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Structural elements in the flexible tail of the co-chaperone p23 coordinate client binding and progression of the Hsp90 chaperone cycle
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Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1
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Noncanonical inhibition of caspase-3 by a nuclear microRNA confers endothelial protection by autophagy in atherosclerosis
Santovito, Donato, Egea, Virginia, Bidzhekov, Kiril, Natarelli, Lucia, Mourão, André, Blanchet, Xavier, Wichapong, Kanin, Aslani, Maria, Brunßen, Coy, Horckmans, Michael, Hristov, Michael, Geerlof, Arie, Lutgens, Esther, Daemen, Mat J A P, Hackeng, Tilman, Ries, Christian, Chavakis, Triantafyllos, Morawietz, Henning, Naumann, Ronald, von Hundelshausen, Philipp, Steffens, Sabine, Duchêne, Johan, Megens, Remco T A, Sattler, Michael, Weber, Christian
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Recent advances in half-life extension strategies for therapeutic peptides and proteins
Tan, Huanbo, Su, Wencheng, Zhang, Wenyu, Wang, Pengju, Sattler, Michael, Zou, Peijian
Published in Current pharmaceutical design (01.01.2018)
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Conformational dynamics modulate the catalytic activity of the molecular chaperone Hsp90
Mader, Sophie L, Lopez, Abraham, Lawatscheck, Jannis, Luo, Qi, Rutz, Daniel A, Gamiz-Hernandez, Ana P, Sattler, Michael, Buchner, Johannes, Kaila, Ville R I
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Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins
Tripsianes, Konstantinos, Madl, Tobias, Machyna, Martin, Fessas, Dimitrios, Englbrecht, Clemens, Fischer, Utz, Neugebauer, Karla M, Sattler, Michael
Published in Nature structural & molecular biology (01.12.2011)
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Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
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Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
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Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein
Lorenz, Oliver Robin, Freiburger, Lee, Rutz, Daniel Andreas, Krause, Maike, Zierer, Bettina Karolina, Alvira, Sara, Cuéllar, Jorge, Valpuesta, José María, Madl, Tobias, Sattler, Michael, Buchner, Johannes
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Published in Molecular cell (20.03.2014)
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The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range
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The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs
Lingaraju, Mahesh, Johnsen, Dennis, Schlundt, Andreas, Langer, Lukas M, Basquin, Jérôme, Sattler, Michael, Heick Jensen, Torben, Falk, Sebastian, Conti, Elena
Published in Nature communications (29.07.2019)
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Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
Schneider, Tim, Hung, Lee-Hsueh, Aziz, Masood, Wilmen, Anna, Thaum, Stephanie, Wagner, Jacqueline, Janowski, Robert, Müller, Simon, Schreiner, Silke, Friedhoff, Peter, Hüttelmaier, Stefan, Niessing, Dierk, Sattler, Michael, Schlundt, Andreas, Bindereif, Albrecht
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Structural basis for specific RNA recognition by the alternative splicing factor RBM5
Soni, Komal, Jagtap, Pravin Kumar Ankush, Martínez-Lumbreras, Santiago, Bonnal, Sophie, Geerlof, Arie, Stehle, Ralf, Simon, Bernd, Valcárcel, Juan, Sattler, Michael
Published in Nature communications (15.07.2023)
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Importance of cycle timing for the function of the molecular chaperone Hsp90
Zierer, Bettina K, Rübbelke, Martin, Tippel, Franziska, Madl, Tobias, Schopf, Florian H, Rutz, Daniel A, Richter, Klaus, Sattler, Michael, Buchner, Johannes
Published in Nature structural & molecular biology (01.11.2016)
Published in Nature structural & molecular biology (01.11.2016)
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Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation
Schlundt, Andreas, Heinz, Gitta A, Janowski, Robert, Geerlof, Arie, Stehle, Ralf, Heissmeyer, Vigo, Niessing, Dierk, Sattler, Michael
Published in Nature structural & molecular biology (01.08.2014)
Published in Nature structural & molecular biology (01.08.2014)
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Multi―domain conformational selection underlies pre―mRNA splicing regulation by U2AF
MACKERETH, Cameron D, MADL, Tobias, BONNAL, Sophie, SIMON, Bernd, ZANIER, Katia, GASCH, Alexander, RYBIN, Vladimir, VALCARCEL, Juan, SATTLER, Michael
Published in Nature (London) (21.07.2011)
Published in Nature (London) (21.07.2011)
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