Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
Zemek, Rachael M, De Jong, Emma, Chin, Wee Loong, Schuster, Iona S, Fear, Vanessa S, Casey, Thomas H, Forbes, Cath, Dart, Sarah J, Leslie, Connull, Zaitouny, Ayham, Small, Michael, Boon, Louis, Forrest, Alistair R R, Muiri, Daithi O, Degli-Esposti, Mariapia A, Millward, Michael J, Nowak, Anna K, Lassmann, Timo, Bosco, Anthony, Lake, Richard A, Lesterhuis, W Joost
Published in Science translational medicine (17.07.2019)
Published in Science translational medicine (17.07.2019)
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Sensitizing the Tumor Microenvironment to Immune Checkpoint Therapy
Zemek, Rachael M, Chin, Wee Loong, Nowak, Anna K, Millward, Michael J, Lake, Richard A, Lesterhuis, W Joost
Published in Frontiers in immunology (18.02.2020)
Published in Frontiers in immunology (18.02.2020)
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Temporally restricted activation of IFNβ signaling underlies response to immune checkpoint therapy in mice
Zemek, Rachael M., Chin, Wee Loong, Fear, Vanessa S., Wylie, Ben, Casey, Thomas H., Forbes, Cath, Tilsed, Caitlin M., Boon, Louis, Guo, Belinda B., Bosco, Anthony, Forrest, Alistair R. R., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lassmann, Timo, Lesterhuis, W. Joost
Published in Nature communications (19.08.2022)
Published in Nature communications (19.08.2022)
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Changes in expression of PD-L1 on peripheral T cells in patients with melanoma and lung cancer treated with PD-1 inhibitors
Dart, Sarah J., Cook, Alistair M., Millward, Michael J., McDonnell, Alison M., Chin, Wee L., Hakeem, Muhammad U., Meniawy, Tarek M., Bowyer, Samantha E.
Published in Scientific reports (28.07.2021)
Published in Scientific reports (28.07.2021)
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Bilateral murine tumor models for characterizing the response to immune checkpoint blockade
Zemek, Rachael M., Fear, Vanessa S., Forbes, Cath, de Jong, Emma, Casey, Thomas H., Boon, Louis, Lassmann, Timo, Bosco, Anthony, Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost
Published in Nature protocols (01.05.2020)
Published in Nature protocols (01.05.2020)
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Retinoic Acid Induces an IFN-Driven Inflammatory Tumour Microenvironment, Sensitizing to Immune Checkpoint Therapy
Tilsed, Caitlin M, Casey, Thomas H, de Jong, Emma, Bosco, Anthony, Zemek, Rachael M, Salmons, Joanne, Wan, Graeme, Millward, Michael J, Nowak, Anna K, Lake, Richard A, Lesterhuis, Willem Joost
Published in Frontiers in oncology (24.03.2022)
Published in Frontiers in oncology (24.03.2022)
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Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes
Kidman, Joel, Zemek, Rachael M, Sidhom, John-William, Correa, Debora, Principe, Nicola, Sheikh, Fezaan, Fear, Vanessa S, Forbes, Catherine A, Chopra, Abha, Boon, Louis, Zaitouny, Ayham, de Jong, Emma, Holt, Robert A, Jones, Matt, Millward, Michael J, Lassmann, Timo, Forrest, Alistair R R, Nowak, Anna K, Watson, Mark, Lake, Richard A, Lesterhuis, W Joost, Chee, Jonathan
Published in Oncoimmunology (2024)
Published in Oncoimmunology (2024)
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Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy
Chin, Wee Loong, Zemek, Rachael M., Tilsed, Caitlin M., Forrest, Alistair R. R., Fear, Vanessa S., Forbes, Catherine, Boon, Louis, Bosco, Anthony, Guo, Belinda B., Millward, Michael J., Nowak, Anna K., Lake, Richard A., Lesterhuis, W. Joost, Lassmann, Timo
Published in Scientific data (03.05.2024)
Published in Scientific data (03.05.2024)
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Multicenter, Phase II Study of Cetuximab in Combination With Carboplatin in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma
CHAN, Anthony T. C, HSU, Mow-Ming, MUESER, Matthias, AMELLAL, Nadia, XIAO LIN, CHANG, Alex Y, GOH, Boon C, HUI, Edwin P, LIU, Tsang-Wu, MILLWARD, Michael J, HONG, Ruey-Long, WHANG-PENG, Jacqueline, MA, Brigette B. Y, TO, Ka F
Published in Journal of clinical oncology (20.05.2005)
Published in Journal of clinical oncology (20.05.2005)
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Phase I Clinical Trial of Marizomib (NPI-0052) in Patients with Advanced Malignancies Including Multiple Myeloma: Study NPI-0052-102 Final Results
Harrison, Simon J, Mainwaring, Paul, Price, Timothy, Millward, Michael J, Padrik, Peeter, Underhill, Craig R, Cannell, Paul K, Reich, Steven D, Trikha, Mohit, Spencer, Andrew
Published in Clinical cancer research (15.09.2016)
Published in Clinical cancer research (15.09.2016)
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Longitudinal Monitoring of ctDNA in Patients with Melanoma and Brain Metastases Treated with Immune Checkpoint Inhibitors
Lee, Jenny H, Menzies, Alexander M, Carlino, Matteo S, McEvoy, Ashleigh C, Sandhu, Shahneen, Weppler, Alison M, Diefenbach, Russell J, Dawson, Sarah-Jane, Kefford, Richard F, Millward, Michael J, Al-Ogaili, Zeyad, Tra, Thien, Gray, Elin S, Wong, Stephen Q, Scolyer, Richard A, Long, Georgina V, Rizos, Helen
Published in Clinical cancer research (01.08.2020)
Published in Clinical cancer research (01.08.2020)
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A Phase I Study of LY3009120, a Pan-RAF Inhibitor, in Patients with Advanced or Metastatic Cancer
Sullivan, Ryan J, Hollebecque, Antoine, Flaherty, Keith T, Shapiro, Geoffrey I, Rodon Ahnert, Jordi, Millward, Michael J, Zhang, Wei, Gao, Ling, Sykes, Amanda, Willard, Melinda D, Yu, Danni, Schade, Andrew E, Crowe, KrisAnne, Flynn, Daniel L, Kaufman, Michael D, Henry, James R, Peng, Sheng-Bin, Benhadji, Karim A, Conti, Ilaria, Gordon, Michael S, Tiu, Ramon V, Hong, David S
Published in Molecular cancer therapeutics (01.02.2020)
Published in Molecular cancer therapeutics (01.02.2020)
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A Phase II Study of AT-101 (Gossypol) in Chemotherapy-Sensitive Recurrent Extensive-Stage Small Cell Lung Cancer
Baggstrom, Maria Q., Qi, Yingwei, Koczywas, Marianna, Argiris, Athanassios, Johnson, Elizabeth A., Millward, Michael J., Murphy, Sara C., Erlichman, Charles, Rudin, Charles M., Govindan, Ramaswamy
Published in Journal of thoracic oncology (01.10.2011)
Published in Journal of thoracic oncology (01.10.2011)
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Phase IB Trial of the Anti-Cancer Stem Cell DLL4-Binding Agent Demcizumab with Pemetrexed and Carboplatin as First-Line Treatment of Metastatic Non-Squamous NSCLC
McKeage, Mark J., Kotasek, Dusan, Markman, Ben, Hidalgo, Manuel, Millward, Michael J., Jameson, Michael B., Harris, Dean L., Stagg, Robert J., Kapoun, Ann M., Xu, Lu, Hughes, Brett G. M.
Published in Targeted oncology (01.02.2018)
Published in Targeted oncology (01.02.2018)
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PD-L1 on peripheral blood T lymphocytes is prognostic in patients with non-small cell lung cancer (NSCLC) treated with EGFR inhibitors
Meniawy, Tarek M, Lake, Richard A, McDonnell, Alison M, Millward, Michael J, Nowak, Anna K
Published in Lung cancer (Amsterdam, Netherlands) (01.03.2016)
Published in Lung cancer (Amsterdam, Netherlands) (01.03.2016)
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Association of Known Melanoma Risk Factors with Primary Melanoma of the Scalp and Neck
Wood, Renee P, Heyworth, Jane S, McCarthy, Nina S, Mauguen, Audrey, Berwick, Marianne, Thomas, Nancy E, Millward, Michael J, Anton-Culver, Hoda, Cust, Anne E, Dwyer, Terence, Gallagher, Richard P, Gruber, Stephen B, Kanetsky, Peter A, Orlow, Irene, Rosso, Stefano, Moses, Eric K, Begg, Colin B, Ward, Sarah V
Published in Cancer epidemiology, biomarkers & prevention (01.11.2020)
Published in Cancer epidemiology, biomarkers & prevention (01.11.2020)
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An International Phase 2 Study of Pazopanib in Progressive and Metastatic Thyroglobulin Antibody Negative Radioactive Iodine Refractory Differentiated Thyroid Cancer
Bible, Keith C, Menefee, Michael E, Lin, Chia-Chi Josh, Millward, Michael J, Maples, William J, Goh, Boon Cher, Karlin, Nina J, Kane, Madeleine A, Adkins, Douglas R, Molina, Julian R, Donehower, Ross C, Lim, Wan-Teck, Flynn, Patrick J, Richardson, Ronald L, Traynor, Anne M, Rubin, Joseph, LoRusso, Patricia M, Smallridge, Robert C, Burton, Jill K, Suman, Vera J, Kumar, Aditi, Voss, Jessie S, Rumilla, Kandalaria M, Kipp, Benjamin R, Chintakuntlawar, Ashish V, Harris, Pamela, Erlichman, Charles
Published in Thyroid (New York, N.Y.) (01.09.2020)
Published in Thyroid (New York, N.Y.) (01.09.2020)
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A Phase II Study of Intermittent Sunitinib Malate as Second-Line Therapy in Progressive Malignant Pleural Mesothelioma
Nowak, Anna K., Millward, Michael J., Creaney, Jenette, Francis, Roslyn J., Dick, Ian M., Hasani, Arman, van der Schaaf, Agatha, Segal, Amanda, Musk, Arthur W., Byrne, Michael J.
Published in Journal of thoracic oncology (01.09.2012)
Published in Journal of thoracic oncology (01.09.2012)
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