Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
Fang, Evandro Fei, Scheibye-Knudsen, Morten, Brace, Lear E., Kassahun, Henok, SenGupta, Tanima, Nilsen, Hilde, Mitchell, James R., Croteau, Deborah L., Bohr, Vilhelm A.
Published in Cell (08.05.2014)
Published in Cell (08.05.2014)
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An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
Demaria, Marco, Ohtani, Naoko, Youssef, Sameh A., Rodier, Francis, Toussaint, Wendy, Mitchell, James R., Laberge, Remi-Martin, Vijg, Jan, Van Steeg, Harry, Dollé, Martijn E.T., Hoeijmakers, Jan H.J., de Bruin, Alain, Hara, Eiji, Campisi, Judith
Published in Developmental cell (22.12.2014)
Published in Developmental cell (22.12.2014)
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Journal Article
Endogenous Hydrogen Sulfide Production Is Essential for Dietary Restriction Benefits
Hine, Christopher, Harputlugil, Eylul, Zhang, Yue, Ruckenstuhl, Christoph, Lee, Byung Cheon, Brace, Lear, Longchamp, Alban, Treviño-Villarreal, Jose H., Mejia, Pedro, Ozaki, C. Keith, Wang, Rui, Gladyshev, Vadim N., Madeo, Frank, Mair, William B., Mitchell, James R.
Published in Cell (15.01.2015)
Published in Cell (15.01.2015)
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Journal Article
The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals
Torrence, Margaret E, MacArthur, Michael R, Hosios, Aaron M, Valvezan, Alexander J, Asara, John M, Mitchell, James R, Manning, Brendan D
Published in eLife (01.03.2021)
Published in eLife (01.03.2021)
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Journal Article
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging
Das, Abhirup, Huang, George X., Bonkowski, Michael S., Longchamp, Alban, Li, Catherine, Schultz, Michael B., Kim, Lynn-Jee, Osborne, Brenna, Joshi, Sanket, Lu, Yuancheng, Treviño-Villarreal, Jose Humberto, Kang, Myung-Jin, Hung, Tzong-tyng, Lee, Brendan, Williams, Eric O., Igarashi, Masaki, Mitchell, James R., Wu, Lindsay E., Turner, Nigel, Arany, Zolt, Guarente, Leonard, Sinclair, David A.
Published in Cell (22.03.2018)
Published in Cell (22.03.2018)
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Journal Article
Age and life expectancy clocks based on machine learning analysis of mouse frailty
Schultz, Michael B., Kane, Alice E., Mitchell, Sarah J., MacArthur, Michael R., Warner, Elisa, Vogel, David S., Mitchell, James R., Howlett, Susan E., Bonkowski, Michael S., Sinclair, David A.
Published in Nature communications (15.09.2020)
Published in Nature communications (15.09.2020)
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Journal Article
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Mitchell, Sarah J., Madrigal-Matute, Julio, Scheibye-Knudsen, Morten, Fang, Evandro, Aon, Miguel, González-Reyes, José A., Cortassa, Sonia, Kaushik, Susmita, Gonzalez-Freire, Marta, Patel, Bindi, Wahl, Devin, Ali, Ahmed, Calvo-Rubio, Miguel, Burón, María I., Guiterrez, Vincent, Ward, Theresa M., Palacios, Hector H., Cai, Huan, Frederick, David W., Hine, Christopher, Broeskamp, Filomena, Habering, Lukas, Dawson, John, Beasley, T. Mark, Wan, Junxiang, Ikeno, Yuji, Hubbard, Gene, Becker, Kevin G., Zhang, Yongqing, Bohr, Vilhelm A., Longo, Dan L., Navas, Placido, Ferrucci, Luigi, Sinclair, David A., Cohen, Pinchas, Egan, Josephine M., Mitchell, James R., Baur, Joseph A., Allison, David B., Anson, R. Michael, Villalba, José M., Madeo, Frank, Cuervo, Ana Maria, Pearson, Kevin J., Ingram, Donald K., Bernier, Michel, de Cabo, Rafael
Published in Cell metabolism (14.06.2016)
Published in Cell metabolism (14.06.2016)
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Journal Article
Interventions to Slow Aging in Humans: Are We Ready?
Longo, Valter D., Antebi, Adam, Bartke, Andrzej, Barzilai, Nir, Brown‐Borg, Holly M., Caruso, Calogero, Curiel, Tyler J., Cabo, Rafael, Franceschi, Claudio, Gems, David, Ingram, Donald K., Johnson, Thomas E., Kennedy, Brian K., Kenyon, Cynthia, Klein, Samuel, Kopchick, John J., Lepperdinger, Guenter, Madeo, Frank, Mirisola, Mario G., Mitchell, James R., Passarino, Giuseppe, Rudolph, Karl L., Sedivy, John M., Shadel, Gerald S., Sinclair, David A., Spindler, Stephen R., Suh, Yousin, Vijg, Jan, Vinciguerra, Manlio, Fontana, Luigi
Published in Aging cell (01.08.2015)
Published in Aging cell (01.08.2015)
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Journal Article
Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection
Obaldia, 3rd, Nicanor, Meibalan, Elamaran, Sa, Juliana M, Ma, Siyuan, Clark, Martha A, Mejia, Pedro, Moraes Barros, Roberto R, Otero, William, Ferreira, Marcelo U, Mitchell, James R, Milner, Danny A, Huttenhower, Curtis, Wirth, Dyann F, Duraisingh, Manoj T, Wellems, Thomas E, Marti, Matthias
Published in mBio (08.05.2018)
Published in mBio (08.05.2018)
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Journal Article
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
Hine, Christopher, Kim, Hyo-Jeong, Zhu, Yan, Harputlugil, Eylul, Longchamp, Alban, Matos, Marina Souza, Ramadoss, Preeti, Bauerle, Kevin, Brace, Lear, Asara, John M., Ozaki, C. Keith, Cheng, Sheue-yann, Singha, Subhankar, Ahn, Kyo Han, Kimmelman, Alec, Fisher, Ffolliott M., Pissios, Pavlos, Withers, Dominic J., Selman, Colin, Wang, Rui, Yen, Kelvin, Longo, Valter D., Cohen, Pinchas, Bartke, Andrzej, Kopchick, John J., Miller, Richard, Hollenberg, Anthony N., Mitchell, James R.
Published in Cell metabolism (06.06.2017)
Published in Cell metabolism (06.06.2017)
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Journal Article
The TSC Complex Is Required for the Benefits of Dietary Protein Restriction on Stress Resistance In Vivo
Harputlugil, Eylul, Hine, Christopher, Vargas, Dorathy, Robertson, Lauren, Manning, Brendan D., Mitchell, James R.
Published in Cell reports (Cambridge) (21.08.2014)
Published in Cell reports (Cambridge) (21.08.2014)
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Journal Article
Protein and Calorie Restriction Contribute Additively to Protection from Renal Ischemia Reperfusion Injury Partly via Leptin Reduction in Male Mice
Robertson, Lauren T, Treviño-Villarreal, J Humberto, Mejia, Pedro, Grondin, Yohann, Harputlugil, Eylul, Hine, Christopher, Vargas, Dorathy, Zheng, Hanqiao, Ozaki, C Keith, Kristal, Bruce S, Simpson, Stephen J, Mitchell, James R
Published in The Journal of nutrition (01.08.2015)
Published in The Journal of nutrition (01.08.2015)
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Journal Article
Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging
Das, Abhirup, Huang, George X., Bonkowski, Michael S., Longchamp, Alban, Li, Catherine, Schultz, Michael B., Kim, Lynn-Jee, Osborne, Brenna, Joshi, Sanket, Lu, Yuancheng, Treviño-Villarreal, Jose Humberto, Kang, Myung-Jin, Hung, Tzong-tyng, Lee, Brendan, Williams, Eric O., Igarashi, Masaki, Mitchell, James R., Wu, Lindsay E., Turner, Nigel, Arany, Zolt, Guarente, Leonard, Sinclair, David A.
Published in Cell (07.02.2019)
Published in Cell (07.02.2019)
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Journal Article
Short‐term dietary restriction and fasting precondition against ischemia reperfusion injury in mice
Mitchell, James R., Verweij, Mariëlle, Brand, Karl, Van De Ven, Marieke, Goemaere, Natascha, Van Den Engel, Sandra, Chu, Timothy, Forrer, Flavio, Müller, Cristina, De Jong, Marion, Van IJcken, Wilfred, IJzermans, Jan N. M., Hoeijmakers, Jan H. J., De Bruin, Ron W. F.
Published in Aging cell (01.02.2010)
Published in Aging cell (01.02.2010)
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Journal Article
The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
Schrötter, Sandra, Yuskaitis, Christopher J., MacArthur, Michael R., Mitchell, Sarah J., Hosios, Aaron M., Osipovich, Maria, Torrence, Margaret E., Mitchell, James R., Hoxhaj, Gerta, Sahin, Mustafa, Manning, Brendan D.
Published in Cell reports (Cambridge) (17.05.2022)
Published in Cell reports (Cambridge) (17.05.2022)
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Journal Article
Preoperative dietary restriction reduces intimal hyperplasia and protects from ischemia-reperfusion injury
Mauro, Christine R., MD, Tao, Ming, MD, Yu, Peng, MD, PhD, Treviño-Villerreal, J. Humberto, MD, PhD, Longchamp, Alban, Kristal, Bruce S., PhD, Ozaki, C. Keith, MD, Mitchell, James R., PhD
Published in Journal of vascular surgery (01.02.2016)
Published in Journal of vascular surgery (01.02.2016)
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