삼환계 GPR65 조절제
NAYLOR ALAN, MCCARTHY TOM, MOCHEL TOBIAS, ESVAN YANNICK, IEVA MARIA, MILLER DAVID, MILNE GAVIN, FEUTRILL JOHN
Year of Publication 24.06.2024
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Year of Publication 24.06.2024
Patent
Scaffold-hopping with zwitterionic CCR3 antagonists: Identification and optimisation of a series with good potency and pharmacokinetics leading to the discovery of AZ12436092
Bahl, Ash, Barton, Patrick, Bowers, Keith, Caffrey, Moya V., Denton, Rebecca, Gilmour, Peter, Hawley, Shaun, Linannen, Tero, Luckhurst, Christopher A., Mochel, Tobias, Perry, Matthew W.D., Riley, Robert J., Roe, Emma, Springthorpe, Brian, Stein, Linda, Webborn, Peter
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Journal Article
The discovery of CCR3/H-1 dual antagonists with reduced hERG risk
Bahl, Ash, Barton, Patrick, Bowers, Keith, Brough, Steven, Evans, Richard, Luckhurst, Christopher A., Mochel, Tobias, Perry, Matthew W. D., Rigby, Aaron, Riley, Robert J., Sanganee, Hitesh, Sisson, Adam, Springthorpe, Brian
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Journal Article
The discovery of CCR3/H1 dual antagonists with reduced hERG risk
Bahl, Ash, Barton, Patrick, Bowers, Keith, Brough, Steven, Evans, Richard, Luckhurst, Christopher A., Mochel, Tobias, Perry, Matthew W.D., Rigby, Aaron, Riley, Robert J., Sanganee, Hitesh, Sisson, Adam, Springthorpe, Brian
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
Published in Bioorganic & medicinal chemistry letters (01.11.2012)
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Journal Article
PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS
TIDEN ANNA KARIN, MOCHEL TOBIAS, MCINALLY THOMAS, BENNETT NICHOLAS J, THOM STEPHEN
Year of Publication 31.08.2010
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Year of Publication 31.08.2010
Patent
TRICYCLIC GPR65 MODULATORS
NAYLOR, Alan, MCCARTHY, Tom, MOCHEL, Tobias, MILLER, David, ESVAN, Yannick, MILNE, Gavin, FEUTRILL, John, IEVA, Maria
Year of Publication 28.08.2024
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Year of Publication 28.08.2024
Patent
TRICYCLIC GPR65 MODULATORS
NAYLOR, Alan, MCCARTHY, Tom, MOCHEL, Tobias, MILLER, David, ESVAN, Yannick, MILNE, Gavin, FEUTRILL, John, IEVA, Maria
Year of Publication 30.05.2024
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Year of Publication 30.05.2024
Patent
TRICYCLIC GPR65 MODULATORS
NAYLOR, Alan, MCCARTHY, Tom, MOCHEL, Tobias, MILLER, David, ESVAN, Yannick, MILNE, Gavin, FEUTRILL, John, IEVA, Maria
Year of Publication 27.04.2023
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Year of Publication 27.04.2023
Patent
TRICYCLIC GPR65 MODULATORS
ESVAN, YANNICK, MOCHEL, TOBIAS, IEVA, MARIA, MILLER, DAVID, MILNE, GAVIN, MCCARTHY, TOM, NAYLOR, ALAN, FEUTRILL, JOHN
Year of Publication 27.04.2023
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Year of Publication 27.04.2023
Patent
TRICYCLIC GPR65 MODULATORS
MCCARTHY Tom, MOCHEL Tobias, IEVA Maria, MILLER David, NAYLOR Alan, ESVAN Yannick, MILNE Gavin, FEUTRILL John
Year of Publication 02.05.2024
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Year of Publication 02.05.2024
Patent
PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS
MOCHEL, TOBIAS, MCINALLY, THOMAS, BENNETT, NICHOLAS J, THOM, STEPHEN, TIDEN, ANNA-KARIN
Year of Publication 24.05.2016
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Year of Publication 24.05.2016
Patent
Derivados de pirimidina para o tratamento da asma, copd, rinite alérgica, conjuntivite alérgica, dermatite atópica, câncer, hepatite b, hepatite c, hiv, hpv, infecções bacterianas e dermatose
NICHOLAS J. BENNETT, TOBIAS MOCHEL, STEPHEN THOM, ANNA-KARIN TIDÉN, THOMAS MCINALLY
Year of Publication 05.05.2015
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Year of Publication 05.05.2015
Patent
piperidinylmethylpiperidine derivatives and their use as chemokine modulators
LUCKHURST, CHRISTOPHER, MOCHEL, TOBIAS, SPRINGTHORPE, BRIAN, CAFFREY, MOYA, PERRY, MATTHEW
Year of Publication 05.12.2012
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Year of Publication 05.12.2012
Patent
8-OXOADENINE DERIVATIVES AS IMMUNO-MODULATORS
MOCHEL, TOBIAS, MCINALLY, THOMAS, THOM, STEPHEN, BONNERT, ROGER VICTOR
Year of Publication 08.08.2012
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Year of Publication 08.08.2012
Patent
PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF ASTHMA, COPD, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS, ATOPIC DERMATITIS, CANCER, HEPATITIS B, HEPATITIS C, HIV, HPV, BACTERIAL INFECTIONS AND DERMATOSIS
MOCHEL, Tobias, TIDÉN, Anna-Karin, MCINALLY, Thomas, BENNETT, Nicholas, J, THOM, Stephen
Year of Publication 20.04.2014
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Year of Publication 20.04.2014
Patent
Compounds
Bonnert, Roger Victor, McInally, Thomas, Mochel, Tobias, Thom, Stephen
Year of Publication 29.11.2011
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Year of Publication 29.11.2011
Patent