Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib
Sun, Yuting, Meyers, Brooke A, Czako, Barbara, Leonard, Paul, Mseeh, Faika, Harris, Angela L, Wu, Qi, Johnson, Sarah, Parker, Connor A, Cross, Jason B, Di Francesco, Maria Emilia, Bivona, Benjamin J, Bristow, Christopher A, Burke, Jason P, Carrillo, Caroline C, Carroll, Christopher L, Chang, Qing, Feng, Ningping, Gao, Guang, Gera, Sonal, Giuliani, Virginia, Huang, Justin K, Jiang, Yongying, Kang, Zhijun, Kovacs, Jeffrey J, Liu, Chiu-Yi, Lopez, Anastasia M, Ma, Xiaoyan, Mandal, Pijus K, McAfoos, Timothy, Miller, Meredith A, Mullinax, Robert A, Peoples, Michael, Ramamoorthy, Vandhana, Seth, Sahil, Spencer, Nakia D, Suzuki, Erika, Williams, Christopher C, Yu, Simon S, Zuniga, Andy M, Draetta, Giulio F, Marszalek, Joseph R, Heffernan, Timothy P, Kohl, Nancy E, Jones, Philip
Published in Cancer research (Chicago, Ill.) (01.11.2020)
Published in Cancer research (Chicago, Ill.) (01.11.2020)
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A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
Wojnarowicz, Paulina M., Lima e Silva, Raquel, Ohnaka, Masayuki, Lee, Sang Bae, Chin, Yvette, Kulukian, Anita, Chang, Sung-Hee, Desai, Bina, Garcia Escolano, Marta, Shah, Riddhi, Garcia-Cao, Marta, Xu, Sijia, Kadam, Rashmi, Goldgur, Yehuda, Miller, Meredith A., Ouerfelli, Ouathek, Yang, Guangli, Arakawa, Tsutomu, Albanese, Steven K., Garland, William A., Stoller, Glenn, Chaudhary, Jaideep, Norton, Larry, Soni, Rajesh Kumar, Philip, John, Hendrickson, Ronald C., Iavarone, Antonio, Dannenberg, Andrew J., Chodera, John D., Pavletich, Nikola, Lasorella, Anna, Campochiaro, Peter A., Benezra, Robert
Published in Cell reports (Cambridge) (01.10.2019)
Published in Cell reports (Cambridge) (01.10.2019)
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Abstract 1102: Integrated approach towards defining mechanism based combinations to guide clinical development of glutaminase inhibitors
Kovacs, Jeffrey J., Spencer, Nakia D., Bristow, Christopher A., Carugo, Alessandro, Giluiani, Virginia, Miller, Meredith A., Harris, Angela, Feng, Ningping, Soth, Michael L., Le, Kang, de Stanchina, Elisa, Rudin, Charles M., Draetta, Giulio, Yap, Timothy A., Jones, Philip, Heffernan, Timothy
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis
Spencer, Nakia D., Bristow, Christopher A., Giulani, Virginia, Miller, Meredith A., Carugo, Alessandro, Harris, Angela L., Minelli, Rosalba, Feng, Ningpeng, Chang, Qing, Soth, Michael J., Le, Kang, Weinstein, John N., Lorenzi, Philip L., Liu, Jinsong, Wang, Wei-Lien, Yap, Timothy A., Draetta, Giulio, Jones, Philip, Heffernan, Timothy P., Kovacs, Jeffrey J.
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Allosteric SHP2 inhibitor IACS-13909 overcomes EGFR-dependent and EGFR-independent resistance mechanisms towards osimertinib
Sun, Yuting, Meyers, Brooke A., Czako, Barbara, Leonard, Paul, Mseeh, Faika, Harris, Angela L., Wu, Qi, Johnson, Sarah, Parker, Connor A., Cross, Jason B., Francesco, Maria Emilia Di, Bivona, Benjamin J., Bristow, Christopher A., Burke, Jason P., Carrillo, Caroline C., Carroll, Christopher L., Chang, Qing, Feng, Ningping, Gao, Guang, Gera, Sonal, Giuliani, Virginia, Huang, Justin K., Jiang, Yongying, Kang, Zhijun, Kovacs, Jeffrey J., Liu, Chiu-Yi, Lopez, Anastasia M., Ma, Xiaoyan, Mandal, Pijus K., McAfoos, Timothy, Miller, Meredith A., Mullinax, Robert A., Peoples, Michael, Ramamoorthy, Vandhana, Seth, Sahil, Spencer, Nakia D., Suzuki, Erika, Williams, Christopher C., Yu, Simon S., Zuniga, Andy M., Draetta, Giulio F., Marszalek, Joseph R., Heffernan, Timothy P., Kohl, Nancy E., Jones, Philip
Published in Cancer research (Chicago, Ill.) (14.09.2020)
Published in Cancer research (Chicago, Ill.) (14.09.2020)
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Abstract 4975: A small molecule pan Id protein antagonist shows strong antitumor activity
Wojnarowicz, Paulina M., Desai, Bina, Chin, Yvette, Lee, Sang Bae, Garcia-Cao, Marta, Ouerfelli, Ouathek, Yang, Guangli, Xu, Sijia, Goldgur, Yehuda, Miller, Meredith A., Chaudhary, Jaideep, Garland, William A., Albanese, Steven K., Soni, Rajesh, Philip, John, Norton, Larry, Rosen, Neal, Hendrickson, Ronald C., Zhou, Xi Kathy, Iavarone, Antonio, Dannenberg, Andrew J., Chodera, John D., Pavletich, Nikola, Lasorella, Anna, Benezra, Robert
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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