The crowding dynamics of the motor protein kinesin-II
Kushwaha, Vandana S, Acar, Seyda, Miedema, Daniël M, Denisov, Dmitry V, Schall, Peter, Peterman, Erwin J G
Published in PloS one (13.02.2020)
Published in PloS one (13.02.2020)
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Marker-free lineage tracing reveals an environment-instructed clonogenic hierarchy in pancreatic cancer
Lodestijn, Sophie C., Miedema, Daniël M., Lenos, Kristiaan J., Nijman, Lisanne E., Belt, Saskia C., El Makrini, Khalid, Lecca, Maria C., Waasdorp, Cynthia, van den Bosch, Tom, Bijlsma, Maarten F., Vermeulen, Louis
Published in Cell reports (Cambridge) (19.10.2021)
Published in Cell reports (Cambridge) (19.10.2021)
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Karyotype evolution in response to chemoradiotherapy and upon recurrence of esophageal adenocarcinomas
van der Sluis, Karen, van Sandick, Johanna W., Koemans, Willem J., van den Bosch, Tom, Broeks, Annegien, Peters, Dennis, Seignette, Iris M., Rausch, Christian R., van Dijk, Erik, Snaebjornsson, Petur, van den Berg, José G., van Grieken, Nicole C.T., Ylstra, Bauke, Carvalho, Beatriz, Miedema, Daniël M., Kodach, Liudmila L.
Published in Cell reports (Cambridge) (01.11.2024)
Published in Cell reports (Cambridge) (01.11.2024)
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Quantitative models for the inference of intratumor heterogeneity
Bosch, Tom, Vermeulen, Louis, Miedema, Daniël M.
Published in Computational and systems oncology (01.06.2022)
Published in Computational and systems oncology (01.06.2022)
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Cancer stem cells: here, there, and everywhere
Lodestijn, Sophie C., Lenos, Kristiaan J., Miedema, Daniël M., Bijlsma, Maarten F., Vermeulen, Louis
Published in Molecular & cellular oncology (01.01.2019)
Published in Molecular & cellular oncology (01.01.2019)
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Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer
Lenos, Kristiaan J., Miedema, Daniël M., Lodestijn, Sophie C., Nijman, Lisanne E., van den Bosch, Tom, Romero Ros, Xavier, Lourenço, Filipe C., Lecca, Maria C., van der Heijden, Maartje, van Neerven, Sanne M., van Oort, Anita, Leveille, Nicolas, Adam, Ronja S., de Sousa E Melo, Felipe, Otten, Joy, Veerman, Patrick, Hypolite, Guillaume, Koens, Lianne, Lyons, Scott K., Stassi, Giorgio, Winton, Douglas J., Medema, Jan Paul, Morrissey, Edward, Bijlsma, Maarten F., Vermeulen, Louis
Published in Nature cell biology (01.10.2018)
Published in Nature cell biology (01.10.2018)
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Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts
van der Heijden, Maartje, Miedema, Daniël M., Waclaw, Bartlomiej, Veenstra, Veronique L., Lecca, Maria C., Nijman, Lisanne E., van Dijk, Erik, van Neerven, Sanne M., Lodestijn, Sophie C., Lenos, Kristiaan J., de Groot, Nina E., Prasetyanti, Pramudita R., Varea, Andrea Arricibita, Winton, Douglas J., Medema, Jan Paul, Morrissey, Edward, Ylstra, Bauke, Nowak, Martin A., Bijlsma, Maarten F., Vermeulen, Louis
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (26.03.2019)
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Journal Article
Chromosomal copy number heterogeneity predicts survival rates across cancers
van Dijk, Erik, van den Bosch, Tom, Lenos, Kristiaan J., El Makrini, Khalid, Nijman, Lisanne E., van Essen, Hendrik F. B., Lansu, Nico, Boekhout, Michiel, Hageman, Joris H., Fitzgerald, Rebecca C., Punt, Cornelis J. A., Tuynman, Jurriaan B., Snippert, Hugo J. G., Kops, Geert J. P. L., Medema, Jan Paul, Ylstra, Bauke, Vermeulen, Louis, Miedema, Daniël M.
Published in Nature communications (27.05.2021)
Published in Nature communications (27.05.2021)
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Journal Article
Chromosome 20 loss is characteristic of breast implant–associated anaplastic large cell lymphoma
Los-de Vries, G. Tjitske, de Boer, Mintsje, van Dijk, Erik, Stathi, Phylicia, Hijmering, Nathalie J., Roemer, Margaretha G.M., Mendeville, Matias, Miedema, Daniel M., de Boer, Jan Paul, Rakhorst, Hinne A., van Leeuwen, Flora E., van der Hulst, René R.W.J., Ylstra, Bauke, de Jong, Daphne
Published in Blood (17.12.2020)
Published in Blood (17.12.2020)
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Author Correction: The evolution of lung cancer and impact of subclonal selection in TRACERx
Frankell, Alexander M., Dietzen, Michelle, Al Bakir, Maise, Lim, Emilia L., Karasaki, Takahiro, Ward, Sophia, Veeriah, Selvaraju, Colliver, Emma, Huebner, Ariana, Bunkum, Abigail, Hill, Mark S., Grigoriadis, Kristiana, Moore, David A., Black, James R. M., Liu, Wing Kin, Thol, Kerstin, Pich, Oriol, Watkins, Thomas B. K., Naceur-Lombardelli, Cristina, Cook, Daniel E., Salgado, Roberto, Wilson, Gareth A., Bailey, Chris, Angelova, Mihaela, Bentham, Robert, Martínez-Ruiz, Carlos, Abbosh, Christopher, Nicholson, Andrew G., Le Quesne, John, Biswas, Dhruva, Rosenthal, Rachel, Puttick, Clare, Hessey, Sonya, Lee, Claudia, Prymas, Paulina, Toncheva, Antonia, Smith, Jon, Xing, Wei, Nicod, Jerome, Price, Gillian, Kerr, Keith M., Naidu, Babu, Middleton, Gary, Blyth, Kevin G., Fennell, Dean A., Forster, Martin D., Lee, Siow Ming, Falzon, Mary, Hewish, Madeleine, Shackcloth, Michael J., Lim, Eric, Benafif, Sarah, Russell, Peter, Boleti, Ekaterini, Krebs, Matthew G., Lester, Jason F., Papadatos-Pastos, Dionysis, Ahmad, Tanya, Thakrar, Ricky M., Lawrence, David, Navani, Neal, Janes, Sam M., Dive, Caroline, Blackhall, Fiona H., Summers, Yvonne, Cave, Judith, Marafioti, Teresa, Herrero, Javier, Quezada, Sergio A., Peggs, Karl S., Schwarz, Roland F., Van Loo, Peter, Miedema, Daniël M., Birkbak, Nicolai J., Hiley, Crispin T., Hackshaw, Allan, Zaccaria, Simone, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Swanton, Charles
Published in Nature (London) (25.07.2024)
Published in Nature (London) (25.07.2024)
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Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas
Lodestijn, Sophie C., van den Bosch, Tom, Nijman, Lisanne E., Moreno, Leandro F., Schlingemann, Sophie, Sheraton, Vivek M., van Neerven, Sanne M., Koning, Jasper J., Vieira Braga, Felipe A., Paauw, Nanne J., Lecca, Maria C., Lenos, Kristiaan J., Morrissey, Edward, Miedema, Daniël M., Winton, Douglas J., Bijlsma, Maarten F., Vermeulen, Louis
Published in Cell stem cell (04.11.2021)
Published in Cell stem cell (04.11.2021)
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Journal Article
A marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue
Lenos, Kristiaan J., Lodestijn, Sophie C., Lyons, Scott K., Bijlsma, Maarten F., Miedema, Daniël M., Vermeulen, Louis
Published in Nature protocols (01.09.2019)
Published in Nature protocols (01.09.2019)
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Journal Article
Predicting survival of cancer patients by chromosomal copy number heterogeneity
Van Den Bosch, Tom, van Dijk, Erik, Vermeulen, Louis, Miedema, Daniël M.
Published in Molecular & cellular oncology (04.07.2021)
Published in Molecular & cellular oncology (04.07.2021)
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Journal Article
Predictors of 30-Day Mortality Among Dutch Patients Undergoing Colorectal Cancer Surgery, 2011-2016
van den Bosch, Tom, Warps, Anne-Loes K, de Nerée Tot Babberich, Michael P M, Stamm, Christina, Geerts, Bart F, Vermeulen, Louis, Wouters, Michel W J M, Dekker, Jan Willem T, Tollenaar, Rob A E M, Tanis, Pieter J, Miedema, Daniël M
Published in JAMA network open (26.04.2021)
Published in JAMA network open (26.04.2021)
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Journal Article
Chromosome 20 loss is characteristic of breast implant-associated anaplastic large cell lymphoma
Los-de Vries, G Tjitske, de Boer, Mintsje, van Dijk, Erik, Stathi, Phylicia, Hijmering, Nathalie J, Roemer, Margaretha G M, Mendeville, Matias, Miedema, Daniel M, de Boer, Jan Paul, Rakhorst, Hinne A, van Leeuwen, Flora E, van der Hulst, René R W J, Ylstra, Bauke, de Jong, Daphne
Published in Blood (17.12.2020)
Published in Blood (17.12.2020)
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Journal Article
How Kinesin Motor Proteins Deal with Traffic Jams
Kushwaha, Vandana S., Miedema, Daniël M., Denisov, Dmitry V., Acar, Seyda, Nienhuis, Bernard, Schall, Peter, Peterman, Erwin J.G.
Published in Biophysical journal (16.02.2016)
Published in Biophysical journal (16.02.2016)
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