New Pharmacological Approaches Using Polyphenols on the Physiopathology of Neuropathic Pain
Boadas-Vaello, Pere, Vela, Jose Miguel, Verdu, Enrique
Published in Current drug targets (01.01.2017)
Published in Current drug targets (01.01.2017)
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Journal Article
Comprehensive Preclinical Assessment of Sensory, Functional, Motivational-Affective, and Neurochemical Outcomes in Neuropathic Pain: The Case of the Sigma‑1 Receptor
de la Puente, Beatriz, Zamanillo, Daniel, Romero, Luz, Carceller, Alicia, Vela, José Miguel, Merlos, Manuel, Portillo-Salido, Enrique
Published in ACS pharmacology & translational science (08.04.2022)
Published in ACS pharmacology & translational science (08.04.2022)
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Journal Article
Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic‐guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model
Cendrós, Josep‐Maria, Salichs, Marta, Encina, Gregorio, Vela, Jose Miguel, Homedes, Josep M.
Published in Veterinary medicine and science (01.01.2022)
Published in Veterinary medicine and science (01.01.2022)
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Journal Article
5-HT6 receptor and cognition
Codony, Xabier, Vela, Jose Miguel, Ramírez, Maria Javier
Published in Current opinion in pharmacology (01.02.2011)
Published in Current opinion in pharmacology (01.02.2011)
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Journal Article
The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats
Gris, Georgia, Portillo-Salido, Enrique, Aubel, Bertrand, Darbaky, Yassine, Deseure, Kristof, Vela, José Miguel, Merlos, Manuel, Zamanillo, Daniel
Published in Scientific reports (18.04.2016)
Published in Scientific reports (18.04.2016)
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Journal Article
Co-crystal of tramadol-celecoxib: preclinical and clinical evaluation of a novel analgesic
Gascon, Neus, Almansa, Carmen, Merlos, Manuel, Miguel Vela, José, Encina, Gregorio, Morte, Adelaida, Smith, Kevin, Plata-Salamán, Carlos
Published in Expert opinion on investigational drugs (04.05.2019)
Published in Expert opinion on investigational drugs (04.05.2019)
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Journal Article
Sigma 1 receptor: A new therapeutic target for pain
Zamanillo, Daniel, Romero, Luz, Merlos, Manuel, Vela, José Miguel
Published in European journal of pharmacology (15.09.2013)
Published in European journal of pharmacology (15.09.2013)
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Journal Article
Selective inhibition of cyclooxygenase‐2 by enflicoxib, its enantiomers and its main metabolites in vitro in canine blood
Solà, Josep, Menargues, Àngel, Homedes, Josep, Salichs, Marta, Álvarez, Inés, Romero, Luz, Vela, José Miguel
Published in Journal of veterinary pharmacology and therapeutics (01.05.2022)
Published in Journal of veterinary pharmacology and therapeutics (01.05.2022)
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Journal Article
WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity
Christmann, Ute, Garriga, Lourdes, Llorente, Ana Virginia, Díaz, José Luis, Pascual, Rosalía, Bordas, Magda, Dordal, Albert, Porras, Mónica, Yeste, Sandra, Reinoso, Raquel F., Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (13.06.2024)
Published in Journal of medicinal chemistry (13.06.2024)
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Journal Article
Resilience to Pain-Related Depression in σ1 Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes
de la Puente, Beatriz, Zamanillo, Daniel, Romero, Luz, Carceller, Alicia, Vela, José Miguel, Merlos, Manuel, Portillo-Salido, Enrique
Published in ACS chemical neuroscience (04.10.2023)
Published in ACS chemical neuroscience (04.10.2023)
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Journal Article
Neuroprotective Effects of Sigma 1 Receptor Ligands on Motoneuron Death after Spinal Root Injury in Mice
Gaja-Capdevila, Núria, Hernández, Neus, Zamanillo, Daniel, Vela, Jose Miguel, Merlos, Manuel, Navarro, Xavier, Herrando-Grabulosa, Mireia
Published in International journal of molecular sciences (28.06.2021)
Published in International journal of molecular sciences (28.06.2021)
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Journal Article
Synthesis and Biological Evaluation of the 1‑Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4‑{2-[5-Methyl-1-(naphthalen-2-yl)‑1H‑pyrazol-3-yloxy]ethyl}morpholine (S1RA, E‑52862)
Díaz, José Luis, Cuberes, Rosa, Berrocal, Joana, Contijoch, Montserrat, Christmann, Ute, Fernández, Ariadna, Port, Adriana, Holenz, Jörg, Buschmann, Helmut, Laggner, Christian, Serafini, Maria Teresa, Burgueño, Javier, Zamanillo, Daniel, Merlos, Manuel, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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Journal Article
Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain
Merlos, Manuel, Burgueño, Javier, Portillo-Salido, Enrique, Plata-Salamán, Carlos Ramón, Vela, José Miguel
Published in Advances in experimental medicine and biology (01.01.2017)
Published in Advances in experimental medicine and biology (01.01.2017)
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Book Chapter
Journal Article
GABA, but not opioids, mediates the anti-hyperalgesic effects of 5-HT7 receptor activation in rats suffering from neuropathic pain
Viguier, Florent, Michot, Benoît, Kayser, Valérie, Bernard, Jean-François, Vela, José-Miguel, Hamon, Michel, Bourgoin, Sylvie
Published in Neuropharmacology (01.11.2012)
Published in Neuropharmacology (01.11.2012)
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Journal Article