Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells
Appelberg, Sofia, Gupta, Soham, Svensson Akusjärvi, Sara, Ambikan, Anoop T., Mikaeloff, Flora, Saccon, Elisa, Végvári, Ákos, Benfeitas, Rui, Sperk, Maike, Ståhlberg, Marie, Krishnan, Shuba, Singh, Kamal, Penninger, Josef M., Mirazimi, Ali, Neogi, Ujjwal
Published in Emerging microbes & infections (01.01.2020)
Published in Emerging microbes & infections (01.01.2020)
Get full text
Journal Article
Nucleoside-Modified mRNA Vaccines Protect IFNAR -/- Mice against Crimean-Congo Hemorrhagic Fever Virus Infection
Appelberg, Sofia, John, Lijo, Pardi, Norbert, Végvári, Ákos, Bereczky, Sándor, Ahlén, Gustaf, Monteil, Vanessa, Abdurahman, Samir, Mikaeloff, Flora, Beattie, Mitchell, Tam, Ying, Sällberg, Matti, Neogi, Ujjwal, Weissman, Drew, Mirazimi, Ali
Published in Journal of virology (09.02.2022)
Published in Journal of virology (09.02.2022)
Get full text
Journal Article
Utility of Proteomics in Emerging and Re-Emerging Infectious Diseases Caused by RNA Viruses
Sperk, Maike, van Domselaar, Robert, Rodriguez, Jimmy Esneider, Mikaeloff, Flora, Sá Vinhas, Beatriz, Saccon, Elisa, Sönnerborg, Anders, Singh, Kamal, Gupta, Soham, Végvári, Ákos, Neogi, Ujjwal
Published in Journal of proteome research (06.11.2020)
Published in Journal of proteome research (06.11.2020)
Get full text
Journal Article
Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells
Chen, Xi, Saccon, Elisa, Appelberg, K. Sofia, Mikaeloff, Flora, Rodriguez, Jimmy Esneider, Vinhas, Beatriz Sá, Frisan, Teresa, Végvári, Ákos, Mirazimi, Ali, Neogi, Ujjwal, Gupta, Soham
Published in Cell death discovery (18.05.2021)
Published in Cell death discovery (18.05.2021)
Get full text
Journal Article
A high-risk gut microbiota configuration associates with fatal hyperinflammatory immune and metabolic responses to SARS-CoV-2
Albrich, Werner C., Ghosh, Tarini Shankar, Ahearn-Ford, Sinead, Mikaeloff, Flora, Lunjani, Nonhlanhla, Forde, Brian, Suh, Noémie, Kleger, Gian-Reto, Pietsch, Urs, Frischknecht, Manuel, Garzoni, Christian, Forlenza, Rossella, Horgan, Mary, Sadlier, Corinna, Negro, Tommaso Rochat, Pugin, Jérôme, Wozniak, Hannah, Cerny, Andreas, Neogi, Ujjwal, O'Toole, Paul W., O'Mahony, Liam
Published in Gut microbes (2022)
Published in Gut microbes (2022)
Get full text
Journal Article
Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
Mikaeloff, Flora, Gelpi, Marco, Benfeitas, Rui, Knudsen, Andreas D, Vestad, Beate, Høgh, Julie, Hov, Johannes R, Benfield, Thomas, Murray, Daniel, Giske, Christian G, Mardinoglu, Adil, Trøseid, Marius, Nielsen, Susanne D, Neogi, Ujjwal
Published in eLife (2023)
Published in eLife (2023)
Get full text
Journal Article
Cell-type-resolved quantitative proteomics map of interferon response against SARS-CoV-2
Saccon, Elisa, Chen, Xi, Mikaeloff, Flora, Rodriguez, Jimmy Esneider, Szekely, Laszlo, Vinhas, Beatriz Sá, Krishnan, Shuba, Byrareddy, Siddappa N., Frisan, Teresa, Végvári, Ákos, Mirazimi, Ali, Neogi, Ujjwal, Gupta, Soham
Published in iScience (21.05.2021)
Published in iScience (21.05.2021)
Get full text
Journal Article
Cytotoxic Lymphocytes Target HIV-1 Gag Through Granzyme M-Mediated Cleavage
Saccon, Elisa, Mikaeloff, Flora, Figueras Ivern, Pol, Végvári, Ákos, Sönnerborg, Anders, Neogi, Ujjwal, van Domselaar, Robert
Published in Frontiers in immunology (19.04.2021)
Published in Frontiers in immunology (19.04.2021)
Get full text
Journal Article
In silico and in vitro studies reveal complement system drives coagulation cascade in SARS-CoV-2 pathogenesis
Tiwari, Ritudhwaj, Mishra, Anurag R., Mikaeloff, Flora, Gupta, Soham, Mirazimi, Ali, Byrareddy, Siddappa N., Neogi, Ujjwal, Nayak, Debasis
Published in Computational and structural biotechnology journal (01.01.2020)
Published in Computational and structural biotechnology journal (01.01.2020)
Get full text
Journal Article
Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status
Sperk, Maike, Mikaeloff, Flora, Svensson-Akusjärvi, Sara, Krishnan, Shuba, Ponnan, Sivasankaran Munusamy, Ambikan, Anoop T., Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal
Published in iScience (19.02.2021)
Published in iScience (19.02.2021)
Get full text
Journal Article
Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling
Akusjärvi, Sara Svensson, Ambikan, Anoop T., Krishnan, Shuba, Gupta, Soham, Sperk, Maike, Végvári, Ákos, Mikaeloff, Flora, Healy, Katie, Vesterbacka, Jan, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal
Published in iScience (21.01.2022)
Published in iScience (21.01.2022)
Get full text
Journal Article
Trans cohort metabolic reprogramming towards glutaminolysis in long-term successfully treated HIV-infection
Mikaeloff, Flora, Svensson Akusjärvi, Sara, Ikomey, George Mondinde, Krishnan, Shuba, Sperk, Maike, Gupta, Soham, Magdaleno, Gustavo Daniel Vega, Escós, Alejandra, Lyonga, Emilia, Okomo, Marie Claire, Tagne, Claude Tayou, Babu, Hemalatha, Lorson, Christian L., Végvári, Ákos, Banerjea, Akhil C., Kele, Julianna, Hanna, Luke Elizabeth, Singh, Kamal, de Magalhães, João Pedro, Benfeitas, Rui, Neogi, Ujjwal
Published in Communications biology (11.01.2022)
Published in Communications biology (11.01.2022)
Get full text
Journal Article
Distinct Metabolic Profile Associated with a Fatal Outcome in COVID-19 Patients during the Early Epidemic in Italy
Saccon, Elisa, Bandera, Alessandra, Sciumè, Mariarita, Mikaeloff, Flora, Lashari, Abid A, Aliberti, Stefano, Sachs, Michael C, Billi, Filippo, Blasi, Francesco, Gabriel, Erin E, Costantino, Giorgio, De Roberto, Pasquale, Krishnan, Shuba, Gori, Andrea, Peyvandi, Flora, Scudeller, Luigia, Canetta, Ciro, Lorson, Christian L, Valenti, Luca, Singh, Kamal, Baldini, Luca, Fracchiolla, Nicola Stefano, Neogi, Ujjwal
Published in Microbiology spectrum (31.10.2021)
Published in Microbiology spectrum (31.10.2021)
Get full text
Journal Article
Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication
Krishnan, Shuba, Nordqvist, Hampus, Ambikan, Anoop T., Gupta, Soham, Sperk, Maike, Svensson-Akusjärvi, Sara, Mikaeloff, Flora, Benfeitas, Rui, Saccon, Elisa, Ponnan, Sivasankaran Munusamy, Rodriguez, Jimmy Esneider, Nikouyan, Negin, Odeh, Amani, Ahlén, Gustaf, Asghar, Muhammad, Sällberg, Matti, Vesterbacka, Jan, Nowak, Piotr, Végvári, Ákos, Sönnerborg, Anders, Treutiger, Carl Johan, Neogi, Ujjwal
Published in Molecular & cellular proteomics (01.01.2021)
Published in Molecular & cellular proteomics (01.01.2021)
Get full text
Journal Article
Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment
Svensson Akusjärvi, Sara, Krishnan, Shuba, Ambikan, Anoop T., Mikaeloff, Flora, Munusamy Ponnan, Sivasankaran, Vesterbacka, Jan, Lourda, Magda, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal
Published in AIDS (London) (09.02.2023)
Published in AIDS (London) (09.02.2023)
Get full text
Journal Article
Coordinated pyruvate kinase activity is crucial for metabolic adaptation and cell survival during mitochondrial dysfunction
Zhou, Xiaoshan, Mikaeloff, Flora, Curbo, Sophie, Zhao, Qian, Kuiper, Raoul, Végvári, Ákos, Neogi, Ujjwal, Karlsson, Anna
Published in Human molecular genetics (13.10.2021)
Published in Human molecular genetics (13.10.2021)
Get full text
Journal Article
Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist
Sperk, Maike, Ambikan, Anoop T, Ray, Shilpa, Singh, Kamal, Mikaeloff, Flora, Diez, Rafael Ceña, Narayanan, Ashwathy, Vesterbacka, Jan, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal
Published in Journal of virology (25.08.2021)
Published in Journal of virology (25.08.2021)
Get full text
Journal Article
Functional SARS-CoV-2 cross-reactive CD4 + T cells established in early childhood decline with age
Humbert, Marion, Olofsson, Anna, Wullimann, David, Niessl, Julia, Hodcroft, Emma B, Cai, Curtis, Gao, Yu, Sohlberg, Ebba, Dyrdak, Robert, Mikaeloff, Flora, Neogi, Ujjwal, Albert, Jan, Malmberg, Karl-Johan, Lund-Johansen, Fridtjof, Aleman, Soo, Björkhem-Bergman, Linda, Jenmalm, Maria C, Ljunggren, Hans-Gustaf, Buggert, Marcus, Karlsson, Annika C
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (21.03.2023)
Get full text
Journal Article
Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment
Svensson Akusjärvi, Sara, Krishnan, Shuba, Ambikan, Anoop T., Mikaeloff, Flora, Munusamy Ponnan, Sivasankaran, Vesterbacka, Jan, Lourda, Magda, Nowak, Piotr, Sönnerborg, Anders, Neogi, Ujjwal
Published in AIDS (London) (01.06.2023)
Published in AIDS (London) (01.06.2023)
Get full text
Journal Article
Transcriptomics age acceleration in prolonged treated HIV infection
Mikaeloff, Flora, Gelpi, Marco, Escos, Alejandra, Knudsen, Andreas D, Høgh, Julie, Benfield, Thomas, de Magalhães, João Pedro, Nielsen, Susanne D, Neogi, Ujjwal
Published in Aging cell (01.10.2023)
Published in Aging cell (01.10.2023)
Get full text
Journal Article