, Lehmann, Johannes, Stel, Jente, Dirks, René A. M., van Mierlo, Guido, Maas, Alex, Eleveld, Cindy, Ge, Yang, den Dekker, Alexander. T., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Modic, Miha, Drukker, Micha, Jansen, Joop H., Rivron, Nicolas C., Baart, Esther B., Marks, Hendrik, ten Berge, Derk
Published in Nature cell biology (01.05.2020)
Published in Nature cell biology (01.05.2020)
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Journal Article
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis
Tyzack, Giulia E, Luisier, Raphaelle, Taha, Doaa M, Neeves, Jacob, Modic, Miha, Mitchell, Jamie S, Meyer, Ione, Greensmith, Linda, Newcombe, Jia, Ule, Jernej, Luscombe, Nicholas M, Patani, Rickie
Published in Brain (London, England : 1878) (01.09.2019)
Published in Brain (London, England : 1878) (01.09.2019)
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Journal Article
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanishi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Published in Nature communications (24.11.2020)
Published in Nature communications (24.11.2020)
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Journal Article
Cross-Regulation between TDP-43 and Paraspeckles Promotes Pluripotency-Differentiation Transition
Modic, Miha, Grosch, Markus, Rot, Gregor, Schirge, Silvia, Lepko, Tjasa, Yamazaki, Tomohiro, Lee, Flora C.Y., Rusha, Ejona, Shaposhnikov, Dmitry, Palo, Michael, Merl-Pham, Juliane, Cacchiarelli, Davide, Rogelj, Boris, Hauck, Stefanie M., von Mering, Christian, Meissner, Alexander, Lickert, Heiko, Hirose, Tetsuro, Ule, Jernej, Drukker, Micha
Published in Molecular cell (06.06.2019)
Published in Molecular cell (06.06.2019)
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Journal Article
High-Resolution RNA Maps Suggest Common Principles of Splicing and Polyadenylation Regulation by TDP-43
Rot, Gregor, Wang, Zhen, Huppertz, Ina, Modic, Miha, Lenče, Tina, Hallegger, Martina, Haberman, Nejc, Curk, Tomaž, von Mering, Christian, Ule, Jernej
Published in Cell reports (Cambridge) (02.05.2017)
Published in Cell reports (Cambridge) (02.05.2017)
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Journal Article
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency
Mulholland, Christopher B., Traube, Franziska R., Ugur, Enes, Parsa, Edris, Eckl, Eva-Maria, Schönung, Maximilian, Modic, Miha, Bartoschek, Michael D., Stolz, Paul, Ryan, Joel, Carell, Thomas, Leonhardt, Heinrich, Bultmann, Sebastian
Published in Scientific reports (21.07.2020)
Published in Scientific reports (21.07.2020)
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Journal Article
Author Correction: Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
Mulholland, Christopher B., Nishiyama, Atsuya, Ryan, Joel, Nakamura, Ryohei, Yiğit, Merve, Glück, Ivo M., Trummer, Carina, Qin, Weihua, Bartoschek, Michael D., Traube, Franziska R., Parsa, Edris, Ugur, Enes, Modic, Miha, Acharya, Aishwarya, Stolz, Paul, Ziegenhain, Christoph, Wierer, Michael, Enard, Wolfgang, Carell, Thomas, Lamb, Don C., Takeda, Hiroyuki, Nakanishi, Makoto, Bultmann, Sebastian, Leonhardt, Heinrich
Published in Nature communications (17.12.2020)
Published in Nature communications (17.12.2020)
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Journal Article
CLIPing the brain: Studies of protein–RNA interactions important for neurodegenerative disorders
Modic, Miha, Ule, Jernej, Sibley, Christopher R.
Published in Molecular and cellular neuroscience (01.09.2013)
Published in Molecular and cellular neuroscience (01.09.2013)
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Journal Article
Pathological ASXL1 Mutations and Protein Variants Impair Neural Crest Development
Matheus, Friederike, Rusha, Ejona, Rehimi, Rizwan, Molitor, Lena, Pertek, Anna, Modic, Miha, Feederle, Regina, Flatley, Andrew, Kremmer, Elisabeth, Geerlof, Arie, Rishko, Valentyna, Rada-Iglesias, Alvaro, Drukker, Micha
Published in Stem cell reports (14.05.2019)
Published in Stem cell reports (14.05.2019)
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Journal Article
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
Rogelj, Boris, Easton, Laura E., Bogu, Gireesh K., Stanton, Lawrence W., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Sugimoto, Yoichiro, Modic, Miha, Haberman, Nejc, Tollervey, James, Fujii, Ritsuko, Takumi, Toru, Shaw, Christopher E., Ule, Jernej
Published in Scientific reports (28.08.2012)
Published in Scientific reports (28.08.2012)
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Journal Article
Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin , vcam 1 and integrin α4/β1
Hipke, Katrin, Pitter, Bettina, Hruscha, Alexander, van Bebber, Frauke, Modic, Miha, Bansal, Vikas, Lewandowski, Sebastian A, Orozco, Denise, Edbauer, Dieter, Bonn, Stefan, Haass, Christian, Pohl, Ulrich, Montanez, Eloi, Schmid, Bettina
Published in Frontiers in cell and developmental biology (2023)
Published in Frontiers in cell and developmental biology (2023)
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Journal Article
Recursive splicing in long vertebrate genes
Sibley, Christopher R., Emmett, Warren, Blazquez, Lorea, Faro, Ana, Haberman, Nejc, Briese, Michael, Trabzuni, Daniah, Ryten, Mina, Weale, Michael E., Hardy, John, Modic, Miha, Curk, Tomaž, Wilson, Stephen W., Plagnol, Vincent, Ule, Jernej
Published in Nature (London) (21.05.2015)
Published in Nature (London) (21.05.2015)
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Journal Article
Choroid plexus‐derived miR‐204 regulates the number of quiescent neural stem cells in the adult brain
Lepko, Tjasa, Pusch, Melanie, Müller, Tamara, Schulte, Dorothea, Ehses, Janina, Kiebler, Michael, Hasler, Julia, Huttner, Hagen B, Vandenbroucke, Roosmarijn E, Vandendriessche, Charysse, Modic, Miha, Martin‐Villalba, Ana, Zhao, Sheng, LLorens‐Bobadilla, Enric, Schneider, Anja, Fischer, Andre, Breunig, Christopher T, Stricker, Stefan H, Götz, Magdalena, Ninkovic, Jovica
Published in The EMBO journal (02.09.2019)
Published in The EMBO journal (02.09.2019)
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Journal Article
Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain
Rogelj, Boris, Easton, Laura E., Bogu, Gireesh K., Stanton, Lawrence W., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Sugimoto, Yoichiro, Modic, Miha, Haberman, Nejc, Tollervey, James, Fujii, Ritsuko, Takumi, Toru, Shaw, Christopher E., Ule, Jernej
Published in Scientific reports (28.08.2012)
Published in Scientific reports (28.08.2012)
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Journal Article
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency
Qin, Weihua, Ugur, Enes, Mulholland, Christopher B, Bultmann, Sebastian, Solovei, Irina, Modic, Miha, Smets, Martha, Wierer, Michael, Forné, Ignasi, Imhof, Axel, Cardoso, M Cristina, Leonhardt, Heinrich
Published in Nucleic acids research (21.07.2021)
Published in Nucleic acids research (21.07.2021)
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Journal Article
Poised PABP–RNA hubs implement signal-dependent mRNA decay in development
Modic, Miha, Kuret, Klara, Steinhauser, Sebastian, Faraway, Rupert, van Genderen, Emiel, Ruiz de Los Mozos, Igor, Novljan, Jona, Vičič, Žiga, Lee, Flora C. Y., ten Berge, Derk, Luscombe, Nicholas M., Ule, Jernej
Published in Nature structural & molecular biology (01.09.2024)
Published in Nature structural & molecular biology (01.09.2024)
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Journal Article
Nuclear RNA foci from C9ORF72 expansion mutation form paraspeckle-like bodies
Bajc Česnik, Ana, Darovic, Simona, Prpar Mihevc, Sonja, Štalekar, Maja, Malnar, Mirjana, Motaln, Helena, Lee, Youn-Bok, Mazej, Julija, Pohleven, Jure, Grosch, Markus, Modic, Miha, Fonovič, Marko, Turk, Boris, Drukker, Micha, Shaw, Christopher E, Rogelj, Boris
Published in Journal of cell science (07.03.2019)
Published in Journal of cell science (07.03.2019)
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