Tankyrase promotes primary precursor miRNA processing to precursor miRNA
Mizutani, Anna, Seimiya, Hiroyuki
Published in Biochemical and biophysical research communications (19.02.2020)
Published in Biochemical and biophysical research communications (19.02.2020)
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Journal Article
RK‐287107, a potent and specific tankyrase inhibitor, blocks colorectal cancer cell growth in a preclinical model
Mizutani, Anna, Yashiroda, Yoko, Muramatsu, Yukiko, Yoshida, Haruka, Chikada, Tsubasa, Tsumura, Takeshi, Okue, Masayuki, Shirai, Fumiyuki, Fukami, Takehiro, Yoshida, Minoru, Seimiya, Hiroyuki
Published in Cancer science (01.12.2018)
Published in Cancer science (01.12.2018)
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Journal Article
ZEB1‐regulated inflammatory phenotype in breast cancer cells
Katsura, Akihiro, Tamura, Yusuke, Hokari, Satoshi, Harada, Mayumi, Morikawa, Masato, Sakurai, Tsubasa, Takahashi, Kei, Mizutani, Anna, Nishida, Jun, Yokoyama, Yuichiro, Morishita, Yasuyuki, Murakami, Takashi, Ehata, Shogo, Miyazono, Kohei, Koinuma, Daizo
Published in Molecular oncology (01.09.2017)
Published in Molecular oncology (01.09.2017)
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Journal Article
CNOT3 targets negative cell cycle regulators in non-small cell lung cancer development
Shirai, Yo-Taro, Mizutani, Anna, Nishijima, Saori, Horie, Masafumi, Kikuguchi, Chisato, Elisseeva, Olga, Yamamoto, Tadashi
Published in Oncogene (01.04.2019)
Published in Oncogene (01.04.2019)
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Journal Article
APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer
Tanaka, Noritaka, Mashima, Tetsuo, Mizutani, Anna, Sato, Ayana, Aoyama, Aki, Gong, Bo, Yoshida, Haruka, Muramatsu, Yukiko, Nakata, Kento, Matsuura, Masaaki, Katayama, Ryohei, Nagayama, Satoshi, Fujita, Naoya, Sugimoto, Yoshikazu, Seimiya, Hiroyuki
Published in Molecular cancer therapeutics (01.04.2017)
Published in Molecular cancer therapeutics (01.04.2017)
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Journal Article
Design and Discovery of an Orally Efficacious Spiroindolinone-Based Tankyrase Inhibitor for the Treatment of Colon Cancer
Shirai, Fumiyuki, Mizutani, Anna, Yashiroda, Yoko, Tsumura, Takeshi, Kano, Yuko, Muramatsu, Yukiko, Chikada, Tsubasa, Yuki, Hitomi, Niwa, Hideaki, Sato, Shin, Washizuka, Kenichi, Koda, Yasuko, Mazaki, Yui, Jang, Myung-Kyu, Yoshida, Haruka, Nagamori, Akiko, Okue, Masayuki, Watanabe, Takashi, Kitamura, Kouichi, Shitara, Eiki, Honma, Teruki, Umehara, Takashi, Shirouzu, Mikako, Fukami, Takehiro, Seimiya, Hiroyuki, Yoshida, Minoru, Koyama, Hiroo
Published in Journal of medicinal chemistry (23.04.2020)
Published in Journal of medicinal chemistry (23.04.2020)
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Journal Article
Discovery of Novel Spiroindoline Derivatives as Selective Tankyrase Inhibitors
Shirai, Fumiyuki, Tsumura, Takeshi, Yashiroda, Yoko, Yuki, Hitomi, Niwa, Hideaki, Sato, Shin, Chikada, Tsubasa, Koda, Yasuko, Washizuka, Kenichi, Yoshimoto, Nobuko, Abe, Masako, Onuki, Tetsuo, Mazaki, Yui, Hirama, Chizuko, Fukami, Takehiro, Watanabe, Hirofumi, Honma, Teruki, Umehara, Takashi, Shirouzu, Mikako, Okue, Masayuki, Kano, Yuko, Watanabe, Takashi, Kitamura, Kouichi, Shitara, Eiki, Muramatsu, Yukiko, Yoshida, Haruka, Mizutani, Anna, Seimiya, Hiroyuki, Yoshida, Minoru, Koyama, Hiroo
Published in Journal of medicinal chemistry (11.04.2019)
Published in Journal of medicinal chemistry (11.04.2019)
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Journal Article
Dynamics of chromatin accessibility during TGF-β-induced EMT of Ras-transformed mammary gland epithelial cells
Arase, Mayu, Tamura, Yusuke, Kawasaki, Natsumi, Isogaya, Kazunobu, Nakaki, Ryo, Mizutani, Anna, Tsutsumi, Shuichi, Aburatani, Hiroyuki, Miyazono, Kohei, Koinuma, Daizo
Published in Scientific reports (26.04.2017)
Published in Scientific reports (26.04.2017)
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Journal Article
BMP Sustains Embryonic Stem Cell Self-Renewal through Distinct Functions of Different Krüppel-like Factors
Morikawa, Masato, Koinuma, Daizo, Mizutani, Anna, Kawasaki, Natsumi, Holmborn, Katarina, Sundqvist, Anders, Tsutsumi, Shuichi, Watabe, Tetsuro, Aburatani, Hiroyuki, Heldin, Carl-Henrik, Miyazono, Kohei
Published in Stem cell reports (12.01.2016)
Published in Stem cell reports (12.01.2016)
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Journal Article
mTOR signaling mediates resistance to tankyrase inhibitors in Wnt-driven colorectal cancer
Mashima, Tetsuo, Taneda, Yoko, Jang, Myung-Kyu, Mizutani, Anna, Muramatsu, Yukiko, Yoshida, Haruka, Sato, Ayana, Tanaka, Noritaka, Sugimoto, Yoshikazu, Seimiya, Hiroyuki
Published in Oncotarget (18.07.2017)
Published in Oncotarget (18.07.2017)
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Journal Article
Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling
Mizutani, Anna, Saitoh, Masao, Imamura, Takeshi, Miyazawa, Keiji, Miyazono, Kohei
Published in Journal of biochemistry (Tokyo) (01.12.2010)
Published in Journal of biochemistry (Tokyo) (01.12.2010)
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Journal Article
Adaptor protein complex of FRS2β and CIN85/CD2AP provides a novel mechanism for ErbB2/HER2 protein downregulation
Minegishi, Yuriko, Shibagaki, Yoshio, Mizutani, Anna, Fujita, Koji, Tezuka, Tohru, Kinoshita, Masao, Kuroda, Masahiko, Hattori, Seisuke, Gotoh, Noriko
Published in Cancer science (01.03.2013)
Published in Cancer science (01.03.2013)
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Journal Article
APC/PIK3CA mutations and β-catenin status predict tankyrase inhibitor sensitivity of patient-derived colorectal cancer cells
Chen, Mingjue, Mashima, Tetsuo, Oishi, Taichi, Muramatsu, Yukiko, Seto, Yosuke, Takamatsu, Manabu, Kawata, Naomi, Morino, Shun, Nakamura, Ayane, Inaba, Saori, Yuan, Xunmei, Maruyama, Kohei, Suzuki, Mai, Sato, Ayana, Yoshida, Haruka, Jang, Myung-Kyu, Mizutani, Anna, Takeuchi, Kengo, Yamaguchi, Kensei, Shirai, Fumiyuki, Nagayama, Satoshi, Katayama, Ryohei, Seimiya, Hiroyuki
Published in British journal of cancer (31.01.2024)
Published in British journal of cancer (31.01.2024)
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Journal Article
Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program
Vasilaki, Eleftheria, Morikawa, Masato, Koinuma, Daizo, Mizutani, Anna, Hirano, Yudai, Ehata, Shogo, Sundqvist, Anders, Kawasaki, Natsumi, Cedervall, Jessica, Olsson, Anna-Karin, Aburatani, Hiroyuki, Moustakas, Aristidis, Miyazono, Kohei, Heldin, Carl-Henrik
Published in Science signaling (23.08.2016)
Published in Science signaling (23.08.2016)
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Journal Article
Cell Type-specific Target Selection by Combinatorial Binding of Smad2/3 Proteins and Hepatocyte Nuclear Factor 4α in HepG2 Cells
Mizutani, Anna, Koinuma, Daizo, Tsutsumi, Shuichi, Kamimura, Naoko, Morikawa, Masato, Suzuki, Hiroshi I., Imamura, Takeshi, Miyazono, Kohei, Aburatani, Hiroyuki
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article
ZEB 1‐regulated inflammatory phenotype in breast cancer cells
Katsura, Akihiro, Tamura, Yusuke, Hokari, Satoshi, Harada, Mayumi, Morikawa, Masato, Sakurai, Tsubasa, Takahashi, Kei, Mizutani, Anna, Nishida, Jun, Yokoyama, Yuichiro, Morishita, Yasuyuki, Murakami, Takashi, Ehata, Shogo, Miyazono, Kohei, Koinuma, Daizo
Published in Molecular oncology (01.09.2017)
Published in Molecular oncology (01.09.2017)
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Journal Article
Adaptor protein complex of FRS 2β and CIN 85/ CD 2 AP provides a novel mechanism for ErbB2/ HER 2 protein downregulation
Minegishi, Yuriko, Shibagaki, Yoshio, Mizutani, Anna, Fujita, Koji, Tezuka, Tohru, Kinoshita, Masao, Kuroda, Masahiko, Hattori, Seisuke, Gotoh, Noriko
Published in Cancer science (01.03.2013)
Published in Cancer science (01.03.2013)
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Journal Article
Cell type-specific target selection by combinatorial binding of Smad2/3 proteins and hepatocyte nuclear factor 4alpha in HepG2 cells
Mizutani, Anna, Koinuma, Daizo, Tsutsumi, Shuichi, Kamimura, Naoko, Morikawa, Masato, Suzuki, Hiroshi I, Imamura, Takeshi, Miyazono, Kohei, Aburatani, Hiroyuki
Published in The Journal of biological chemistry (26.08.2011)
Published in The Journal of biological chemistry (26.08.2011)
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Journal Article