Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3
Remuiñán, Modesto J, Pérez-Herrán, Esther, Rullás, Joaquín, Alemparte, Carlos, Martínez-Hoyos, María, Dow, David J, Afari, Johnson, Mehta, Nalini, Esquivias, Jorge, Jiménez, Elena, Ortega-Muro, Fátima, Fraile-Gabaldón, María Teresa, Spivey, Vickey L, Loman, Nicholas J, Pallen, Mark J, Constantinidou, Chrystala, Minick, Douglas J, Cacho, Mónica, Rebollo-López, María José, González, Carolina, Sousa, Verónica, Angulo-Barturen, Iñigo, Mendoza-Losana, Alfonso, Barros, David, Besra, Gurdyal S, Ballell, Lluís, Cammack, Nicholas
Published in PloS one (17.04.2013)
Published in PloS one (17.04.2013)
Get full text
Journal Article
An investigation of the absolute configuration of the potent histamine H3 receptor antagonist GT-2331 using vibrational circular dichroism
Minick, Douglas J., Copley, Royston C.B., Szewczyk, Jerzy R., Rutkowske, Randy D., Miller, Luke A.
Published in Chirality (New York, N.Y.) (01.09.2007)
Published in Chirality (New York, N.Y.) (01.09.2007)
Get full text
Journal Article
A concise synthesis of 1,4-dihydro-[1,4]diazepine-5,7-dione, a novel 7-TM receptor ligand core structure with melanocortin receptor agonist activity
Szewczyk, Jerzy R., Laudeman, Chris P., Sammond, Doug M., Villeneuve, Manon, Minick, Douglas J., Grizzle, Mary K., Daniels, Alejandro J., Andrews, John L., Ignar, Diane M.
Published in Bioorganic & medicinal chemistry (01.03.2010)
Published in Bioorganic & medicinal chemistry (01.03.2010)
Get full text
Journal Article
Synthesis and SAR of amino acid-derived heterocyclic progesterone receptor full and partial agonists
Hammond, Marlys, Patterson, Jaclyn R., Manns, Sharada, Hoang, Tram H., Washburn, David G., Trizna, Walter, Glace, Lindsay, Grygielko, Eugene T., Nagilla, Rakesh, Nord, Melanie, Fries, Harvey E., Minick, Douglas J., Laping, Nicholas J., Bray, Jeffrey D., Thompson, Scott K.
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Get full text
Journal Article
Determination of the absolute configuration of (+)- and (-)-N-CBZ-3-fiuoropyrrolidine-3-methanol using vibrational circular dichroism and confirmation of stereochemistry by conversion to (R)-tert-butyl 3-fluoro-3-(((R)-1-phenylethyl)carbamoyl)pyrrolidine-1-carboxylate
Procopiou, Panayiotis A., Hatley, Richard J. D., Lynn, Sean M., Copley, Royston C. B., He, Yanan, Minick, Douglas J.
Published in Tetrahedron: asymmetry (31.12.2016)
Published in Tetrahedron: asymmetry (31.12.2016)
Get full text
Journal Article
Determination of the absolute configuration of (+)- and (−)-N-CBZ-3-fluoropyrrolidine-3-methanol using vibrational circular dichroism and confirmation of stereochemistry by conversion to (R)-tert-butyl 3-fluoro-3-(((R)-1-phenylethyl)carbamoyl)pyrrolidine-1-carboxylate
Procopiou, Panayiotis A., Hatley, Richard J.D., Lynn, Sean M., Copley, Royston C.B., He, Yanan, Minick, Douglas J.
Published in Tetrahedron: asymmetry (31.12.2016)
Published in Tetrahedron: asymmetry (31.12.2016)
Get full text
Journal Article
2-(Anilinomethyl)imidazolines as α1-adrenoceptor agonists: The identification of α1A subtype selective 2'-carboxylic acid esters and amides
BISHOP, Michael J, BERMAN, Judd, SAUSSY, David L, SPEAKE, Jason D, BIGHAM, Eric C, GARRISON, Deanna T, GOBEL, Michael J, HODSON, Stephen J, IRVING, Paul E, LIACOS, James A, MINICK, Douglas J, NAVAS, Frank
Published in Bioorganic & medicinal chemistry letters (01.11.2001)
Published in Bioorganic & medicinal chemistry letters (01.11.2001)
Get full text
Journal Article
2-(Anilinomethyl)imidazolines as α 1-adrenoceptor agonists: the identification of α 1A subtype selective 2′-carboxylic acid esters and amides
Bishop, Michael J, Berman, Judd, Bigham, Eric C, Garrison, Deanna T, Gobel, Michael J, Hodson, Stephen J, Irving, Paul E, Liacos, James A, Minick, Douglas J, Navas, Frank, Saussy, David L, Speake, Jason D
Published in Bioorganic & medicinal chemistry letters (2001)
Published in Bioorganic & medicinal chemistry letters (2001)
Get full text
Journal Article
Synthesis and Identification of a Novel 6,5,6-Tricyclic Lactam
Cooper, Joel P., Cobb, Jeff E., Shearer, Barry G., Minick, Douglas J., Rutkowske, Randy D.
Published in ChemInform (15.07.2003)
Published in ChemInform (15.07.2003)
Get full text
Journal Article