Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex
Mkrtchyan, Garik V., Üçal, Muammer, Müllebner, Andrea, Dumitrescu, Sergiu, Kames, Martina, Moldzio, Rudolf, Molcanyi, Marek, Schaefer, Samuel, Weidinger, Adelheid, Schaefer, Ute, Hescheler, Juergen, Duvigneau, Johanna Catharina, Redl, Heinz, Bunik, Victoria I., Kozlov, Andrey V.
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2018)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2018)
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Journal Article
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
Mkrtchyan, Garik V, Veviorskiy, Alexander, Izumchenko, Evgeny, Shneyderman, Anastasia, Pun, Frank W, Ozerov, Ivan V, Aliper, Alex, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Published in Cell death & disease (26.11.2022)
Published in Cell death & disease (26.11.2022)
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Journal Article
Oxoglutarate dehydrogenase complex controls glutamate-mediated neuronal death
Weidinger, Adelheid, Milivojev, Nadja, Hosmann, Arthur, Duvigneau, J. Catharina, Szabo, Csaba, Törö, Gabor, Rauter, Laurin, Vaglio-Garro, Annette, Mkrtchyan, Garik V., Trofimova, Lidia, Sharipov, Rinat R., Surin, Alexander M., Krasilnikova, Irina A., Pinelis, Vsevolod G., Tretter, Laszlo, Moldzio, Rudolf, Bayır, Hülya, Kagan, Valerian E., Bunik, Victoria I., Kozlov, Andrey V.
Published in Redox biology (01.06.2023)
Published in Redox biology (01.06.2023)
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Journal Article
Nuclear morphology is a deep learning biomarker of cellular senescence
Heckenbach, Indra, Mkrtchyan, Garik V, Ezra, Michael Ben, Bakula, Daniela, Madsen, Jakob Sture, Nielsen, Malte Hasle, Oró, Denise, Osborne, Brenna, Covarrubias, Anthony J, Idda, M Laura, Gorospe, Myriam, Mortensen, Laust, Verdin, Eric, Westendorp, Rudi, Scheibye-Knudsen, Morten
Published in Nature aging (01.08.2022)
Published in Nature aging (01.08.2022)
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Journal Article
The Antioxidant Cofactor Alpha-Lipoic Acid May Control Endogenous Formaldehyde Metabolism in Mammals
Shindyapina, Anastasia V, Komarova, Tatiana V, Sheshukova, Ekaterina V, Ershova, Natalia M, Tashlitsky, Vadim N, Kurkin, Alexander V, Yusupov, Ildar R, Mkrtchyan, Garik V, Shagidulin, Murat Y, Dorokhov, Yuri L
Published in Frontiers in neuroscience (01.12.2017)
Published in Frontiers in neuroscience (01.12.2017)
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Journal Article
Positive correlation between rat brain glutamate concentrations and mitochondrial 2-oxoglutarate dehydrogenase activity
Mkrtchyan, Garik V., Graf, Anastasia, Trofimova, Lidia, Ksenofontov, Alexander, Baratova, Ludmila, Bunik, Victoria
Published in Analytical biochemistry (01.07.2018)
Published in Analytical biochemistry (01.07.2018)
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Journal Article
Diurnal regulation of the function of the rat brain glutamate dehydrogenase by acetylation and its dependence on thiamine administration
Aleshin, Vasily A., Mkrtchyan, Garik V., Kaehne, Thilo, Graf, Anastasia V., Maslova, Maria V., Bunik, Victoria I.
Published in Journal of neurochemistry (01.04.2020)
Published in Journal of neurochemistry (01.04.2020)
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Journal Article
Defining the progeria phenome
Worm, Cecilie, Schambye, Maya Elena Ramirez, Mkrtchyan, Garik V, Veviorskiy, Alexander, Shneyderman, Anastasia, Ozerov, Ivan V, Zhavoronkov, Alex, Bakula, Daniela, Scheibye-Knudsen, Morten
Published in Aging (Albany, NY.) (09.02.2024)
Published in Aging (Albany, NY.) (09.02.2024)
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Journal Article
Pharmacological interventions in human aging
Petr, Michael Angelo, Matiyevskaya, Frida, Osborne, Brenna, Berglind, Magnus, Reves, Simon, Zhang, Bin, Ezra, Michael Ben, Carmona-Marin, Lina Maria, Syadzha, Muhammad Farraz, Mediavilla, Marta Cortés, Keijzers, Guido, Bakula, Daniela, Mkrtchyan, Garik V, Scheibye-Knudsen, Morten
Published in Ageing research reviews (01.03.2024)
Published in Ageing research reviews (01.03.2024)
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Journal Article
New methodologies in ageing research
Osborne, Brenna, Bakula, Daniela, Ben Ezra, Michael, Dresen, Charlotte, Hartmann, Esben, Kristensen, Stella M., Mkrtchyan, Garik V., Nielsen, Malte H., Petr, Michael A., Scheibye-Knudsen, Morten
Published in Ageing research reviews (01.09.2020)
Published in Ageing research reviews (01.09.2020)
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Journal Article
Aging and drug discovery
Bakula, Daniela, Aliper, Alexander M, Mamoshina, Polina, Petr, Michael A, Teklu, Amanuel, Baur, Joseph A, Campisi, Judith, Ewald, Collin Y, Georgievskaya, Anastasia, Gladyshev, Vadim N, Kovalchuk, Olga, Lamming, Dudley W, Luijsterburg, Martijn S, Martín-Montalvo, Alejandro, Maudsley, Stuart, Mkrtchyan, Garik V, Moskalev, Alexey, Olshansky, S Jay, Ozerov, Ivan V, Pickett, Alexander, Ristow, Michael, Zhavoronkov, Alex, Scheibye-Knudsen, Morten
Published in Aging (Albany, NY.) (13.11.2018)
Published in Aging (Albany, NY.) (13.11.2018)
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Journal Article
Mineralization of the connective tissue: a complex molecular process leading to age-related loss of function
Shindyapina, Anastasia V, Mkrtchyan, Garik V, Gneteeva, Tatiana, Buiucli, Sveatoslav, Tancowny, B, Kulka, M, Aliper, Alexander, Zhavoronkov, Alexander
Published in Rejuvenation research (01.04.2014)
Published in Rejuvenation research (01.04.2014)
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Journal Article
Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex
Kozlov, Andrey V., Mkrtchyan, Garik V., Üçal, Muammer, Müllebner, Andrea, Dumitrescu, Sergiu, Kames, Martina, Moldzio, Rudolf, Molcanyi, Marek, Schaefer, Samuel, Weidinger, Adelheid, Schaefer, Ute, Hescheler, Juergen, Duvigneau, Johanna Catharina, Redl, Heinz, Bunik, Victoria I.
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2018)
Published in Biochimica et biophysica acta. Bioenergetics (01.09.2018)
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Journal Article
Deep Learning Shows Cellular Senescence Is a Barrier to Cancer Development
Heckenbach, Indra, Michael Ben Ezra, Mkrtchyan, Garik V, Madsen, Jakob Sture, Malte Hasle Nielsen, Oró, Denise, Mortensen, Laust, Verdin, Eric, Westendorp, Rudi, Scheibye-Knudsen, Morten
Published in bioRxiv (19.03.2021)
Published in bioRxiv (19.03.2021)
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