Calcium stabilizes the strongest protein fold
Milles, Lukas F., Unterauer, Eduard M., Nicolaus, Thomas, Gaub, Hermann E.
Published in Nature communications (12.11.2018)
Published in Nature communications (12.11.2018)
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Journal Article
De novo design of knotted tandem repeat proteins
Doyle, Lindsey A., Takushi, Brittany, Kibler, Ryan D., Milles, Lukas F., Orozco, Carolina T., Jones, Jonathan D., Jackson, Sophie E., Stoddard, Barry L., Bradley, Philip
Published in Nature communications (24.10.2023)
Published in Nature communications (24.10.2023)
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Journal Article
Ultrastable cellulosome-adhesion complex tightens under load
Schoeler, Constantin, Malinowska, Klara H., Bernardi, Rafael C., Milles, Lukas F., Jobst, Markus A., Durner, Ellis, Ott, Wolfgang, Fried, Daniel B., Bayer, Edward A., Schulten, Klaus, Gaub, Hermann E., Nash, Michael A.
Published in Nature communications (08.12.2014)
Published in Nature communications (08.12.2014)
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Journal Article
The free energy landscape of retroviral integration
Vanderlinden, Willem, Brouns, Tine, Walker, Philipp U., Kolbeck, Pauline J., Milles, Lukas F., Ott, Wolfgang, Nickels, Philipp C., Debyser, Zeger, Lipfert, Jan
Published in Nature communications (18.10.2019)
Published in Nature communications (18.10.2019)
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Journal Article
Resolving dual binding conformations of cellulosome cohesin-dockerin complexes using single-molecule force spectroscopy
Jobst, Markus A, Milles, Lukas F, Schoeler, Constantin, Ott, Wolfgang, Fried, Daniel B, Bayer, Edward A, Gaub, Hermann E, Nash, Michael A
Published in eLife (31.10.2015)
Published in eLife (31.10.2015)
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Journal Article
Scaffolding protein functional sites using deep learning
Wang, Jue, Lisanza, Sidney, Juergens, David, Tischer, Doug, Watson, Joseph L, Castro, Karla M, Ragotte, Robert, Saragovi, Amijai, Milles, Lukas F, Baek, Minkyung, Anishchenko, Ivan, Yang, Wei, Hicks, Derrick R, Expòsit, Marc, Schlichthaerle, Thomas, Chun, Jung-Ho, Dauparas, Justas, Bennett, Nathaniel, Wicky, Basile I M, Muenks, Andrew, DiMaio, Frank, Correia, Bruno, Ovchinnikov, Sergey, Baker, David
Published in Science (American Association for the Advancement of Science) (22.07.2022)
Published in Science (American Association for the Advancement of Science) (22.07.2022)
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Journal Article
De novo design of protein structure and function with RFdiffusion
Watson, Joseph L., Juergens, David, Bennett, Nathaniel R., Trippe, Brian L., Yim, Jason, Eisenach, Helen E., Ahern, Woody, Borst, Andrew J., Ragotte, Robert J., Milles, Lukas F., Wicky, Basile I. M., Hanikel, Nikita, Pellock, Samuel J., Courbet, Alexis, Sheffler, William, Wang, Jue, Venkatesh, Preetham, Sappington, Isaac, Torres, Susana Vázquez, Lauko, Anna, De Bortoli, Valentin, Mathieu, Emile, Ovchinnikov, Sergey, Barzilay, Regina, Jaakkola, Tommi S., DiMaio, Frank, Baek, Minkyung, Baker, David
Published in Nature (London) (31.08.2023)
Published in Nature (London) (31.08.2023)
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Journal Article
Improving Protein Expression, Stability, and Function with ProteinMPNN
Sumida, Kiera H., Núñez-Franco, Reyes, Kalvet, Indrek, Pellock, Samuel J., Wicky, Basile I. M., Milles, Lukas F., Dauparas, Justas, Wang, Jue, Kipnis, Yakov, Jameson, Noel, Kang, Alex, De La Cruz, Joshmyn, Sankaran, Banumathi, Bera, Asim K., Jiménez-Osés, Gonzalo, Baker, David
Published in Journal of the American Chemical Society (24.01.2024)
Published in Journal of the American Chemical Society (24.01.2024)
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Journal Article
A tethered ligand assay to probe SARS-CoV-2:ACE2 interactions
Bauer, Magnus S, Gruber, Sophia, Hausch, Adina, Gomes, Priscila S F C, Milles, Lukas F, Nicolaus, Thomas, Schendel, Leonard C, Navajas, Pilar López, Procko, Erik, Lietha, Daniel, Melo, Marcelo C R, Bernardi, Rafael C, Gaub, Hermann E, Lipfert, Jan
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2022)
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Journal Article
Single-molecule force stability of the SARS-CoV-2–ACE2 interface in variants-of-concern
Bauer, Magnus S., Gruber, Sophia, Hausch, Adina, Melo, Marcelo C. R., Gomes, Priscila S. F. C., Nicolaus, Thomas, Milles, Lukas F., Gaub, Hermann E., Bernardi, Rafael C., Lipfert, Jan
Published in Nature nanotechnology (01.03.2024)
Published in Nature nanotechnology (01.03.2024)
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Journal Article
Different Vinculin Binding Sites Use the Same Mechanism to Regulate Directional Force Transduction
Kluger, Carleen, Braun, Lukas, Sedlak, Steffen M., Pippig, Diana A., Bauer, Magnus S., Miller, Ken, Milles, Lukas F., Gaub, Hermann E., Vogel, Viola
Published in Biophysical journal (24.03.2020)
Published in Biophysical journal (24.03.2020)
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Journal Article
Hallucination of closed repeat proteins containing central pockets
An, Linna, Hicks, Derrick R., Zorine, Dmitri, Dauparas, Justas, Wicky, Basile I. M., Milles, Lukas F., Courbet, Alexis, Bera, Asim K., Nguyen, Hannah, Kang, Alex, Carter, Lauren, Baker, David
Published in Nature structural & molecular biology (01.11.2023)
Published in Nature structural & molecular biology (01.11.2023)
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Journal Article
From genes to protein mechanics on a chip
Otten, Marcus, Ott, Wolfgang, Jobst, Markus A, Milles, Lukas F, Verdorfer, Tobias, Pippig, Diana A, Nash, Michael A, Gaub, Hermann E
Published in Nature methods (01.11.2014)
Published in Nature methods (01.11.2014)
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Journal Article
DNA-free directed assembly in single-molecule cut-and-paste
Erlich, Katherine R, Sedlak, Steffen M, Jobst, Markus A, Milles, Lukas F, Gaub, Hermann E
Published in Nanoscale (03.01.2019)
Published in Nanoscale (03.01.2019)
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Journal Article
Comparing AFM cantilever stiffness measured using the thermal vibration and the improved thermal vibration methods with that of an SI traceable method based on MEMS
Brand, Uwe, Gao, Sai, Engl, Wolfgang, Sulzbach, Thomas, Stahl, Stefan W, Milles, Lukas F, Nesterov, Vladimir, Li, Zhi
Published in Measurement science & technology (01.03.2017)
Published in Measurement science & technology (01.03.2017)
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Journal Article