Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase
Mano, Takashi, Stevens, Rodney W, Ando, Kazuo, Nakao, Kazunari, Okumura, Yoshiyuki, Sakakibara, Minoru, Okumura, Takako, Tamura, Tetsuya, Miyamoto, Kimitaka
Published in Bioorganic & medicinal chemistry (01.09.2003)
Published in Bioorganic & medicinal chemistry (01.09.2003)
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Journal Article
Optimization of Imidazole 5-Lipoxygenase Inhibitors and Selection and Synthesis of a Development Candidate
Mano, Takashi, Stevens, Rodney W., Ando, Kazuo, Kawai, Makoto, Kawamura, Kiyoshi, Nakao, Kazunari, Okumura, Yoshiyuki, Okumura, Takako, Sakakibara, Minoru, Miyamoto, Kimitaka, Tamura, Tetsuya
Published in Chemical & Pharmaceutical Bulletin (01.08.2005)
Published in Chemical & Pharmaceutical Bulletin (01.08.2005)
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Journal Article
4-[5-Fluoro-3-[4-(2-methyl-1H-imidazol-1-yl)benzyloxy]phenyl]-3,4,5,6- tetrahydro-2H-pyran-4-carboxamide, an Orally Active Inhibitor of 5-Lipoxygenase with Improved Pharmacokinetic and Toxicology Characteristics
Mano, Takashi, Okumura, Yoshiyuki, Sakakibara, Minoru, Okumura, Takako, Tamura, Tetsuya, Miyamoto, Kimitaka, Stevens, Rodney W
Published in Journal of medicinal chemistry (29.01.2004)
Published in Journal of medicinal chemistry (29.01.2004)
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Journal Article
4-[5-Fluoro-3-[4-(2-methyl-1 H -imidazol-1-yl)benzyloxy]phenyl]-3,4,5,6- tetrahydro-2 H -pyran-4-carboxamide, an Orally Active Inhibitor of 5-Lipoxygenase with Improved Pharmacokinetic and Toxicology Characteristics
Mano, Takashi, Okumura, Yoshiyuki, Sakakibara, Minoru, Okumura, Takako, Tamura, Tetsuya, Miyamoto, Kimitaka, Stevens, Rodney W.
Published in Journal of medicinal chemistry (01.01.2004)
Published in Journal of medicinal chemistry (01.01.2004)
Get full text
Journal Article