Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation
Ochalek, Anna, Mihalik, Balázs, Avci, Hasan X, Chandrasekaran, Abinaya, Téglási, Annamária, Bock, István, Giudice, Maria Lo, Táncos, Zsuzsanna, Molnár, Kinga, László, Lajos, Nielsen, Jørgen E, Holst, Bjørn, Freude, Kristine, Hyttel, Poul, Kobolák, Julianna, Dinnyés, András
Published in Alzheimer's research & therapy (01.12.2017)
Published in Alzheimer's research & therapy (01.12.2017)
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Journal Article
Optical waveguide lightmode spectroscopic techniques for investigating membrane-bound ion channel activities
Székács, Inna, Kaszás, Nóra, Gróf, Pál, Erdélyi, Katalin, Szendrő, István, Mihalik, Balázs, Pataki, Agnes, Antoni, Ferenc A, Madarász, Emilia
Published in PloS one (10.12.2013)
Published in PloS one (10.12.2013)
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Journal Article
The Nervous System Relevance of the Calcium Sensing Receptor in Health and Disease
Giudice, Maria Lo, Mihalik, Balázs, Dinnyés, András, Kobolák, Julianna
Published in Molecules (Basel, Switzerland) (12.07.2019)
Published in Molecules (Basel, Switzerland) (12.07.2019)
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Journal Article
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods
Krebs, Alice, van Vugt-Lussenburg, Barbara M. A., Waldmann, Tanja, Albrecht, Wiebke, Boei, Jan, ter Braak, Bas, Brajnik, Maja, Braunbeck, Thomas, Brecklinghaus, Tim, Busquet, Francois, Dinnyes, Andras, Dokler, Joh, Dolde, Xenia, Exner, Thomas E., Fisher, Ciarán, Fluri, David, Forsby, Anna, Hengstler, Jan G., Holzer, Anna-Katharina, Janstova, Zofia, Jennings, Paul, Kisitu, Jaffar, Kobolak, Julianna, Kumar, Manoj, Limonciel, Alice, Lundqvist, Jessica, Mihalik, Balázs, Moritz, Wolfgang, Pallocca, Giorgia, Ulloa, Andrea Paola Cediel, Pastor, Manuel, Rovida, Costanza, Sarkans, Ugis, Schimming, Johannes P., Schmidt, Bela Z., Stöber, Regina, Strassfeld, Tobias, van de Water, Bob, Wilmes, Anja, van der Burg, Bart, Verfaillie, Catherine M., von Hellfeld, Rebecca, Vrieling, Harry, Vrijenhoek, Nanette G., Leist, Marcel
Published in Archives of toxicology (01.07.2020)
Published in Archives of toxicology (01.07.2020)
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Journal Article
Loop F of the GABA A receptor alpha subunit governs GABA potency
Pálvölgyi, Adrienn, Móricz, Krisztina, Pataki, Ágnes, Mihalik, Balázs, Gigler, Gábor, Megyeri, Katalin, Udvari, Szabolcs, Gacsályi, István, Antoni, Ferenc A
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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Journal Article
Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABA A receptors
Mihalik, Balázs, Pálvölgyi, Adrienn, Bogár, Ferenc, Megyeri, Katalin, Ling, István, Barkóczy, József, Bartha, Ferenc, Martinek, Tamás A, Gacsályi, István, Antoni, Ferenc A
Published in European journal of pharmacology (05.03.2017)
Published in European journal of pharmacology (05.03.2017)
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Journal Article
A novel GABA(A) alpha 5 receptor inhibitor with therapeutic potential
Ling, István, Mihalik, Balázs, Etherington, Lori-An, Kapus, Gábor, Pálvölgyi, Adrienn, Gigler, Gábor, Kertész, Szabolcs, Gaál, Attila, Pallagi, Katalin, Kiricsi, Péter, Szabó, Éva, Szénási, Gábor, Papp, Lilla, Hársing, László G, Lévay, György, Spedding, Michael, Lambert, Jeremy J, Belelli, Delia, Barkóczy, József, Volk, Balázs, Simig, Gyula, Gacsályi, István, Antoni, Ferenc A
Published in European journal of pharmacology (05.10.2015)
Published in European journal of pharmacology (05.10.2015)
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Journal Article
Selective inhibition of extra-synaptic α5-GABAA receptors by S44819, a new therapeutic agent
Etherington, Lori-An, Mihalik, Balázs, Pálvölgyi, Adrienn, Ling, István, Pallagi, Katalin, Kertész, Szabolcs, Varga, Péter, Gunn, Ben G., Brown, Adam R., Livesey, Matthew R., Monteiro, Olivia, Belelli, Delia, Barkóczy, József, Spedding, Michael, Gacsályi, István, Antoni, Ferenc A., Lambert, Jeremy J.
Published in Neuropharmacology (01.10.2017)
Published in Neuropharmacology (01.10.2017)
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Journal Article
Human in vitro neurotoxicology enabled by hiPSC-derived neurons
Kobolák, Julianna, Mihalik, Balázs, Téglási, Annamária, Xu, Wenming, Shi, Jianyang, Sun, Qun, Dinnyés, András
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2017)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2017)
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Journal Article
Loop F of the GABAA receptor alpha subunit governs GABA potency
Pálvölgyi, Adrienn, Móricz, Krisztina, Pataki, Ágnes, Mihalik, Balázs, Gigler, Gábor, Megyeri, Katalin, Udvari, Szabolcs, Gacsályi, István, Antoni, Ferenc A.
Published in Neuropharmacology (01.01.2018)
Published in Neuropharmacology (01.01.2018)
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Journal Article
Loop-F of the α-subunit determines the pharmacologic profile of novel competitive inhibitors of GABAA receptors
Mihalik, Balázs, Pálvölgyi, Adrienn, Bogár, Ferenc, Megyeri, Katalin, Ling, István, Barkóczy, József, Bartha, Ferenc, Martinek, Tamás A., Gacsályi, István, Antoni, Ferenc A.
Published in European journal of pharmacology (05.03.2017)
Published in European journal of pharmacology (05.03.2017)
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Journal Article
A novel GABAA alpha 5 receptor inhibitor with therapeutic potential
Ling, István, Mihalik, Balázs, Etherington, Lori-An, Kapus, Gábor, Pálvölgyi, Adrienn, Gigler, Gábor, Kertész, Szabolcs, Gaál, Attila, Pallagi, Katalin, Kiricsi, Péter, Szabó, Éva, Szénási, Gábor, Papp, Lilla, Hársing, László G., Lévay, György, Spedding, Michael, Lambert, Jeremy J., Belelli, Delia, Barkóczy, József, Volk, Balázs, Simig, Gyula, Gacsályi, István, Antoni, Ferenc A.
Published in European journal of pharmacology (05.10.2015)
Published in European journal of pharmacology (05.10.2015)
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Journal Article
Requirement of membrane‐proximal amino acids in the carboxyl‐terminal tail for expression of the rat AT1a angiotensin receptor
Gáborik, Zsuzsanna, Mihalik, Balázs, Jayadev, Suman, Jagadeesh, Gowraganahalli, Catt, Kevin J., Hunyady, László
Published in FEBS letters (29.05.1998)
Published in FEBS letters (29.05.1998)
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Journal Article
Selective inhibition of extra-synaptic α5-GABA A receptors by S44819, a new therapeutic agent
Etherington, Lori-An, Mihalik, Balázs, Pálvölgyi, Adrienn, Ling, István, Pallagi, Katalin, Kertész, Szabolcs, Varga, Péter, Gunn, Ben G, Brown, Adam R, Livesey, Matthew R, Monteiro, Olivia, Belelli, Delia, Barkóczy, József, Spedding, Michael, Gacsályi, István, Antoni, Ferenc A, Lambert, Jeremy J
Published in Neuropharmacology (01.10.2017)
Published in Neuropharmacology (01.10.2017)
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Journal Article
Endocytosis of the AT 1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region
Mihalik, Balázs, Gáborik, Zsuzsanna, Várnai, Péter, Clark, Adrian J.L, Catt, Kevin J, Hunyady, László
Published in The international journal of biochemistry & cell biology (2003)
Published in The international journal of biochemistry & cell biology (2003)
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Journal Article
Endocytosis of the AT1A angiotensin receptor is independent of ubiquitylation of its cytoplasmic serine/threonine-rich region
Mihalik, Balázs, Gáborik, Zsuzsanna, Várnai, Péter, Clark, Adrian J L, Catt, Kevin J, Hunyady, László
Published in The international journal of biochemistry & cell biology (01.06.2003)
Published in The international journal of biochemistry & cell biology (01.06.2003)
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Journal Article
Dependence of AT1 Angiotensin Receptor Function on Adjacent Asparagine Residues in the Seventh Transmembrane Helix
Hunyady, L, Ji, H, Jagadeesh, G, Zhang, M, Gáborik, Z, Mihalik, B, Catt, K J
Published in Molecular pharmacology (01.08.1998)
Published in Molecular pharmacology (01.08.1998)
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Journal Article
Extracellular signal-regulated kinase and the small GTP-binding protein p21Rac1 are involved in the regulation of gene transcription by angiotensin II
Huszár, T, Mucsi, I, Antus, B, Terebessy, T, Jeney, C, Masszi, A, Hunyady, L, Mihalik, B, Goldberg, H J, Thekkumkara, T J, Rosivall, L
Published in Experimental nephrology (01.03.2001)
Published in Experimental nephrology (01.03.2001)
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Journal Article
Agonist-Induced Phosphorylation of the Angiotensin AT 1a Receptor Is Localized to a Serine/Threonine-Rich Region of Its Cytoplasmic Tail
Smith, Roger D., Hunyady, László, Olivares-Reyes, J. Alberto, Mihalik, Balázs, Jayadev, Suman, Catt, Kevin J.
Published in Molecular pharmacology (01.12.1998)
Published in Molecular pharmacology (01.12.1998)
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