Discovery of 2-[(E)-2-(7-Fluoro-3-methylquinoxalin-2-yl)vinyl]-6-pyrrolidin-1-yl-N-(tetrahydro-2H-pyran-4-yl)pyrimidin-4-amine Hydrochloride as a Highly Selective PDE10A Inhibitor
Kadoh, Yoichi, Miyoshi, Haruko, Matsumura, Takehiko, Tanaka, Yoshihito, Hongu, Mitsuya, Kimura, Mayumi, Takedomi, Kei, Omori, Kenji, Kotera, Jun, Sasaki, Takashi, Kobayashi, Tamaki, Taniguchi, Hiroyuki, Watanabe, Yumi, Kojima, Koki, Sakamoto, Toshiaki, Himiyama, Toshiyuki, Kawanishi, Eiji
Published in Chemical & pharmaceutical bulletin (2018)
Published in Chemical & pharmaceutical bulletin (2018)
Get full text
Journal Article
Solid-Phase Synthesis of Epigallocatechin Gallate Derivatives
Tanaka, Hiroshi, Miyoshi, Haruko, Chuang, Yu-Cheng, Ando, Yoshio, Takahashi, Takashi
Published in Angewandte Chemie (International ed.) (01.01.2007)
Published in Angewandte Chemie (International ed.) (01.01.2007)
Get full text
Journal Article
Solid-Phase Synthesis of Epigallocatechin Gallate Derivatives
Tanaka, Hiroshi, Miyoshi, Haruko, Chuang, Yu-Cheng, Ando, Yoshio, Takahashi, Takashi
Published in Angewandte Chemie (03.08.2007)
Published in Angewandte Chemie (03.08.2007)
Get full text
Journal Article
Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety
Koizumi, Yuuki, Tanaka, Yoshihito, Matsumura, Takehiko, Kadoh, Yoichi, Miyoshi, Haruko, Hongu, Mitsuya, Takedomi, Kei, Kotera, Jun, Sasaki, Takashi, Taniguchi, Hiroyuki, Watanabe, Yumi, Takakuwa, Misae, Kojima, Koki, Baba, Nobuyuki, Nakamura, Itsuko, Kawanishi, Eiji
Published in Bioorganic & medicinal chemistry (01.08.2019)
Published in Bioorganic & medicinal chemistry (01.08.2019)
Get full text
Journal Article
Solid-phase synthesis of a combinatorial methylated (±)-epigallocatechin gallate library and the growth-inhibitory effects of these compounds on melanoma B16 cells
Tanaka, Hiroshi, Yamanouchi, Maasa, Miyoshi, Haruko, Hirotsu, Keisuke, Tachibana, Hirofumi, Takahashi, Takashi
Published in Chemistry, an Asian journal (04.10.2010)
Published in Chemistry, an Asian journal (04.10.2010)
Get more information
Journal Article
NOVEL COMPOUND AND ITS USE AS PDE10 INHIBITOR
MATSUMURA TAKEHIKO, TANAKA YOSHIHITO, KADO YOICHI, MIYOSHI HARUKO, KAWANISHI EIJI
Year of Publication 11.12.2014
Get full text
Year of Publication 11.12.2014
Patent
Solid‐Phase Synthesis of Epigallocatechin Gallate Derivatives
Tanaka, Hiroshi, Miyoshi, Haruko, Chuang, Yu‐Cheng, Ando, Yoshio, Takahashi, Takashi
Published in Angewandte Chemie (03.08.2007)
Published in Angewandte Chemie (03.08.2007)
Get full text
Journal Article