Molecular mechanisms of protein aggregation from global fitting of kinetic models
Meisl, Georg, Kirkegaard, Julius B, Arosio, Paolo, Michaels, Thomas C T, Vendruscolo, Michele, Dobson, Christopher M, Linse, Sara, Knowles, Tuomas P J
Published in Nature protocols (01.02.2016)
Published in Nature protocols (01.02.2016)
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Journal Article
Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation
Michaels, Thomas C.T, Šari, An ela, Habchi, Johnny, Chia, Sean, Meisl, Georg, Vendruscolo, Michele, Dobson, Christopher M, Knowles, Tuomas P.J
Published in Annual review of physical chemistry (20.04.2018)
Published in Annual review of physical chemistry (20.04.2018)
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Journal Article
Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide
Michaels, Thomas C T, Šarić, Andela, Curk, Samo, Bernfur, Katja, Arosio, Paolo, Meisl, Georg, Dear, Alexander J, Cohen, Samuel I A, Dobson, Christopher M, Vendruscolo, Michele, Linse, Sara, Knowles, Tuomas P J
Published in Nature chemistry (01.05.2020)
Published in Nature chemistry (01.05.2020)
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Journal Article
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
Galvagnion, Céline, Buell, Alexander K, Meisl, Georg, Michaels, Thomas C T, Vendruscolo, Michele, Knowles, Tuomas P J, Dobson, Christopher M
Published in Nature chemical biology (01.03.2015)
Published in Nature chemical biology (01.03.2015)
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Journal Article
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
Habchi, Johnny, Chia, Sean, Galvagnion, Céline, Michaels, Thomas C T, Bellaiche, Mathias M J, Ruggeri, Francesco Simone, Sanguanini, Michele, Idini, Ilaria, Kumita, Janet R, Sparr, Emma, Linse, Sara, Dobson, Christopher M, Knowles, Tuomas P J, Vendruscolo, Michele
Published in Nature chemistry (01.06.2018)
Published in Nature chemistry (01.06.2018)
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Journal Article
Scaling analysis reveals the mechanism and rates of prion replication in vivo
Meisl, Georg, Kurt, Timothy, Condado-Morales, Itzel, Bett, Cyrus, Sorce, Silvia, Nuvolone, Mario, Michaels, Thomas C T, Heinzer, Daniel, Avar, Merve, Cohen, Samuel I A, Hornemann, Simone, Aguzzi, Adriano, Dobson, Christopher M, Sigurdson, Christina J, Knowles, Tuomas P J
Published in Nature structural & molecular biology (01.04.2021)
Published in Nature structural & molecular biology (01.04.2021)
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Journal Article
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils
Song, Yang, Michaels, Thomas C T, Ma, Qingming, Liu, Zhou, Yuan, Hao, Takayama, Shuichi, Knowles, Tuomas P J, Shum, Ho Cheung
Published in Nature communications (29.05.2018)
Published in Nature communications (29.05.2018)
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Journal Article
A solid beta-sheet structure is formed at the surface of FUS droplets during aging
Emmanouilidis, Leonidas, Bartalucci, Ettore, Kan, Yelena, Ijavi, Mahdiye, Pérez, Maria Escura, Afanasyev, Pavel, Boehringer, Daniel, Zehnder, Johannes, Parekh, Sapun H, Bonn, Mischa, Michaels, Thomas C T, Wiegand, Thomas, Allain, Frédéric H-T
Published in Nature chemical biology (01.08.2024)
Published in Nature chemical biology (01.08.2024)
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Journal Article
Physical determinants of the self-replication of protein fibrils
Šarić, Anđela, Buell, Alexander K, Meisl, Georg, Michaels, Thomas C T, Dobson, Christopher M, Linse, Sara, Knowles, Tuomas P J, Frenkel, Daan
Published in Nature physics (01.09.2016)
Published in Nature physics (01.09.2016)
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Journal Article
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
Arosio, Paolo, Michaels, Thomas C T, Linse, Sara, Månsson, Cecilia, Emanuelsson, Cecilia, Presto, Jenny, Johansson, Jan, Vendruscolo, Michele, Dobson, Christopher M, Knowles, Tuomas P J
Published in Nature communications (24.03.2016)
Published in Nature communications (24.03.2016)
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Journal Article
Analytical Solution to the Flory–Huggins Model
Qian, Daoyuan, Michaels, Thomas C. T., Knowles, Tuomas P. J.
Published in The journal of physical chemistry letters (25.08.2022)
Published in The journal of physical chemistry letters (25.08.2022)
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Journal Article
The catalytic nature of protein aggregation
Dear, Alexander J, Meisl, Georg, Michaels, Thomas C T, Zimmermann, Manuela R, Linse, Sara, Knowles, Tuomas P J
Published in The Journal of chemical physics (31.01.2020)
Published in The Journal of chemical physics (31.01.2020)
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Journal Article
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly
Adler-Abramovich, Lihi, Marco, Pini, Arnon, Zohar A, Creasey, Rhiannon C. G, Michaels, Thomas C. T, Levin, Aviad, Scurr, David J, Roberts, Clive J, Knowles, Tuomas P. J, Tendler, Saul J. B, Gazit, Ehud
Published in ACS nano (23.08.2016)
Published in ACS nano (23.08.2016)
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Journal Article
Direct Observation of Oligomerization by Single Molecule Fluorescence Reveals a Multistep Aggregation Mechanism for the Yeast Prion Protein Ure2
Yang, Jie, Dear, Alexander J, Michaels, Thomas C. T, Dobson, Christopher M, Knowles, Tuomas P. J, Wu, Si, Perrett, Sarah
Published in Journal of the American Chemical Society (21.02.2018)
Published in Journal of the American Chemical Society (21.02.2018)
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Journal Article
Dynamic microfluidic control of supramolecular peptide self-assembly
Arnon, Zohar A, Vitalis, Andreas, Levin, Aviad, Michaels, Thomas C T, Caflisch, Amedeo, Knowles, Tuomas P J, Adler-Abramovich, Lihi, Gazit, Ehud
Published in Nature communications (25.10.2016)
Published in Nature communications (25.10.2016)
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Journal Article
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
Dada, Samuel T, Hardenberg, Maarten C, Toprakcioglu, Zenon, Mrugalla, Lena K, Cali, Mariana P, McKeon, Mollie O, Klimont, Ewa, Michaels, Thomas C T, Knowles, Tuomas P J, Vendruscolo, Michele
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (28.02.2023)
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