EMT and Dissemination Precede Pancreatic Tumor Formation
Rhim, Andrew D., Mirek, Emily T., Aiello, Nicole M., Maitra, Anirban, Bailey, Jennifer M., McAllister, Florencia, Reichert, Maximilian, Beatty, Gregory L., Rustgi, Anil K., Vonderheide, Robert H., Leach, Steven D., Stanger, Ben Z.
Published in Cell (20.01.2012)
Published in Cell (20.01.2012)
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Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal Adenocarcinoma
Rhim, Andrew D., Oberstein, Paul E., Thomas, Dafydd H., Mirek, Emily T., Palermo, Carmine F., Sastra, Stephen A., Dekleva, Erin N., Saunders, Tyler, Becerra, Claudia P., Tattersall, Ian W., Westphalen, C. Benedikt, Kitajewski, Jan, Fernandez-Barrena, Maite G., Fernandez-Zapico, Martin E., Iacobuzio-Donahue, Christine, Olive, Kenneth P., Stanger, Ben Z.
Published in Cancer cell (16.06.2014)
Published in Cancer cell (16.06.2014)
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Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver
Fusakio, Michael E, Willy, Jeffrey A, Wang, Yongping, Mirek, Emily T, Al Baghdadi, Rana J T, Adams, Christopher M, Anthony, Tracy G, Wek, Ronald C
Published in Molecular biology of the cell (01.05.2016)
Published in Molecular biology of the cell (01.05.2016)
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Discordant regulation of eIF2 kinase GCN2 and mTORC1 during nutrient stress
Misra, Jagannath, Holmes, Michael J, T. Mirek, Emily, Langevin, Michael, Kim, Hyeong-Geug, Carlson, Kenneth R, Watford, Malcolm, Dong, X Charlie, Anthony, Tracy G, Wek, Ronald C
Published in Nucleic acids research (04.06.2021)
Published in Nucleic acids research (04.06.2021)
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Metabolomic Response of Equine Skeletal Muscle to Acute Fatiguing Exercise and Training
Klein, Dylan J, McKeever, Kenneth H, Mirek, Emily T, Anthony, Tracy G
Published in Frontiers in physiology (18.02.2020)
Published in Frontiers in physiology (18.02.2020)
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GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
Cordova, Ricardo A, Misra, Jagannath, Amin, Parth H, Klunk, Anglea J, Damayanti, Nur P, Carlson, Kenneth R, Elmendorf, Andrew J, Kim, Hyeong-Geug, Mirek, Emily T, Elzey, Bennet D, Miller, Marcus J, Dong, X Charlie, Cheng, Liang, Anthony, Tracy G, Pili, Roberto, Wek, Ronald C, Staschke, Kirk A
Published in eLife (15.09.2022)
Published in eLife (15.09.2022)
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GCN2 is required to increase fibroblast growth factor 21 and maintain hepatic triglyceride homeostasis during asparaginase treatment
Wilson, Gabriel J, Lennox, Brittany A, She, Pengxiang, Mirek, Emily T, Al Baghdadi, Rana J T, Fusakio, Michael E, Dixon, Joseph L, Henderson, Gregory C, Wek, Ronald C, Anthony, Tracy G
Published in American journal of physiology: endocrinology and metabolism (15.02.2015)
Published in American journal of physiology: endocrinology and metabolism (15.02.2015)
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Role of activating transcription factor 4 in the hepatic response to amino acid depletion by asparaginase
Al-Baghdadi, Rana J. T., Nikonorova, Inna A., Mirek, Emily T., Wang, Yongping, Park, Jinhee, Belden, William J., Wek, Ronald C., Anthony, Tracy G.
Published in Scientific reports (28.04.2017)
Published in Scientific reports (28.04.2017)
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Rates of protein synthesis are maintained in brain but reduced in skeletal muscle during dietary sulfur amino acid restriction
Martinez, Wenceslao, Zhang, Qian, Linden, Melissa A, Schacher, Nate, Darvish, Sanna, Mirek, Emily T, Levy, Jordan L, Jonsson, William O, Anthony, Tracy G, Hamilton, Karyn L
Published in Frontiers in aging (24.08.2022)
Published in Frontiers in aging (24.08.2022)
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Time-resolved analysis of amino acid stress identifies eIF2 phosphorylation as necessary to inhibit mTORC1 activity in liver
Nikonorova, Inna A., Mirek, Emily T., Signore, Christina C., Goudie, Michael P., Wek, Ronald C., Anthony, Tracy G.
Published in The Journal of biological chemistry (06.04.2018)
Published in The Journal of biological chemistry (06.04.2018)
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GCN2 drives diurnal patterns in the hepatic integrated stress response and maintains circadian rhythms in whole body metabolism during amino acid insufficiency
Levy, Jordan L, Mirek, Emily T, Rodriguez, Esther M, Tolentino, Maria J, Zalma, Brian A, Roepke, Troy A, Wek, Ronald C, Cao, Ruifeng, Anthony, Tracy G
Published in American journal of physiology: endocrinology and metabolism (01.10.2024)
Published in American journal of physiology: endocrinology and metabolism (01.10.2024)
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GCN2 is required to maintain core body temperature in mice during acute cold
Levy, Jordan L, Mirek, Emily T, Rodriguez, Esther M, Zalma, Brian, Burns, Jeffrey, Jonsson, William O, Sampath, Harini, Staschke, Kirk A, Wek, Ronald C, Anthony, Tracy G
Published in American journal of physiology: endocrinology and metabolism (01.11.2023)
Published in American journal of physiology: endocrinology and metabolism (01.11.2023)
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Physiologic Responses to Dietary Sulfur Amino Acid Restriction in Mice Are Influenced by Atf4 Status and Biological Sex
Jonsson, William O, Margolies, Nicholas S, Mirek, Emily T, Zhang, Qian, Linden, Melissa A, Hill, Cristal M, Link, Christopher, Bithi, Nazmin, Zalma, Brian, Levy, Jordan L, Pettit, Ashley P, Miller, Joshua W, Hine, Christopher, Morrison, Christopher D, Gettys, Thomas W, Miller, Benjamin F, Hamilton, Karyn L, Wek, Ronald C, Anthony, Tracy G
Published in The Journal of nutrition (01.04.2021)
Published in The Journal of nutrition (01.04.2021)
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Targeting GCN2 Regulation of Amino Acid Homeostasis in Prostate Cancer
Cordova, Ricardo, Misra, Jagannath, Amin, Parth H, Damayanti, Nur P, Carlson, Kenneth R, Klunk, Angela J, Mirek, Emily T, Miller, Marcus J, Anthony, Tracy G, Pili, Roberto, Wek, Ronald C, Staschke, Kirk A
Published in The FASEB journal (01.05.2022)
Published in The FASEB journal (01.05.2022)
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Dietary Methionine Restriction Regulates Liver Protein Synthesis and Gene Expression Independently of Eukaryotic Initiation Factor 2 Phosphorylation in Mice
Pettit, Ashley P, Jonsson, William O, Bargoud, Albert R, Mirek, Emily T, Peelor, Frederick F, Wang, Yongping, Gettys, Thomas W, Kimball, Scot R, Miller, Benjamin F, Hamilton, Karyn L, Wek, Ronald C, Anthony, Tracy G
Published in The Journal of nutrition (01.06.2017)
Published in The Journal of nutrition (01.06.2017)
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Circulating metabolite homeostasis achieved through mass action
Li, Xiaoxuan, Hui, Sheng, Mirek, Emily T, Jonsson, William O, Anthony, Tracy G, Lee, Won Dong, Zeng, Xianfeng, Jang, Cholsoon, Rabinowitz, Joshua D
Published in Nature metabolism (01.01.2022)
Published in Nature metabolism (01.01.2022)
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Age modulates liver responses to asparaginase-induced amino acid stress in mice
Nikonorova, Inna A., Zhu, Qiaoqiao, Signore, Christina C., Mirek, Emily T., Jonsson, William O., Kong, Bo, Guo, Grace L., Belden, William J., Anthony, Tracy G.
Published in The Journal of biological chemistry (20.09.2019)
Published in The Journal of biological chemistry (20.09.2019)
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