Plant Process for the Preparation of Cinchona Alkaloid-Based Thiourea Catalysts
Wang, Yi, Milkiewicz, Karen L, Kaufman, Mildred L, He, Linli, Landmesser, Nelson G, Levy, Daniel V, Allwein, Shawn P, Christie, Michael A, Olsen, Mark A, Neville, Christopher J, Muthukumaran, Kannan
Published in Organic process research & development (17.03.2017)
Published in Organic process research & development (17.03.2017)
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Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Grasberger, Bruce L, Lu, Tianbao, Schubert, Carsten, Parks, Daniel J, Carver, Theodore E, Koblish, Holly K, Cummings, Maxwell D, LaFrance, Louis V, Milkiewicz, Karen L, Calvo, Raul R, Maguire, Diane, Lattanze, Jennifer, Franks, Carol F, Zhao, Shuyuan, Ramachandren, Kannan, Bylebyl, Gwendolyn R, Zhang, Marie, Manthey, Carl L, Petrella, Eugene C, Pantoliano, Michael W, Deckman, Ingrid C, Spurlino, John C, Maroney, Anna C, Tomczuk, Bruce E, Molloy, Christopher J, Bone, Roger F
Published in Journal of medicinal chemistry (24.02.2005)
Published in Journal of medicinal chemistry (24.02.2005)
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A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5-a]pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of CEP-33779
Dugan, Benjamin J, Gingrich, Diane E, Mesaros, Eugen F, Milkiewicz, Karen L, Curry, Matthew A, Zulli, Allison L, Dobrzanski, Pawel, Serdikoff, Cynthia, Jan, Mahfuza, Angeles, Thelma S, Albom, Mark S, Mason, Jennifer L, Aimone, Lisa D, Meyer, Sheryl L, Huang, Zeqi, Wells-Knecht, Kevin J, Ator, Mark A, Ruggeri, Bruce A, Dorsey, Bruce D
Published in Journal of medicinal chemistry (14.06.2012)
Published in Journal of medicinal chemistry (14.06.2012)
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Development of a Process Route to the FAK/ALK Dual Inhibitor TEV-37440
Allwein, Shawn P, Mowrey, Dale R, Petrillo, Daniel E, Reif, James J, Purohit, Vikram C, Milkiewicz, Karen L, Bakale, Roger P, Christie, Michael A, Olsen, Mark A, Neville, Christopher J, Gilmartin, Gregory J
Published in Organic process research & development (19.05.2017)
Published in Organic process research & development (19.05.2017)
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Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation in vitro and sensitize tumors to doxorubicin in vivo
Koblish, Holly K, Zhao, Shuyuan, Franks, Carol F, Donatelli, Robert R, Tominovich, Rose M, LaFrance, Louis V, Leonard, Kristi A, Gushue, Joan M, Parks, Daniel J, Calvo, Raul R, Milkiewicz, Karen L, Marugán, Juan José, Raboisson, Pierre, Cummings, Maxwell D, Grasberger, Bruce L, Johnson, Dana L, Lu, Tianbao, Molloy, Christopher J, Maroney, Anna C
Published in Molecular cancer therapeutics (01.01.2006)
Published in Molecular cancer therapeutics (01.01.2006)
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1,4-Benzodiazepine-2,5-diones as small molecule antagonists of the HDM2–p53 interaction: discovery and SAR
Parks, Daniel J., LaFrance, Louis V., Calvo, Raul R., Milkiewicz, Karen L., Gupta, Varsha, Lattanze, Jennifer, Ramachandren, Kannan, Carver, Theodore E., Petrella, Eugene C., Cummings, Maxwell D., Maguire, Diane, Grasberger, Bruce L., Lu, Tianbao
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Synthesis and structure–activity relationships of 1,2,3,4-tetrahydropyrido[2,3- b]pyrazines as potent and selective inhibitors of the anaplastic lymphoma kinase
Milkiewicz, Karen L., Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Cheng, Mangeng, Ghose, Arup K., Roemmele, Renee C., Theroff, Jay P., Underiner, Ted L., Zificsak, Craig A., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry (15.06.2010)
Published in Bioorganic & medicinal chemistry (15.06.2010)
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7-Fluoroindazoles as Potent and Selective Inhibitors of Factor Xa
Lee, Yu-Kai, Parks, Daniel J, Lu, Tianbao, Thieu, Tho V, Markotan, Thomas, Pan, Wenxi, McComsey, David F, Milkiewicz, Karen L, Crysler, Carl S, Ninan, Nisha, Abad, Marta C, Giardino, Edward C, Maryanoff, Bruce E, Damiano, Bruce P, Player, Mark R
Published in Journal of medicinal chemistry (24.01.2008)
Published in Journal of medicinal chemistry (24.01.2008)
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Fused bicyclic derivatives of 2,4-diaminopyrimidine as c-Met inhibitors
Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Husten, Jean, Lisko, Joseph G., McHugh, Robert J., Milkiewicz, Karen L., Murthy, Seetha, Ott, Gregory R., Theroff, Jay P., Tripathy, Rabindranath, Underiner, Ted L., Zificsak, Craig A., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
Published in Bioorganic & medicinal chemistry letters (01.01.2011)
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2,7-Pyrrolo[2,1- f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation
Weinberg, Linda R., Albom, Mark S., Angeles, Thelma S., Breslin, Henry J., Gingrich, Diane E., Huang, Zeqi, Lisko, Joseph G., Mason, Jennifer L., Milkiewicz, Karen L., Thieu, Tho V., Underiner, Ted L., Wells, Gregory J., Wells-Knecht, Kevin J., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
Published in Bioorganic & medicinal chemistry letters (15.12.2011)
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Enhanced pharmacokinetic properties of 1,4-benzodiazepine-2,5-dione antagonists of the HDM2-p53 protein–protein interaction through structure-based drug design
Parks, Daniel J., LaFrance, Louis V., Calvo, Raul R., Milkiewicz, Karen L., José Marugán, Juan, Raboisson, Pierre, Schubert, Carsten, Koblish, Holly K., Zhao, Shuyuan, Franks, Carol F., Lattanze, Jennifer, Carver, Theodore E., Cummings, Maxwell D., Maguire, Diane, Grasberger, Bruce L., Maroney, Anna C., Lu, Tianbao
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
Published in Bioorganic & medicinal chemistry letters (15.06.2006)
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Improvement in oral bioavailability of 2,4-diaminopyrimidine c-Met inhibitors by incorporation of a 3-amidobenzazepin-2-one group
Milkiewicz, Karen L., Aimone, Lisa D., Albom, Mark S., Angeles, Thelma S., Chang, Hong, Grobelny, Jennifer V., Husten, Jean, LoSardo, Christine, Miknyoczki, Sheila, Murthy, Seetha, Rolon-Steele, Damaris, Underiner, Ted L., Weinberg, Linda R., Worrell, Candace S., Zeigler, Kelli S., Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry (01.11.2011)
Published in Bioorganic & medicinal chemistry (01.11.2011)
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Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases
Zificsak, Craig A., Gingrich, Diane E., Breslin, Henry J., Dunn, Derek D., Milkiewicz, Karen L., Theroff, Jay P., Thieu, Tho V., Underiner, Ted L., Weinberg, Linda R., Aimone, Lisa D., Albom, Mark S., Mason, Jennifer L., Saville, Lisa, Husten, Jean, Angeles, Thelma S., Finn, James P., Jan, Mahfuza, O’Kane, Teresa M., Dobrzanski, Pawel, Dorsey, Bruce D.
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Substituted 1,4-Benzodiazepine-2,5-diones as α-Helix Mimetic Antagonists of the HDM2-p53 Protein-Protein Interaction
Cummings, Maxwell D., Schubert, Carsten, Parks, Daniel J., Calvo, Raul R., LaFrance, Louis V., Lattanze, Jennifer, Milkiewicz, Karen L., Lu, Tianbao
Published in Chemical biology & drug design (01.03.2006)
Published in Chemical biology & drug design (01.03.2006)
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PREPARATION AND USES OF 1,2,4-TRIAZOLO [1,5A] PYRIDINE DERIVATIVES
GINGRICH DIANE E, DUGAN BENJAMIN J, MESAROS EUGEN F, MILKIEWICZ KAREN L, CURRY MATTHEW A, DORSEY BRUCE D
Year of Publication 08.05.2012
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Year of Publication 08.05.2012
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