Application of a gut–liver-on-a-chip device and mechanistic modelling to the quantitative in vitro pharmacokinetic study of mycophenolate mofetil
Milani, Nicoló, Parrott, Neil, Ortiz Franyuti, Daniela, Godoy, Patricio, Galetin, Aleksandra, Gertz, Michael, Fowler, Stephen
Published in Lab on a chip (26.07.2022)
Published in Lab on a chip (26.07.2022)
Get full text
Journal Article
From Experiments to a Fast Easy-to-Use Computational Methodology to Predict Human Aldehyde Oxidase Selectivity and Metabolic Reactions
Cruciani, Gabriele, Milani, Nicolò, Benedetti, Paolo, Lepri, Susan, Cesarini, Lucia, Baroni, Massimo, Spyrakis, Francesca, Tortorella, Sara, Mosconi, Edoardo, Goracci, Laura
Published in Journal of medicinal chemistry (11.01.2018)
Published in Journal of medicinal chemistry (11.01.2018)
Get full text
Journal Article
Structure–metabolism relationships in human-AOX: Chemical insights from a large database of aza-aromatic and amide compounds
Lepri, Susan, Ceccarelli, Martina, Milani, Nicolò, Tortorella, Sara, Cucco, Andrea, Valeri, Aurora, Goracci, Laura, Brink, Andreas, Cruciani, Gabriele
Published in Proceedings of the National Academy of Sciences - PNAS (18.04.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (18.04.2017)
Get full text
Journal Article
Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies
Docci, Luca, Milani, Nicolò, Ramp, Thomas, Romeo, Andrea A, Godoy, Patricio, Franyuti, Daniela Ortiz, Krähenbühl, Stephan, Gertz, Michael, Galetin, Aleksandra, Parrott, Neil, Fowler, Stephen
Published in Lab on a chip (15.03.2022)
Published in Lab on a chip (15.03.2022)
Get full text
Journal Article
In silico modeling and simulation of organ‐on‐a‐chip systems to support data analysis and a priori experimental design
Milani, Nicoló, Parrott, Neil, Galetin, Aleksandra, Fowler, Stephen, Gertz, Michael
Published in CPT: pharmacometrics and systems pharmacology (01.04.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.04.2024)
Get full text
Journal Article
Application of a gut-liver-on-a-chip device and mechanistic modelling to the quantitative pharmacokinetic study of mycophenolate mofetil
Milani, Nicoló, Parrott, Neil, Ortiz Franyuti, Daniela, Godoy, Patricio, Galetin, Aleksandra, Gertz, Michael, Fowler, Stephen
Published in Lab on a chip (26.07.2022)
Published in Lab on a chip (26.07.2022)
Get full text
Journal Article
Use of Phenotypically Poor Metabolizer Individual Donor Human Liver Microsomes To Identify Selective Substrates of UGT2B10
Milani, Nicolo, Qiu, NaHong, Molitor, Birgit, Badée, Justine, Cruciani, Gabriele, Fowler, Stephen
Published in Drug metabolism and disposition (01.03.2020)
Published in Drug metabolism and disposition (01.03.2020)
Get full text
Journal Article