Establishment of a system to evaluate the therapeutic effect and the dynamics of an investigational drug on ulcerative colitis using human colonic organoids
Nishimura, Ryu, Shirasaki, Tomoaki, Tsuchiya, Kiichiro, Miyake, Yoshihide, Watanabe, Yusuke, Hibiya, Shuji, Watanabe, Sho, Nakamura, Tetsuya, Watanabe, Mamoru
Published in Journal of gastroenterology (01.07.2019)
Published in Journal of gastroenterology (01.07.2019)
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KAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration
Watanabe, Yusuke, Murata, Takahiko, Amakawa, Masahiro, Miyake, Yoshihide, Handa, Tango, Konishi, Katsuhiko, Matsumura, Yasushi, Tanaka, Takuji, Takeuchi, Koji
Published in European journal of pharmacology (05.05.2015)
Published in European journal of pharmacology (05.05.2015)
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Oral administration of EP4-selective agonist KAG-308 suppresses mouse knee osteoarthritis development through reduction of chondrocyte hypertrophy and TNF secretion
Murahashi, Yasutaka, Yano, Fumiko, Chijimatsu, Ryota, Nakamoto, Hideki, Maenohara, Yuji, Amakawa, Masahiro, Miyake, Yoshihide, Yamanaka, Hiroyuki, Iba, Kousuke, Yamashita, Toshihiko, Tanaka, Sakae, Saito, Taku
Published in Scientific reports (30.12.2019)
Published in Scientific reports (30.12.2019)
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A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis
Tietz, Julia, Gunde, Tea, Warmuth, Stefan, Weinert, Christopher, Brock, Matthias, Simonin, Alexandre, Hess, Christian, Johansson, Maria, Spiga, Fabio, Muntwiler, Simone, Wickihalder, Belinda, Mahler, Dana, Diem, Dania, Zeberer, Julia, Heiz, Robin, Flückiger, Naomi, Shiraishi, Noriko, Miyake, Yoshihide, Takahashi, Nobuaki, Fehrholz, Markus, Bertolini, Marta, Lichtlen, Peter, Urech, David, Snell, Daniel
Published in JID innovations (01.03.2024)
Published in JID innovations (01.03.2024)
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A Serine/Threonine Kinase Which Causes Apoptosis-Like Cell Death Interacts with a Calcineurin B-Like Protein Capable of Binding Na+/H+ Exchanger
Matsumoto, Miho, Miyake, Yoshihide, Nagita, Mana, Inoue, Hiroki, Shitakubo, Daiya, Takemoto, Koji, Ohtsuka, Chie, Murakami, Hiroshi, Nakamura, Norihiro, Kanazawa, Hiroshi
Published in Journal of biochemistry (Tokyo) (01.08.2001)
Published in Journal of biochemistry (Tokyo) (01.08.2001)
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Preventive Effects of a Novel Orally-Active EP4-Selective Agonist, KAG-308, in Gastrointestinal Mucosal Injuries
Watanabe, Yusuke, Murata, Takahiko, Amakawa, Masahiro, Miyake, Yoshihide, Handa, Tango, Konishi, Katsuhiko, Matsumura, Yasushi, Tanaka, Takuji, Takeuchi, Koji
Published in Digestive diseases and sciences (23.05.2022)
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Published in Digestive diseases and sciences (23.05.2022)
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IL-4R 및 IL-31에 대한 특이성을 갖는 다중특이적 항체
WARMUTH STEFAN, SHIRAISHI NORIKO, SIMONIN ALEXANDRE, MIYAKE YOSHIHIDE, TIETZ JULIA, HESS CHRISTIAN, GUNDE TEA, JOHANSSON MARIA, ARAKAWA YOSHIO
Year of Publication 29.08.2023
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Year of Publication 29.08.2023
Patent
Kag-308, a Novel Orally Active EP4 Agonist, Ameliorates Mucosal Injury on Endoscopic Examination in a Chronic Colitis Model
Handa, Tango, Amakawa, Masahiro, Miyake, Yoshihide, Takami, Mihoko, Murata, Takahiko, Konishi, Katsuhiko, Matsumura, Yasushi
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
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Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice
Kurokawa, Shigeo, Suda, Masahiro, Okuda, Toshiaki, Miyake, Yoshihide, Matsumura, Yuzuru, Ishimura, Masakazu, Saito, Ryota, Nakamura, Tsutomu
Published in Pulmonary pharmacology & therapeutics (01.10.2010)
Published in Pulmonary pharmacology & therapeutics (01.10.2010)
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Journal Article
Effect of inhaled KP-496, a novel dual antagonist of the cysteinyl leukotriene and thromboxane A 2 receptors, on a bleomycin-induced pulmonary fibrosis model in mice
Kurokawa, Shigeo, Suda, Masahiro, Okuda, Toshiaki, Miyake, Yoshihide, Matsumura, Yuzuru, Ishimura, Masakazu, Saito, Ryota, Nakamura, Tsutomu
Published in Pulmonary pharmacology & therapeutics (2010)
Published in Pulmonary pharmacology & therapeutics (2010)
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MULTISPECIFIC ANTIBODIES HAVING SPECIFICITY FOR IL-4R AND IL-31
JOHANSSON, Maria, SIMONIN, Alexandre, WARMUTH, Stefan, SHIRAISHI, Noriko, TIETZ, Julia, HESS, Christian, ARAKAWA, Yoshio, MIYAKE, Yoshihide, GUNDE, Tea
Year of Publication 01.11.2023
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Year of Publication 01.11.2023
Patent
Multispecific antibodies having specificity for il-4r and il-31
Noriko SHIRAISHI, Maria JOHANSSON, Yoshio ARAKAWA, Tea GUNDE, Stefan WARMUTH, Julia TIETZ, Yoshihide MIYAKE, Alexandre SIMONIN, Christian HESS
Year of Publication 01.07.2023
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Year of Publication 01.07.2023
Patent
MULTISPECIFIC ANTIBODIES HAVING SPECIFICITY FOR IL-4R AND IL-31
JOHANSSON, Maria, SIMONIN, Alexandre, WARMUTH, Stefan, SHIRAISHI, Noriko, TIETZ, Julia, HESS, Christian, ARAKAWA, Yoshio, MIYAKE, Yoshihide, GUNDE, Tea
Year of Publication 29.06.2023
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Year of Publication 29.06.2023
Patent
MULTISPECIFIC ANTIBODIES HAVING SPECIFICITY FOR IL-4R AND IL-31
ARAKAWA, YOSHIO, MIYAKE, YOSHIHIDE, SHIRAISHI, NORIKO, JOHANSSON, MARIA, TIETZ, JULIA, GUNDE, TEA, WARMUTH, STEFAN, SIMONIN, ALEXANDRE, HESS, CHRISTIAN
Year of Publication 30.06.2022
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Year of Publication 30.06.2022
Patent
MULTISPECIFIC ANTIBODIES HAVING SPECIFICITY FOR IL-4R AND IL-31
JOHANSSON, Maria, SIMONIN, Alexandre, WARMUTH, Stefan, SHIRAISHI, Noriko, TIETZ, Julia, HESS, Christian, ARAKAWA, Yoshio, MIYAKE, Yoshihide, GUNDE, Tea
Year of Publication 30.06.2022
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Year of Publication 30.06.2022
Patent
KIF1B 2, Capable of Interacting with CHP, Is Localized to Synaptic Vesicles
Nakamura, N., Miyake, Y., Matsushita, M., Tanaka, S., Inoue, H., Kanazawa, H.
Published in Journal of biochemistry (Tokyo) (01.09.2002)
Published in Journal of biochemistry (Tokyo) (01.09.2002)
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