Daily Fasting Improves Health and Survival in Male Mice Independent of Diet Composition and Calories
Mitchell, Sarah J., Bernier, Michel, Mattison, Julie A., Aon, Miguel A., Kaiser, Tamzin A., Anson, R. Michael, Ikeno, Yuji, Anderson, Rozalyn M., Ingram, Donald K., de Cabo, Rafael
Published in Cell metabolism (08.01.2019)
Published in Cell metabolism (08.01.2019)
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Journal Article
A High-Fat Diet and NAD+ Activate Sirt1 to Rescue Premature Aging in Cockayne Syndrome
Scheibye-Knudsen, Morten, Mitchell, Sarah J., Fang, Evandro F., Iyama, Teruaki, Ward, Theresa, Wang, James, Dunn, Christopher A., Singh, Nagendra, Veith, Sebastian, Hasan-Olive, Md Mahdi, Mangerich, Aswin, Wilson, Mark A., Mattson, Mark P., Bergersen, Linda H., Cogger, Victoria C., Warren, Alessandra, Le Couteur, David G., Moaddel, Ruin, Wilson, David M., Croteau, Deborah L., de Cabo, Rafael, Bohr, Vilhelm A.
Published in Cell metabolism (04.11.2014)
Published in Cell metabolism (04.11.2014)
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Journal Article
impact of low-protein high-carbohydrate diets on aging and lifespan
Le Couteur, David G, Solon-Biet, Samantha, Cogger, Victoria C, Mitchell, Sarah J, Senior, Alistair, de Cabo, Rafael, Raubenheimer, David, Simpson, Stephen J
Published in Cellular and Molecular Life Sciences (01.03.2016)
Published in Cellular and Molecular Life Sciences (01.03.2016)
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Journal Article
Book Review
The SIRT1 Activator SRT1720 Extends Lifespan and Improves Health of Mice Fed a Standard Diet
Mitchell, Sarah J., Martin-Montalvo, Alejandro, Mercken, Evi M., Palacios, Hector H., Ward, Theresa M., Abulwerdi, Gelareh, Minor, Robin K., Vlasuk, George P., Ellis, James L., Sinclair, David A., Dawson, John, Allison, David B., Zhang, Yongqing, Becker, Kevin G., Bernier, Michel, de Cabo, Rafael
Published in Cell reports (Cambridge) (01.03.2014)
Published in Cell reports (Cambridge) (01.03.2014)
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Journal Article
Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to Exercise
Mera, Paula, Laue, Kathrin, Ferron, Mathieu, Confavreux, Cyril, Wei, Jianwen, Galán-Díez, Marta, Lacampagne, Alain, Mitchell, Sarah J., Mattison, Julie A., Chen, Yun, Bacchetta, Justine, Szulc, Pawel, Kitsis, Richard N., de Cabo, Rafael, Friedman, Richard A., Torsitano, Christopher, McGraw, Timothy E., Puchowicz, Michelle, Kurland, Irwin, Karsenty, Gerard
Published in Cell metabolism (14.06.2016)
Published in Cell metabolism (14.06.2016)
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Journal Article
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Schultz, Michael B., Kane, Alice E., Mitchell, Sarah J., MacArthur, Michael R., Warner, Elisa, Vogel, David S., Mitchell, James R., Howlett, Susan E., Bonkowski, Michael S., Sinclair, David A.
Published in Nature communications (15.09.2020)
Published in Nature communications (15.09.2020)
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Journal Article
Dietary Protein to Carbohydrate Ratio and Caloric Restriction: Comparing Metabolic Outcomes in Mice
Solon-Biet, Samantha M., Mitchell, Sarah J., Coogan, Sean C.P., Cogger, Victoria C., Gokarn, Rahul, McMahon, Aisling C., Raubenheimer, David, de Cabo, Rafael, Simpson, Stephen J., Le Couteur, David G.
Published in Cell reports (Cambridge) (16.06.2015)
Published in Cell reports (Cambridge) (16.06.2015)
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Journal Article
Impact of Longevity Interventions on a Validated Mouse Clinical Frailty Index
Kane, Alice E, Hilmer, Sarah N, Boyer, Dawn, Gavin, Kristan, Nines, Dawn, Howlett, Susan E, de Cabo, Rafael, Mitchell, Sarah J
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.03.2016)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.03.2016)
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Journal Article
Macronutrients and caloric intake in health and longevity
Solon-Biet, Samantha M, Mitchell, Sarah J, de Cabo, Rafael, Raubenheimer, David, Le Couteur, David G, Simpson, Stephen J
Published in Journal of endocrinology (01.07.2015)
Published in Journal of endocrinology (01.07.2015)
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Journal Article
A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging
Thomas, Carolin, Erni, Reto, Wu, Jia Yee, Fischer, Fabian, Lamers, Greta, Grigolon, Giovanna, Mitchell, Sarah J., Zarse, Kim, Carreira, Erick M., Ristow, Michael
Published in Nature communications (08.12.2023)
Published in Nature communications (08.12.2023)
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Journal Article
Study of Longitudinal Aging in Mice: Presentation of Experimental Techniques
Palliyaguru, Dushani L, Vieira Ligo Teixeira, Camila, Duregon, Eleonora, di Germanio, Clara, Alfaras, Irene, Mitchell, Sarah J, Navas-Enamorado, Ignacio, Shiroma, Eric J, Studenski, Stephanie, Bernier, Michel, Camandola, Simonetta, Price, Nathan L, Ferrucci, Luigi, de Cabo, Rafael
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2021)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2021)
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Journal Article
Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice
Kip, Peter, Sluiter, Thijs J., MacArthur, Michael R., Tao, Ming, Kruit, Nicky, Mitchell, Sarah J., Jung, Jonathan, Kooijman, Sander, Gorham, Josh, Seidman, Jonathan G., Quax, Paul H. A., Decano, Julius L., Aikawa, Masanori, Ozaki, C. Keith, Mitchell, James R., de Vries, Margreet R.
Published in Nature communications (07.11.2024)
Published in Nature communications (07.11.2024)
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Journal Article
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice
Petr, Michael A, Alfaras, Irene, Krawcyzk, Melissa, Bair, Woei-Nan, Mitchell, Sarah J, Morrell, Christopher H, Studenski, Stephanie A, Price, Nathan L, Fishbein, Kenneth W, Spencer, Richard G, Scheibye-Knudsen, Morten, Lakatta, Edward G, Ferrucci, Luigi, Aon, Miguel A, Bernier, Michel, de Cabo, Rafael
Published in eLife (20.04.2021)
Published in eLife (20.04.2021)
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Journal Article
Pharmacological Inhibition of PI3K Reduces Adiposity and Metabolic Syndrome in Obese Mice and Rhesus Monkeys
Ortega-Molina, Ana, Lopez-Guadamillas, Elena, Mattison, Julie A., Mitchell, Sarah J., Muñoz-Martin, Maribel, Iglesias, Gema, Gutierrez, Vincent M., Vaughan, Kelli L., Szarowicz, Mark D., González-García, Ismael, López, Miguel, Cebrián, David, Martinez, Sonia, Pastor, Joaquin, de Cabo, Rafael, Serrano, Manuel
Published in Cell metabolism (07.04.2015)
Published in Cell metabolism (07.04.2015)
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Journal Article
HuD Regulates Coding and Noncoding RNA to Induce APP→Aβ Processing
Kang, Min-Ju, Abdelmohsen, Kotb, Hutchison, Emmette R., Mitchell, Sarah J., Grammatikakis, Ioannis, Guo, Rong, Noh, Ji Heon, Martindale, Jennifer L., Yang, Xiaoling, Lee, Eun Kyung, Faghihi, Mohammad A., Wahlestedt, Claes, Troncoso, Juan C., Pletnikova, Olga, Perrone-Bizzozero, Nora, Resnick, Susan M., de Cabo, Rafael, Mattson, Mark P., Gorospe, Myriam
Published in Cell reports (Cambridge) (12.06.2014)
Published in Cell reports (Cambridge) (12.06.2014)
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Journal Article
Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging
Huizer-Pajkos, Aniko, Kane, Alice E, Howlett, Susan E, Mach, John, Mitchell, Sarah J, de Cabo, Rafael, Le Couteur, David G, Hilmer, Sarah N
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2016)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2016)
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Journal Article
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Agius, Thomas, Emsley, Raffaella, Lyon, Arnaud, MacArthur, Michael R., Kiesworo, Kevin, Faivre, Anna, Stavart, Louis, Lambelet, Martine, Legouis, David, de Seigneux, Sophie, Golshayan, Déla, Lazeyras, Francois, Yeh, Heidi, Markmann, James F., Uygun, Korkut, Ocampo, Alejandro, Mitchell, Sarah J., Allagnat, Florent, Déglise, Sébastien, Longchamp, Alban
Published in Nature communications (05.02.2024)
Published in Nature communications (05.02.2024)
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Journal Article
Measures of Healthspan as Indices of Aging in Mice-A Recommendation
Richardson, Arlan, Fischer, Kathleen E, Speakman, John R, de Cabo, Rafael, Mitchell, Sarah J, Peterson, Charlotte A, Rabinovitch, Peter, Chiao, Ying A, Taffet, George, Miller, Richard A, Rentería, René C, Bower, James, Ingram, Donald K, Ladiges, Warren C, Ikeno, Yuji, Sierra, Felipe, Austad, Steven N
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2016)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.04.2016)
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Journal Article
The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
Schrötter, Sandra, Yuskaitis, Christopher J., MacArthur, Michael R., Mitchell, Sarah J., Hosios, Aaron M., Osipovich, Maria, Torrence, Margaret E., Mitchell, James R., Hoxhaj, Gerta, Sahin, Mustafa, Manning, Brendan D.
Published in Cell reports (Cambridge) (17.05.2022)
Published in Cell reports (Cambridge) (17.05.2022)
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Journal Article