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Correlation of Gene Expression of Ten Drug Efflux Proteins of the ATP-Binding Cassette Transporter Family in Normal Human Jejunum and in Human Intestinal Epithelial Caco-2 Cell Monolayers
Taipalensuu, Jan, Törnblom, Hans, Lindberg, Greger, Einarsson, Curt, Sjöqvist, Folke, Melhus, Håkan, Garberg, Per, Sjöström, Brita, Lundgren, Bo, Artursson, Per
Published in The Journal of pharmacology and experimental therapeutics (01.10.2001)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2001)
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St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4
Dürr, D, Stieger, B, Kullak-Ublick, G A, Rentsch, K M, Steinert, H C, Meier, P J, Fattinger, K
Published in Clinical pharmacology and therapeutics (01.12.2000)
Published in Clinical pharmacology and therapeutics (01.12.2000)
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Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers
Yeh, Rosa F, Gaver, Vincent E, Patterson, Kristine B, Rezk, Naser L, Baxter-Meheux, Faustina, Blake, Michael J, Eron, Jr, Joseph J, Klein, Cheri E, Rublein, John C, Kashuba, Angela D M
Published in Journal of acquired immune deficiency syndromes (1999) (01.05.2006)
Published in Journal of acquired immune deficiency syndromes (1999) (01.05.2006)
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Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects
Nakamura, Tsutomu, Sakaeda, Toshiyuki, Horinouchi, Masanori, Tamura, Takao, Aoyama, Nobuo, Shirakawa, Toshiro, Matsuo, Masafumi, Kasuga, Masato, Okumura, Katsuhiko
Published in Clinical pharmacology and therapeutics (01.04.2002)
Published in Clinical pharmacology and therapeutics (01.04.2002)
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Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans
Mouly, Stéphane, Lown, Kenneth S, Kornhauser, David, Joseph, Jeffrey L, Fiske, William D, Benedek, Irma H, Watkins, Paul B
Published in Clinical pharmacology and therapeutics (01.07.2002)
Published in Clinical pharmacology and therapeutics (01.07.2002)
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Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression
Lown, K S, Bailey, D G, Fontana, R J, Janardan, S K, Adair, C H, Fortlage, L A, Brown, M B, Guo, W, Watkins, P B
Published in The Journal of clinical investigation (15.05.1997)
Published in The Journal of clinical investigation (15.05.1997)
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Effects of polymorphism in promoter region of human CYP2A6 gene (CYP2A69) on expression level of messenger ribonucleic acid and enzymatic activity in vivo and in vitro
Yoshida, Ryoko, Nakajima, Miki, Nishimura, Kiyoko, Tokudome, Shogo, Kwon, Jun-Tack, Yokoi, Tsuyoshi
Published in Clinical pharmacology and therapeutics (01.07.2003)
Published in Clinical pharmacology and therapeutics (01.07.2003)
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In vivo and in vitro induction of human cytochrome P4503A4 by dexamethasone
McCune, J S, Hawke, R L, LeCluyse, E L, Gillenwater, H H, Hamilton, G, Ritchie, J, Lindley, C
Published in Clinical pharmacology and therapeutics (01.10.2000)
Published in Clinical pharmacology and therapeutics (01.10.2000)
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Major Role of Human Liver Microsomal Cytochrome P450 2C9 (CYP2C9) in the Oxidative Metabolism of Celecoxib, a Novel Cyclooxygenase-II Inhibitor
Tang, Cuyue, Shou, Magang, Mei, Qin, Rushmore, Thomas H., Rodrigues, A. David
Published in The Journal of pharmacology and experimental therapeutics (01.05.2000)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2000)
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CHARACTERIZATION OF NOVEL CYP2A6 POLYMORPHIC ALLELES (CYP2A618 AND CYP2A619) THAT AFFECT ENZYMATIC ACTIVITY
Fukami, Tatsuki, Nakajima, Miki, Higashi, Eriko, Yamanaka, Hiroyuki, Sakai, Haruko, McLeod, Howard L., Yokoi, Tsuyoshi
Published in Drug metabolism and disposition (01.08.2005)
Published in Drug metabolism and disposition (01.08.2005)
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Rifampin drastically reduces plasma concentrations and effects of oral midazolam
Backman, J T, Olkkola, K T, Neuvonen, P J
Published in Clinical pharmacology and therapeutics (01.01.1996)
Published in Clinical pharmacology and therapeutics (01.01.1996)
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Wound-induced expression of the ferulate 5-hydroxylase gene in Camptotheca acuminata
Kim, Young Jin, Kim, Dong Gwan, Lee, Sun Hi, Lee, Incheol
Published in Biochimica et biophysica acta (01.02.2006)
Published in Biochimica et biophysica acta (01.02.2006)
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Reduction of CMP- N-acetylneuraminic acid hydroxylase activity in engineered Chinese hamster ovary cells using an antisense-RNA strategy
Chenu, Stephane, Grégoire, Anne, Malykh, Yanina, Visvikis, Athanase, Monaco, Lucia, Shaw, Lee, Schauer, Roland, Marc, Annie, Goergen, Jean-Louis
Published in Biochimica et biophysica acta (23.07.2003)
Published in Biochimica et biophysica acta (23.07.2003)
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Morning spot and 24-hour urinary 6 beta-hydroxycortisol to cortisol ratios: intraindividual variability and correlation under basal conditions and conditions of CYP 3A4 induction
Tran, J Q, Kovacs, S J, McIntosh, T S, Davis, H M, Martin, D E
Published in Journal of clinical pharmacology (01.05.1999)
Published in Journal of clinical pharmacology (01.05.1999)
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Cytochrome p450 3A4 messenger ribonucleic acid induction by rifampin in human peripheral blood mononuclear cells: correlation with alprazolam pharmacokinetics
Gashaw, Isabella, Kirchheiner, Julia, Goldammer, Mark, Bauer, Steffen, Seidemann, Julia, Zoller, Konrad, Mrozikiewicz, Przemyslaw M, Roots, Ivar, Brockmöller, Jürgen
Published in Clinical pharmacology and therapeutics (01.11.2003)
Published in Clinical pharmacology and therapeutics (01.11.2003)
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Sequential ordered fatty acid alpha oxidation and Delta9 desaturation are major determinants of lipid storage and utilization in differentiating adipocytes
Su, Xiong, Han, Xianlin, Yang, Jingyue, Mancuso, David J, Chen, Jeannie, Bickel, Perry E, Gross, Richard W
Published in Biochemistry (Easton) (04.05.2004)
Published in Biochemistry (Easton) (04.05.2004)
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