Sigma 1 receptor: A new therapeutic target for pain
Zamanillo, Daniel, Romero, Luz, Merlos, Manuel, Vela, José Miguel
Published in European journal of pharmacology (15.09.2013)
Published in European journal of pharmacology (15.09.2013)
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Journal Article
WLB-87848, a Selective σ1 Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity
Christmann, Ute, Garriga, Lourdes, Llorente, Ana Virginia, Díaz, José Luis, Pascual, Rosalía, Bordas, Magda, Dordal, Albert, Porras, Mónica, Yeste, Sandra, Reinoso, Raquel F., Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (13.06.2024)
Published in Journal of medicinal chemistry (13.06.2024)
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Journal Article
Resilience to Pain-Related Depression in σ1 Receptor Knockout Mice Is Associated with the Reversal of Pain-Induced Brain Changes in Affect-Related Genes
de la Puente, Beatriz, Zamanillo, Daniel, Romero, Luz, Carceller, Alicia, Vela, José Miguel, Merlos, Manuel, Portillo-Salido, Enrique
Published in ACS chemical neuroscience (04.10.2023)
Published in ACS chemical neuroscience (04.10.2023)
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Journal Article
Synthesis and Biological Evaluation of the 1‑Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4‑{2-[5-Methyl-1-(naphthalen-2-yl)‑1H‑pyrazol-3-yloxy]ethyl}morpholine (S1RA, E‑52862)
Díaz, José Luis, Cuberes, Rosa, Berrocal, Joana, Contijoch, Montserrat, Christmann, Ute, Fernández, Ariadna, Port, Adriana, Holenz, Jörg, Buschmann, Helmut, Laggner, Christian, Serafini, Maria Teresa, Burgueño, Javier, Zamanillo, Daniel, Merlos, Manuel, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (11.10.2012)
Published in Journal of medicinal chemistry (11.10.2012)
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Journal Article
Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain
Merlos, Manuel, Burgueño, Javier, Portillo-Salido, Enrique, Plata-Salamán, Carlos Ramón, Vela, José Miguel
Published in Advances in experimental medicine and biology (01.01.2017)
Published in Advances in experimental medicine and biology (01.01.2017)
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Book Chapter
Journal Article
5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice
BRENCHAT, Alex, ROMERO, Luz, MIGUEL VELA, José, GARCIA, Monica, PUJOL, Marta, BURGUENO, Javier, TORRENS, Antoni, HAMON, Michel, BAEYENS, José Manuel, BUSCHMANN, Helmut, ZAMANILLO, Daniel
Published in Pain (Amsterdam) (01.02.2009)
Published in Pain (Amsterdam) (01.02.2009)
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Journal Article
Long-Lasting Nociplastic Pain Modulation by Repeated Administration of Sigma-1 Receptor Antagonist BD1063 in Fibromyalgia-like Mouse Models
Álvarez-Pérez, Beltrán, Bagó-Mas, Anna, Deulofeu, Meritxell, Vela, José Miguel, Merlos, Manuel, Verdú, Enrique, Boadas-Vaello, Pere
Published in International journal of molecular sciences (08.10.2022)
Published in International journal of molecular sciences (08.10.2022)
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Journal Article
Sigma-1 receptor antagonism as opioid adjuvant strategy: Enhancement of opioid antinociception without increasing adverse effects
Vidal-Torres, Alba, de la Puente, Beatriz, Rocasalbas, Maria, Touriño, Clara, Andreea Bura, Simona, Fernández-Pastor, Begoña, Romero, Luz, Codony, Xavier, Zamanillo, Daniel, Buschmann, Helmut, Merlos, Manuel, Manuel Baeyens, José, Maldonado, Rafael, Vela, José Miguel
Published in European journal of pharmacology (05.07.2013)
Published in European journal of pharmacology (05.07.2013)
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Journal Article
Transient Reflexive Pain Responses and Chronic Affective Nonreflexive Pain Responses Associated with Neuroinflammation Processes in Both Spinal and Supraspinal Structures in Spinal Cord-Injured Female Mice
Castany, Sílvia, Bagó-Mas, Anna, Vela, José Miguel, Verdú, Enrique, Bretová, Karolina, Svobodová, Viktorie, Dubový, Petr, Boadas-Vaello, Pere
Published in International journal of molecular sciences (16.01.2023)
Published in International journal of molecular sciences (16.01.2023)
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Journal Article
Co-crystals as a new approach to multimodal analgesia and the treatment of pain
Almansa, Carmen, Frampton, Christopher S, Vela, Jose Miguel, Whitelock, Steve, Plata-Salaman, Carlos R
Published in Journal of Pain Research (01.09.2019)
Published in Journal of Pain Research (01.09.2019)
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Journal Article
Book Review
Role of Sigma-1 Receptors in Paclitaxel-Induced Neuropathic Pain in Mice
Nieto, Francisco Rafael, Cendán, Cruz Miguel, Sánchez-Fernández, Cristina, Cobos, Enrique José, Entrena, José Manuel, Tejada, Miguel Angel, Zamanillo, Daniel, Vela, José Miguel, Baeyens, José Manuel
Published in The journal of pain (01.11.2012)
Published in The journal of pain (01.11.2012)
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Journal Article
Mite diversity (Acari: Tetranychidae, Tydeidae, Iolinidae, Phytoseiidae) and within-tree distribution in citrus orchards in southern Spain, with special reference to Eutetranychus orientalis
Vela, José Miguel, Wong, Eva, Jaques, Josep A., Ledesma, Claudio, Boyero, Juan Ramón
Published in Experimental & applied acarology (01.10.2017)
Published in Experimental & applied acarology (01.10.2017)
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Journal Article
Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury
Puente, Beatriz de la, Nadal, Xavier, Portillo-Salido, Enrique, Sánchez-Arroyos, Ricard, Ovalle, Sergio, Palacios, Gabriel, Muro, Asunción, Romero, Luz, Entrena, José Manuel, Baeyens, José Manuel, López-García, José Antonio, Maldonado, Rafael, Zamanillo, Daniel, Vela, José Miguel
Published in Pain (Amsterdam) (01.10.2009)
Published in Pain (Amsterdam) (01.10.2009)
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Journal Article
Synthesis and Structure–Activity Relationship Study of a New Series of Selective σ1 Receptor Ligands for the Treatment of Pain: 4‑Aminotriazoles
Díaz, José Luis, Christmann, Ute, Fernández, Ariadna, Torrens, Antoni, Port, Adriana, Pascual, Rosalia, Álvarez, Inés, Burgueño, Javier, Monroy, Xavier, Montero, Ana, Balada, Ariadna, Vela, José Miguel, Almansa, Carmen
Published in Journal of medicinal chemistry (12.03.2015)
Published in Journal of medicinal chemistry (12.03.2015)
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Journal Article
Predicting the Antinociceptive Efficacy of σ1 Receptor Ligands by a Novel Receptor Fluorescence Resonance Energy Transfer (FRET) Based Biosensor
Gómez-Soler, Maricel, Fernández-Dueñas, Víctor, Portillo-Salido, Enrique, Pérez, Pilar, Zamanillo, Daniel, Vela, José Miguel, Burgueño, Javier, Ciruela, Francisco
Published in Journal of medicinal chemistry (09.01.2014)
Published in Journal of medicinal chemistry (09.01.2014)
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Journal Article
Temperature-specific competition in predatory mites: Implications for biological pest control in a changing climate
Guzmán, Celeste, Aguilar-Fenollosa, Ernestina, Sahún, Rosa M., Boyero, Juan Ramón, Vela, José Miguel, Wong, Eva, Jaques, Josep Anton, Montserrat, Marta
Published in Agriculture, ecosystems & environment (15.01.2016)
Published in Agriculture, ecosystems & environment (15.01.2016)
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Journal Article