AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity
Lagouge, Marie, Gerhart-Hines, Zachary, Elliott, Peter J, Auwerx, Johan, Feige, Jerome N, Noriega, Lilia, Puigserver, Pere, Milne, Jill C, Cantó, Carles
Published in Nature (London) (23.04.2009)
Published in Nature (London) (23.04.2009)
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SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
Yoshizaki, Takeshi, Schenk, Simon, Imamura, Takeshi, Babendure, Jennie L, Sonoda, Noriyuki, Bae, Eun Ju, Oh, Da Young, Lu, Min, Milne, Jill C, Westphal, Christoph, Bandyopadhyay, Gautam, Olefsky, Jerrold M
Published in American journal of physiology: endocrinology and metabolism (01.03.2010)
Published in American journal of physiology: endocrinology and metabolism (01.03.2010)
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Specific SIRT1 Activation Mimics Low Energy Levels and Protects against Diet-Induced Metabolic Disorders by Enhancing Fat Oxidation
Feige, Jérôme N., Lagouge, Marie, Canto, Carles, Strehle, Axelle, Houten, Sander M., Milne, Jill C., Lambert, Philip D., Mataki, Chikage, Elliott, Peter J., Auwerx, Johan
Published in Cell metabolism (01.11.2008)
Published in Cell metabolism (01.11.2008)
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SIRT1 Exerts Anti-Inflammatory Effects and Improves Insulin Sensitivity in Adipocytes
Yoshizaki, Takeshi, Milne, Jill C., Imamura, Takeshi, Schenk, Simon, Sonoda, Noriyuki, Babendure, Jennie L., Lu, Juu-Chin, Smith, Jesse J., Jirousek, Michael R., Olefsky, Jerrold M.
Published in Molecular and Cellular Biology (01.03.2009)
Published in Molecular and Cellular Biology (01.03.2009)
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Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
Choy, Wendy, Sinclair, David A, Lambert, Philip D, Gagne, David J, Lynch, Amy V, Milne, Jill C, Bemis, Jean E, Boss, Olivier, Perni, Robert B, Schenk, Simon, Carney, David P, Yang, Hongying, Ng, Pui Yee, Iffland, Andre, Smith, Jesse J, Elliott, Peter J, Vu, Chi B, Xie, Roger, Galonek, Heidi, Israelian, Kristine, Lavu, Siva, Medvedik, Oliver, Olefsky, Jerrold M, Disch, Jeremy S, Nunes, Joseph J, Jirousek, Michael R, Westphal, Christoph H, Jin, Lei
Published in Nature (29.11.2007)
Published in Nature (29.11.2007)
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A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange
Liu, Yi, Dentin, Renaud, Chen, Danica, Hedrick, Susan, Ravnskjaer, Kim, Schenk, Simon, Milne, Jill, Meyers, David J., Cole, Phil, III, John Yates, Olefsky, Jerrold, Guarente, Leonard, Montminy, Marc
Published in Nature (London) (13.11.2008)
Published in Nature (London) (13.11.2008)
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Journal Article
protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9
Nakamaru, Yuji, Vuppusetty, Chaitanya, Wada, Hiroo, Milne, Jill C, Ito, Misako, Rossios, Christos, Elliot, Mark, Hogg, James, Kharitonov, Sergei, Goto, Hajime, Bemis, Jean E, Elliott, Peter, Barnes, Peter J, Ito, Kazuhiro
Published in The FASEB journal (01.09.2009)
Published in The FASEB journal (01.09.2009)
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Crystal Structures of Human SIRT3 Displaying Substrate-induced Conformational Changes
Jin, Lei, Wei, Wentao, Jiang, Yaobin, Peng, Hao, Cai, Jianhua, Mao, Chen, Dai, Han, Choy, Wendy, Bemis, Jean E., Jirousek, Michael R., Milne, Jill C., Westphal, Christoph H., Perni, Robert B.
Published in The Journal of biological chemistry (04.09.2009)
Published in The Journal of biological chemistry (04.09.2009)
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Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo
Smith, Jesse J, Kenney, Renée Deehan, Gagne, David J, Frushour, Brian P, Ladd, William, Galonek, Heidi L, Israelian, Kristine, Song, Jeffrey, Razvadauskaite, Giedre, Lynch, Amy V, Carney, David P, Johnson, Robin J, Lavu, Siva, Iffland, Andre, Elliott, Peter J, Lambert, Philip D, Elliston, Keith O, Jirousek, Michael R, Milne, Jill C, Boss, Olivier
Published in BMC systems biology (10.03.2009)
Published in BMC systems biology (10.03.2009)
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Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
Jin, Lei, Galonek, Heidi, Israelian, Kristine, Choy, Wendy, Morrison, Michael, Xia, Yu, Wang, Xiaohong, Xu, Yihua, Yang, Yuecheng, Smith, Jesse J., Hoffmann, Ethan, Carney, David P., Perni, Robert B., Jirousek, Michael R., Bemis, Jean E., Milne, Jill C., Sinclair, David A., Westphal, Christoph H.
Published in Protein science (01.03.2009)
Published in Protein science (01.03.2009)
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Synthesis and Characterization of Fatty Acid Conjugates of Niacin and Salicylic Acid
Vu, Chi B, Bemis, Jean E, Benson, Ericka, Bista, Pradeep, Carney, David, Fahrner, Richard, Lee, Diana, Liu, Feng, Lonkar, Pallavi, Milne, Jill C, Nichols, Andrew J, Picarella, Dominic, Shoelson, Adam, Smith, Jesse, Ting, Amal, Wensley, Allison, Yeager, Maisy, Zimmer, Michael, Jirousek, Michael R
Published in Journal of medicinal chemistry (11.02.2016)
Published in Journal of medicinal chemistry (11.02.2016)
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Discovery of oxazolo[4,5- b]pyridines and related heterocyclic analogs as novel SIRT1 activators
Bemis, Jean E., Vu, Chi B., Xie, Roger, Nunes, Joseph J., Ng, Pui Yee, Disch, Jeremy S., Milne, Jill C., Carney, David P., Lynch, Amy V., Jin, Lei, Smith, Jesse J., Lavu, Siva, Iffland, Andre, Jirousek, Michael R., Perni, Robert B.
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Journal Article
Discovery of Imidazo[1,2-b]thiazole Derivatives as Novel SIRT1 Activators
Vu, Chi B, Bemis, Jean E, Disch, Jeremy S, Ng, Pui Yee, Nunes, Joseph J, Milne, Jill C, Carney, David P, Lynch, Amy V, Smith, Jesse J, Lavu, Siva, Lambert, Philip D, Gagne, David J, Jirousek, Michael R, Schenk, Simon, Olefsky, Jerrold M, Perni, Robert B
Published in Journal of medicinal chemistry (12.03.2009)
Published in Journal of medicinal chemistry (12.03.2009)
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Is it possible to estimate the minimal clinically important treatment effect needed to change practice in preterm birth prevention? Results of an obstetrician survey used to support the design of a trial
Ross, Sue, Milne, Jill, Dwinnell, Shannon, Tang, Selphee, Wood, Stephen
Published in BMC medical research methodology (19.03.2012)
Published in BMC medical research methodology (19.03.2012)
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Journal Article
Thiazole and oxazole peptides: biosynthesis and molecular machinery
Roy, R S, Gehring, A M, Milne, J C, Belshaw, P J, Walsh, C T
Published in Natural product reports (01.04.1999)
Published in Natural product reports (01.04.1999)
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CAT‐2003: A novel sterol regulatory element‐binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E3‐Leiden mice
Zimmer, Michael, Bista, Pradeep, Benson, Ericka L., Lee, Diana Y., Liu, Feng, Picarella, Dominic, Vega, Rick B., Vu, Chi B., Yeager, Maisy, Ding, Min, Liang, Guosheng, Horton, Jay D., Kleemann, Robert, Kooistra, Teake, Morrison, Martine C., Wielinga, Peter Y., Milne, Jill C., Jirousek, Michael R., Nichols, Andrew J.
Published in Hepatology communications (01.06.2017)
Published in Hepatology communications (01.06.2017)
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