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A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
Sim, Sarah C, Risinger, Carl, Dahl, Marja-Liisa, Aklillu, Eleni, Christensen, Magnus, Bertilsson, Leif, Ingelman-Sundberg, Magnus
Published in Clinical pharmacology and therapeutics (01.01.2006)
Published in Clinical pharmacology and therapeutics (01.01.2006)
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Cytochrome P450 2C19 loss-of-function polymorphism is a major determinant of clopidogrel responsiveness in healthy subjects
Hulot, Jean-Sébastien, Bura, Alessandra, Villard, Eric, Azizi, Michel, Remones, Véronique, Goyenvalle, Catherine, Aiach, Martine, Lechat, Philippe, Gaussem, Pascale
Published in Blood (01.10.2006)
Published in Blood (01.10.2006)
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Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data
Klein, T E, Altman, R B, Eriksson, N, Gage, B F, Kimmel, S E, Lee, M-T M, Limdi, N A, Page, D, Roden, D M, Wagner, M J, Caldwell, M D, Johnson, J A
Published in The New England journal of medicine (19.02.2009)
Published in The New England journal of medicine (19.02.2009)
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Regulatory variants at 2q33.1 confer schizophrenia risk by modulating distal gene TYW5 expression
Li, Shiwu, Li, Jiao, Liu, Jiewei, Wang, Junyang, Li, Xiaoyan, Huo, Yongxia, Li, Yifan, Liu, Yixing, Li, Ming, Xiao, Xiao, Luo, Xiong-Jian
Published in Brain (London, England : 1878) (18.04.2022)
Published in Brain (London, England : 1878) (18.04.2022)
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Overlapping phenotypes in complex spastic paraplegias SPG11, SPG15, SPG35 and SPG48
Pensato, Viviana, Castellotti, Barbara, Gellera, Cinzia, Pareyson, Davide, Ciano, Claudia, Nanetti, Lorenzo, Salsano, Ettore, Piscosquito, Giuseppe, Sarto, Elisa, Eoli, Marica, Moroni, Isabella, Soliveri, Paola, Lamperti, Elena, Chiapparini, Luisa, Di Bella, Daniela, Taroni, Franco, Mariotti, Caterina
Published in Brain (London, England : 1878) (01.07.2014)
Published in Brain (London, England : 1878) (01.07.2014)
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A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose
Takeuchi, Fumihiko, McGinnis, Ralph, Bourgeois, Stephane, Barnes, Chris, Eriksson, Niclas, Soranzo, Nicole, Whittaker, Pamela, Ranganath, Venkatesh, Kumanduri, Vasudev, McLaren, William, Holm, Lennart, Lindh, Jonatan, Rane, Anders, Wadelius, Mia, Deloukas, Panos
Published in PLoS genetics (01.03.2009)
Published in PLoS genetics (01.03.2009)
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Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans
Gao, Bingsi, Long, Cassandra, Lee, Whayoung, Zhang, Zhongqiang, Gao, Xiaotian, Landsittel, Doug, Ezzelarab, Mohamed, Ayares, David, Huang, Yuliang, Cooper, David K. C., Wang, Yi, Hara, Hidetaka
Published in PloS one (17.07.2017)
Published in PloS one (17.07.2017)
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Common polymorphisms of CYP2C19 and CYP2C9 affect the pharmacokinetic and pharmacodynamic response to clopidogrel but not prasugrel
BRANDT, J. T., CLOSE, S. L., ITURRIA, S. J., PAYNE, C. D., FARID, N. A., ERNEST, C. S., LACHNO, D. R., SALAZAR, D., WINTERS, K. J.
Published in Journal of thrombosis and haemostasis (01.12.2007)
Published in Journal of thrombosis and haemostasis (01.12.2007)
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Knockout of SlALKBH2 weakens the DNA damage repair ability of tomato
Tan, Tingting, Li, Yangyang, Tang, Boyan, Chen, Yating, Chen, Xinru, Xie, Qiaoli, Hu, Zongli, Chen, Guoping
Published in Plant science (Limerick) (01.06.2022)
Published in Plant science (Limerick) (01.06.2022)
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Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells
Burr, Simon, Caldwell, Anna, Chong, Mei, Beretta, Matteo, Metcalf, Stephen, Hancock, Matthew, Arno, Matthew, Balu, Sucharitha, Kropf, Valeria Leon, Mistry, Rajesh K, Shah, Ajay M, Mann, Giovanni E, Brewer, Alison C
Published in Nucleic acids research (16.02.2018)
Published in Nucleic acids research (16.02.2018)
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Mutant combinations of lycopene ɛ‐cyclase and β‐carotene hydroxylase 2 homoeologs increased β‐carotene accumulation in endosperm of tetraploid wheat (Triticum turgidum L.) grains
Yu, Shu, Li, Michelle, Dubcovsky, Jorge, Tian, Li
Published in Plant biotechnology journal (01.03.2022)
Published in Plant biotechnology journal (01.03.2022)
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A genome-wide association study of acenocoumarol maintenance dosage
Teichert, Martina, Eijgelsheim, Mark, Rivadeneira, Fernando, Uitterlinden, Andrė G., van Schaik, Ron H.N., Hofman, Albert, De Smet, Peter A.G.M., van Gelder, Teun, Visser, Loes E., Stricker, Bruno H.Ch
Published in Human molecular genetics (01.10.2009)
Published in Human molecular genetics (01.10.2009)
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A genome-wide association study of pulmonary tuberculosis in Morocco
Grant, A. V., Sabri, A., Abid, A., Abderrahmani Rhorfi, I., Benkirane, M., Souhi, H., Naji Amrani, H., Alaoui-Tahiri, K., Gharbaoui, Y., Lazrak, F., Sentissi, I., Manessouri, M., Belkheiri, S., Zaid, S., Bouraqadi, A., El Amraoui, N., Hakam, M., Belkadi, A., Orlova, M., Boland, A., Deswarte, C., Amar, L., Bustamante, J., Boisson-Dupuis, S., Casanova, J. L., Schurr, E., El Baghdadi, J., Abel, L.
Published in Human genetics (01.03.2016)
Published in Human genetics (01.03.2016)
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Vitamins K and D Status in Stages 3-5 Chronic Kidney Disease
Holden, Rachel M, Morton, A. Ross, Garland, Jocelyn S, Pavlov, Andrey, Day, Andrew G, Booth, Sarah L
Published in Clinical journal of the American Society of Nephrology (01.04.2010)
Published in Clinical journal of the American Society of Nephrology (01.04.2010)
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Genome-wide association study identifies genetic determinants of warfarin responsiveness for Japanese
Cha, Pei-Chieng, Mushiroda, Taisei, Takahashi, Atsushi, Kubo, Michiaki, Minami, Shiro, Kamatani, Naoyuki, Nakamura, Yusuke
Published in Human molecular genetics (01.12.2010)
Published in Human molecular genetics (01.12.2010)
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Influence of CYP2C19 and CYP3A4 gene polymorphisms on clopidogrel responsiveness in healthy subjects
FONTANA, P., HULOT, J.‐S., DE MOERLOOSE, P., GAUSSEM, P.
Published in Journal of thrombosis and haemostasis (01.10.2007)
Published in Journal of thrombosis and haemostasis (01.10.2007)
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Postmortem interval determination using mRNA markers and DNA normalization
Peng, Duo, Lv, Meili, Li, Zhilong, Tian, Huan, Qu, ShengQiu, Jin, Bo, Long, Bing, Liang, Weibo, Zhang, Lin
Published in International journal of legal medicine (01.01.2020)
Published in International journal of legal medicine (01.01.2020)
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