Multisite phosphorylation is required for sustained interaction with GRKs and arrestins during rapid μ-opioid receptor desensitization
Miess, Elke, Gondin, Arisbel B, Yousuf, Arsalan, Steinborn, Ralph, Mösslein, Nadja, Yang, Yunshi, Göldner, Martin, Ruland, Julia G, Bünemann, Moritz, Krasel, Cornelius, Christie, MacDonald J, Halls, Michelle L, Schulz, Stefan, Canals, Meritxell
Published in Science signaling (17.07.2018)
Published in Science signaling (17.07.2018)
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Journal Article
ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not β-Arrestin
Saaber, Friederike, Schütz, Dagmar, Miess, Elke, Abe, Philipp, Desikan, Srinidhi, Ashok Kumar, Praveen, Balk, Sara, Huang, Ke, Beaulieu, Jean Martin, Schulz, Stefan, Stumm, Ralf
Published in Cell reports (Cambridge) (05.02.2019)
Published in Cell reports (Cambridge) (05.02.2019)
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Journal Article
Differentiation of opioid drug effects by hierarchical multi-site phosphorylation
Just, Sascha, Illing, Susann, Trester-Zedlitz, Michelle, Lau, Elaine K, Kotowski, Sarah J, Miess, Elke, Mann, Anika, Doll, Christian, Trinidad, Jonathan C, Burlingame, Alma L, von Zastrow, Mark, Schulz, Stefan
Published in Molecular pharmacology (01.03.2013)
Published in Molecular pharmacology (01.03.2013)
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Journal Article
Reply to: How carvedilol does not activate β2-adrenoceptors
Kostenis, Evi, Gomeza, Jesus, Miess-Tanneberg, Elke, Blum, Nina Kathleen, Benkel, Tobias, Chevigné, Andy, Hoffmann, Carsten, Kolb, Peter, Nikolaev, Viacheslav, Waldhoer, Maria, Szpakowska, Martyna, Inoue, Asuka, Schulz, Stefan
Published in Nature communications (30.11.2023)
Published in Nature communications (30.11.2023)
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Journal Article
How Carvedilol activates β2-adrenoceptors
Benkel, Tobias, Zimmermann, Mirjam, Zeiner, Julian, Bravo, Sergi, Merten, Nicole, Lim, Victor Jun Yu, Matthees, Edda Sofie Fabienne, Drube, Julia, Miess-Tanneberg, Elke, Malan, Daniela, Szpakowska, Martyna, Monteleone, Stefania, Grimes, Jak, Koszegi, Zsombor, Lanoiselée, Yann, O’Brien, Shannon, Pavlaki, Nikoleta, Dobberstein, Nadine, Inoue, Asuka, Nikolaev, Viacheslav, Calebiro, Davide, Chevigné, Andy, Sasse, Philipp, Schulz, Stefan, Hoffmann, Carsten, Kolb, Peter, Waldhoer, Maria, Simon, Katharina, Gomeza, Jesus, Kostenis, Evi
Published in Nature communications (19.11.2022)
Published in Nature communications (19.11.2022)
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Journal Article
The CENP-T C-terminus is exclusively proximal to H3.1 and not to H3.2 or H3.3
Abendroth, Christian, Hofmeister, Antje, Hake, Sandra B, Kamweru, Paul K, Miess, Elke, Dornblut, Carsten, Küffner, Isabell, Deng, Wen, Leonhardt, Heinrich, Orthaus, Sandra, Hoischen, Christian, Diekmann, Stephan
Published in International journal of molecular sciences (12.03.2015)
Published in International journal of molecular sciences (12.03.2015)
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Journal Article
A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening
Kaufmann, Johanna, Blum, Nina Kathleen, Nagel, Falko, Schuler, Anna, Drube, Julia, Degenhart, Carsten, Engel, Julian, Eickhoff, Jan Eicke, Dasgupta, Pooja, Fritzwanker, Sebastian, Guastadisegni, Maria, Schulte, Clemens, Miess-Tanneberg, Elke, Maric, Hans Michael, Spetea, Mariana, Kliewer, Andrea, Baumann, Matthias, Klebl, Bert, Reinscheid, Rainer K., Hoffmann, Carsten, Schulz, Stefan
Published in Communications biology (09.11.2022)
Published in Communications biology (09.11.2022)
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Journal Article
Targeting multiple opioid receptors – improved analgesics with reduced side effects?
Günther, Thomas, Dasgupta, Pooja, Mann, Anika, Miess, Elke, Kliewer, Andrea, Fritzwanker, Sebastian, Steinborn, Ralph, Schulz, Stefan
Published in British journal of pharmacology (01.07.2018)
Published in British journal of pharmacology (01.07.2018)
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Journal Article
Different mechanisms of homologous and heterologous μ‐opioid receptor phosphorylation
Mann, Anika, Illing, Susann, Miess, Elke, Schulz, Stefan
Published in British journal of pharmacology (01.01.2015)
Published in British journal of pharmacology (01.01.2015)
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Journal Article
Role of Phosphorylation Sites in Desensitization of µ-Opioid Receptor
Yousuf, Arsalan, Miess, Elke, Sianati, Setareh, Du, Yan-Ping, Schulz, Stefan, Christie, MacDonald J
Published in Molecular pharmacology (01.10.2015)
Published in Molecular pharmacology (01.10.2015)
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Journal Article
Discovery of a Biased Allosteric Modulator for Cannabinoid 1 Receptor: Preclinical Anti-Glaucoma Efficacy
Garai, Sumanta, Leo, Luciana M, Szczesniak, Anna-Maria, Hurst, Dow P, Schaffer, Peter C, Zagzoog, Ayat, Black, Tallan, Deschamps, Jeffrey R, Miess, Elke, Schulz, Stefan, Janero, David R, Straiker, Alex, Pertwee, Roger G, Abood, Mary E, Kelly, Melanie E. M, Reggio, Patricia H, Laprairie, Robert B, Thakur, Ganesh A
Published in Journal of medicinal chemistry (24.06.2021)
Published in Journal of medicinal chemistry (24.06.2021)
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Journal Article
The NPXXY Motif Regulates β-Arrestin Recruitment by the CB1 Cannabinoid Receptor
Leo, Luciana M, Al-Zoubi, Rufaida, Hurst, Dow P, Stephan, Anna P, Zhao, Pingwei, Tilley, Douglas G, Miess, Elke, Schulz, Stefan, Abood, Mary E, Reggio, Patricia H
Published in Cannabis and cannabinoid research (01.10.2023)
Published in Cannabis and cannabinoid research (01.10.2023)
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Journal Article
How Carvedilol activates β 2 -adrenoceptors
Benkel, Tobias, Zimmermann, Mirjam, Zeiner, Julian, Bravo, Sergi, Merten, Nicole, Lim, Victor Jun Yu, Matthees, Edda Sofie Fabienne, Drube, Julia, Miess-Tanneberg, Elke, Malan, Daniela, Szpakowska, Martyna, Monteleone, Stefania, Grimes, Jak, Koszegi, Zsombor, Lanoiselée, Yann, O'Brien, Shannon, Pavlaki, Nikoleta, Dobberstein, Nadine, Inoue, Asuka, Nikolaev, Viacheslav, Calebiro, Davide, Chevigné, Andy, Sasse, Philipp, Schulz, Stefan, Hoffmann, Carsten, Kolb, Peter, Waldhoer, Maria, Simon, Katharina, Gomeza, Jesus, Kostenis, Evi
Published in Nature communications (19.11.2022)
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Published in Nature communications (19.11.2022)
Journal Article
A bead-based GPCR phosphorylation immunoassay for high-throughput ligand profiling and GRK inhibitor screening
Kaufmann, Johanna, Blum, Nina Kathleen, Nagel, Falko, Anna Schuler Anna Schuler, Drube, Julia, Degenhart, Carsten, Engel, Julian, Jan Eicke Eickhoff, Dasgupta, Pooja, Fritzwanker, Sebastian, Guastadisegni, Maria, Schulte, Clemens, Miess-Tanneberg, Elke, Maric, Hans Michael, Spetea, Mariana, Kliewer, Andrea, Baumann, Matthias, Klebl, Bert, Reinscheid, Rainer K, Hoffmann, Carsten, Schulz, Stefan
Published in bioRxiv (25.07.2022)
Published in bioRxiv (25.07.2022)
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