Search Results - "Milne, Aileen" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions

by Ewart, Lorna, Milne, Aileen, Adkins, Debbie, Benjamin, Amanda, Bialecki, Russell, Chen, Yafei, Ericsson, Ann-Christin, Gardner, Stacey, Grant, Claire, Lengel, David, Lindgren, Silvana, Lowing, Sarah, Marks, Louise, Moors, Jackie, Oldman, Karen, Pietras, Mark, Prior, Helen, Punton, James, Redfern, Will S., Salmond, Ross, Skinner, Matt, Some, Margareta, Stanton, Andrea, Swedberg, Michael, Finch, John, Valentin, Jean-Pierre
Published in Journal of pharmacological and toxicological methods (01.07.2013)

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Results of a survey on the use of the functional observational battery (FOB) and Irwin tests in central nervous system (CNS) safety pharmacology

Results of a survey on the use of the functional observational battery (FOB) and Irwin tests in central nervous system (CNS) safety pharmacology

by Jackson, Sam, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2019)

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Regulatory respiratory data refinement with reduced animal usage

Regulatory respiratory data refinement with reduced animal usage

by Sladen, Louise, Matheson, Rommel, Norton, Kevin, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2018)

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Loss of Torsade de Points in a rabbit model—The impact of α-chloralose formulation

Loss of Torsade de Points in a rabbit model—The impact of α-chloralose formulation

by Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2009)

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Applying the 3Rs within safety pharmacology assessments for the central nervous system

Applying the 3Rs within safety pharmacology assessments for the central nervous system

by Jackson, Sam, Born, Stephanie, Briscoe, Richard, Milne, Aileen, Tse, Karen, Villegas, Esther Rodriguez, Wilschut, Karlijn, Prior, Helen
Published in Journal of pharmacological and toxicological methods (01.09.2020)

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Neurofunctional test batteries in safety pharmacology – Current and emerging considerations for the drug development process

Neurofunctional test batteries in safety pharmacology – Current and emerging considerations for the drug development process

by Jackson, Samuel J., Authier, Simon, Brohmann, Henning, Goody, Susan M.G., Jones, David, Prior, Helen, Rosch, Anke, Traebert, Martin, Tse, Karen, Valentin, Jean Pierre, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.11.2019)

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Evaluation of minimally invasive blood pressure telemetry devices in conscious Beagle dogs

Evaluation of minimally invasive blood pressure telemetry devices in conscious Beagle dogs

by Skinner, Matt, Milne, Aileen, Grant, Claire, Meyer, Olivier, Stanton, Andrea, Sutherland, Joanne, Moors, Jackie, Bradley, Alys
Published in Journal of pharmacological and toxicological methods (01.09.2016)

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Validation of the minimally invasive blood pressure telemetry technique for use in repeat-dose toxicology studies

Validation of the minimally invasive blood pressure telemetry technique for use in repeat-dose toxicology studies

by Grant, Claire, Stanton, Andrea, Sutherland, Joanne, Billings, Richard, Moors, Jackie, Milne, Aileen, Finch, John
Published in Toxicology letters (10.09.2014)

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Evaluation of the PhysioTel™ Digital M11 cardiovascular telemetry implant in socially housed cynomolgus monkeys up to 16 weeks after surgery

Evaluation of the PhysioTel™ Digital M11 cardiovascular telemetry implant in socially housed cynomolgus monkeys up to 16 weeks after surgery

by Andersen, Ninette K., Meyer, Olivier, Bradley, Alys, Dragsted, Nils, Lassen, Anders B., Sjögren, Ingrid, Larsen, Julie M., Harvey, Warren, Bator, Rastislav, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2017)

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Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies

Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies

by Prior, Helen, Bottomley, Anna, Champéroux, Pascal, Cordes, Jason, Delpy, Eric, Dybdal, Noel, Edmunds, Nick, Engwall, Mike, Foley, Mike, Hoffmann, Michael, Kaiser, Robert, Meecham, Ken, Milano, Stéphane, Milne, Aileen, Nelson, Rick, Roche, Brian, Valentin, Jean-Pierre, Ward, Gemma, Chapman, Kathryn
Published in Journal of pharmacological and toxicological methods (01.09.2016)

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Pair-housed dog telemetry: Animal welfare refinement with early indications of similar study sensitivity

Pair-housed dog telemetry: Animal welfare refinement with early indications of similar study sensitivity

by Prior, Helen, Billing, Richard, Wallace, Ian, South, Marie, Oldman, Karen, Moors, Jackie, Skinner, Matt, Edmunds, Nick, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2015)

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Evaluation of the PhysioTel™ Digital M11 cardiovascular telemetry implant in socially housed cynomolgus monkeys up to 16weeks after surgery

Evaluation of the PhysioTel™ Digital M11 cardiovascular telemetry implant in socially housed cynomolgus monkeys up to 16weeks after surgery

by Andersen, Ninette K., Meyer, Olivier, Bradley, Alys, Dragsted, Nils, Lassen, Anders B., Sjögren, Ingrid, Larsen, Julie M., Harvey, Warren, Bator, Rastislav, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2017)

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Compound X: A preclinical assessment of cardiovascular risk

Compound X: A preclinical assessment of cardiovascular risk

by Byrne, Nichole, Pollock, Jamie, Hartness, Matthew, Macfarlane, Kirsty, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2010)

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Dofetilide, a new class III antiarrhythmic agent, reduces pacing induced heterogeneity of repolarisation in vivo

Dofetilide, a new class III antiarrhythmic agent, reduces pacing induced heterogeneity of repolarisation in vivo

by Gwilt, Michael, King, Robert C, Milne, Aileen A, Solca, Anne M
Published in Cardiovascular research (01.11.1992)

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Understanding the prevalence of inherent cardiac arrhythmias in the beagle dog in the assessment of drug induced changes in the ECG

Understanding the prevalence of inherent cardiac arrhythmias in the beagle dog in the assessment of drug induced changes in the ECG

by Gates, Sotereos C., Macfarlane, Kirsty, Scott-Park, Freda, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.07.2011)

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EVALUATION OF THE PROPENSITY OF NOVEL THERAPEUTIC AGENTS TO INDUCE HISTAMINE RELEASE IN THE GUINEA-PIG SKIN

EVALUATION OF THE PROPENSITY OF NOVEL THERAPEUTIC AGENTS TO INDUCE HISTAMINE RELEASE IN THE GUINEA-PIG SKIN

by Milne, Aileen, Redford, Jane, Laycock, Sarra
Published in Journal of pharmacological and toxicological methods (01.09.2007)

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Is the guinea-pig a suitable model for arterial blood pressure assessment?

Is the guinea-pig a suitable model for arterial blood pressure assessment?

by Byrne, Nichole, Sutton, Anthea, Sharp, Audrey, Gates, Sotereos, Truswell, Claire, Stanton, Andrea, Milne, Aileen, Macfarlane, Kirsty, Laycock, Sarra
Published in Journal of pharmacological and toxicological methods (01.09.2010)

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VALIDATION OF INTRAVENOUS DRUG SELF-ADMINISTRATION IN THE RAT

VALIDATION OF INTRAVENOUS DRUG SELF-ADMINISTRATION IN THE RAT

by Milne, Aileen, Dickinson, Tracey, Shirra, Lisa, Hygate, David, Laycock, Sarra
Published in Journal of pharmacological and toxicological methods (01.09.2007)

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Maximising the utility of an anaesthetised guinea pig model for screening cardiovascular safety: Thioridazine case study

Maximising the utility of an anaesthetised guinea pig model for screening cardiovascular safety: Thioridazine case study

by Gates, Sotereos, Bryne, Nichole, Richardson, Joanne A., Low, Gill, Short, Tracy, South-Wineberg, Belinda, Milne, Aileen
Published in Journal of pharmacological and toxicological methods (01.09.2008)

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Role of the VLA-4 integrin in leucocyte recruitment and bronchial hyperresponsiveness in the guinea-pig

Role of the VLA-4 integrin in leucocyte recruitment and bronchial hyperresponsiveness in the guinea-pig

by Milne, Aileen A.Y., Piper, Priscilla J.
Published in European journal of pharmacology (25.08.1995)

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