New Ref-1/APE1 targeted inhibitors demonstrating improved potency for clinical applications in multiple cancer types
Gampala, Silpa, Moon, Hye-ran, Wireman, Randall, Peil, Jacqueline, Kiran, Sonia, Mitchell, Dana K., Brewster, Kylee, Mang, Henry, Masters, Andi, Bach, Christine, Smith-Kinnamen, Whitney, Doud, Emma H., Rai, Ratan, Mosley, Amber L., Quinney, Sara K., Clapp, D. Wade, Hamdouchi, Chafiq, Wikel, James, Zhang, Chi, Han, Bumsoo, Georgiadis, Millie M., Kelley, Mark R., Fishel, Melissa L.
Published in Pharmacological research (01.03.2024)
Published in Pharmacological research (01.03.2024)
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Neratinib, a pan ERBB/HER inhibitor, restores sensitivity of PTEN -null, BRAFV600E melanoma to BRAF/MEK inhibition
DuBose, Evan, Bevill, Samantha M, Mitchell, Dana K, Sciaky, Noah, Golitz, Brian T, Dixon, Shelley A H, Rhodes, Steven D, Bear, James E, Johnson, Gary L, Angus, Steven P
Published in Frontiers in oncology (16.05.2024)
Published in Frontiers in oncology (16.05.2024)
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Journal Article
SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA‐deficient cells
Chan, Ka‐Kui, Abdul‐Sater, Zahi, Sheth, Aditya, Mitchell, Dana K., Sharma, Richa, Edwards, Donna M., He, Ying, Nalepa, Grzegorz, Rhodes, Steven D., Clapp, D. Wade, Sierra Potchanant, Elizabeth A.
Published in Molecular oncology (01.02.2022)
Published in Molecular oncology (01.02.2022)
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Journal Article
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia
Edwards, Donna M., Mitchell, Dana K., Abdul-Sater, Zahi, Chan, Ka-Kui, Sun, Zejin, Sheth, Aditya, He, Ying, Jiang, Li, Yuan, Jin, Sharma, Richa, Czader, Magdalena, Chin, Pei-Ju, Liu, Yie, de Cárcer, Guillermo, Nalepa, Grzegorz, Broxmeyer, Hal E., Clapp, D. Wade, Sierra Potchanant, Elizabeth A.
Published in Frontiers in oncology (05.11.2021)
Published in Frontiers in oncology (05.11.2021)
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Journal Article
Genetic Testing Guidelines Impact Care in Newborns with Congenital Heart Defects
Durbin, Matthew D., Fairman, Korre, Helvaty, Lindsey R., Huang, Manyan, Li, Ming, Abreu, Daniel, Geddes, Gabrielle C., Helm, Benjamin M., Landis, Benjamin J., McEntire, Alexis, Mitchell, Dana K., Ware, Stephanie M.
Published in The Journal of pediatrics (01.09.2023)
Published in The Journal of pediatrics (01.09.2023)
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Journal Article
Spatial Gene-Expression Profiling Unveils Immuno-oncogenic Programs of NF1-Associated Peripheral Nerve Sheath Tumor Progression
Mitchell, Dana K, Burgess, Breanne, White, Emily E, Smith, Abbi E, Sierra Potchanant, Elizabeth A, Mang, Henry, Hickey, Brooke E, Lu, Qingbo, Qian, Shaomin, Bessler, Waylan, Li, Xiaohong, Jiang, Li, Brewster, Kylee, Temm, Constance, Horvai, Andrew, Albright, Eric A, Fishel, Melissa L, Pratilas, Christine A, Angus, Steven P, Clapp, D Wade, Rhodes, Steven D
Published in Clinical cancer research (01.03.2024)
Published in Clinical cancer research (01.03.2024)
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Journal Article
Correction: Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma
Flint, Alyssa C, Mitchell, Dana K, Angus, Steven P, Smith, Abbi E, Bessler, Waylan, Jiang, Li, Mang, Henry, Li, Xiaohong, Lu, Qingbo, Rodriguez, Brooke, Sandusky, George E, Masters, Andi R, Zhang, Chi, Dang, Pengtao, Koenig, Jenna, Johnson, Gary L, Shen, Weihua, Liu, Jiangang, Aggarwal, Amit, Donoho, Gregory P, Willard, Melinda D, Bhagwat, Shripad V, Clapp, D Wade, Rhodes, Steven D
Published in Clinical cancer research (01.05.2024)
Published in Clinical cancer research (01.05.2024)
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Journal Article
Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma
Flint, Alyssa C, Mitchell, Dana K, Angus, Steven P, Smith, Abbi E, Bessler, Waylan, Jiang, Li, Mang, Henry, Li, Xiaohong, Lu, Qingbo, Rodriguez, Brooke, Sandusky, George E, Masters, Andi R, Zhang, Chi, Dang, Pengtao, Koenig, Jenna, Johnson, Gary L, Shen, Weihua, Liu, Jiangang, Aggarwal, Amit, Donoho, Gregory P, Willard, Melinda D, Bhagwat, Shripad V, Clapp, D Wade, Rhodes, Steven D
Published in Clinical cancer research (01.09.2023)
Published in Clinical cancer research (01.09.2023)
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Journal Article
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 1
Mund, Julie A, Park, SuJung, Smith, Abbi E, He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J, Mitchell, Dana K, Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K, Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D, Clapp, D Wade
Published in The Journal of biological chemistry (17.07.2020)
Published in The Journal of biological chemistry (17.07.2020)
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Journal Article
Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17
Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D. Wade
Published in The Journal of biological chemistry (17.07.2020)
Published in The Journal of biological chemistry (17.07.2020)
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Journal Article
Correction: Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17
Mund, Julie A., Park, SuJung, Smith, Abbi E., He, Yongzheng, Jiang, Li, Hawley, Eric, Roberson, Michelle J., Mitchell, Dana K., Abu-Sultanah, Mohannad, Yuan, Jin, Bessler, Waylan K., Sandusky, George, Chen, Shi, Zhang, Chi, Rhodes, Steven D., Clapp, D.Wade
Published in The Journal of biological chemistry (13.11.2020)
Published in The Journal of biological chemistry (13.11.2020)
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Journal Article
A multicenter cross-sectional study in infants with congenital heart defects demonstrates high diagnostic yield of genetic testing but variable evaluation practices
Durbin, Matthew D., Helvaty, Lindsey R., Li, Ming, Border, William, Fitzgerald-Butt, Sara, Garg, Vidu, Geddes, Gabrielle C., Helm, Benjamin M., Lalani, Seema R., McBride, Kim L., McEntire, Alexis, Mitchell, Dana K., Murali, Chaya N., Wechsler, Stephanie B., Landis, Benjamin J., Ware, Stephanie M.
Published in Genetics in Medicine Open (2023)
Published in Genetics in Medicine Open (2023)
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Journal Article
Rapid Genome Sequencing Shows Diagnostic Utility In Infants With Congenital Heart Defects
Durbin, Matthew D, Helvaty, Lindsey R, Posorske, Alyx, Zhang, Samuel, Huang, Manyan, Li, Ming, Abreu, Daniel, Fairman, Korre, Geddes, Gabrielle C, Helm, Benjamin M, Landis, Benjamin J, McEntire, Alexis, Mitchell, Dana K, Ware, Stephanie M
Published in Research square (20.03.2024)
Published in Research square (20.03.2024)
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Journal Article
Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
Flint, Alyssa C., Mitchell, Dana K., Angus, Steven P., Smith, Abbi E., Bessler, Waylan, Jiang, Li, Mang, Henry, Li, Xiaohong, Lu, Qingbo, Rodriguez, Brooke, Sandusky, George E., Masters, Andi R., Zhang, Chi, Dang, Pengtao, Koenig, Jenna, Johnson, Gary L., Shen, Weihua, Liu, Jiangang, Aggarwal, Amit, Donoho, Gregory P., Willard, Melinda D., Bhagwat, Shripad V., Wade Clapp, D., Rhodes, Steven D.
Published in Clinical cancer research (01.09.2023)
Published in Clinical cancer research (01.09.2023)
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Journal Article
Abstract B072: Pharmacological depletion of fibrinogen suppresses the growth of primary tumors and liver metastasis of pancreatic cancer
Chowdhury, Nayela N, Mitchell, Dana K, Kangro, Kadri, Eldridge, Kierra, Abrahams, Sara, Ferraresso, Francesca, Juang, Lih J, Gampala, Silpa, Brewster, Kylee, Revenko, Alexey, Kastrup, Christian, Territo, Paul R, Clapp, D Wade, Belgodere, Jorge A, Han, Bumsoo, Wolberg, Alisa S, Zhang, Chi, Flick, Matthew J, Fishel, Melissa L
Published in Cancer research (Chicago, Ill.) (15.09.2024)
Published in Cancer research (Chicago, Ill.) (15.09.2024)
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