Long-term results of the fludarabine, cyclophosphamide, and rituximab regimen as initial therapy of chronic lymphocytic leukemia
Tam, Constantine S., O'Brien, Susan, Wierda, William, Kantarjian, Hagop, Wen, Sijin, Do, Kim-Anh, Thomas, Deborah A., Cortes, Jorge, Lerner, Susan, Keating, Michael J.
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CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
Savoldo, Barbara, Ramos, Carlos Almeida, Liu, Enli, Mims, Martha P, Keating, Michael J, Carrum, George, Kamble, Rammurti T, Bollard, Catherine M, Gee, Adrian P, Mei, Zhuyong, Liu, Hao, Grilley, Bambi, Rooney, Cliona M, Heslop, Helen E, Brenner, Malcolm K, Dotti, Gianpietro
Published in The Journal of clinical investigation (01.05.2011)
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Complex karyotype is a stronger predictor than del(17p) for an inferior outcome in relapsed or refractory chronic lymphocytic leukemia patients treated with ibrutinib‐based regimens
Thompson, Philip A., O'Brien, Susan M., Wierda, William G., Ferrajoli, Alessandra, Stingo, Francesco, Smith, Susan C., Burger, Jan A., Estrov, Zeev, Jain, Nitin, Kantarjian, Hagop M., Keating, Michael J.
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Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis
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Published in The Journal of biological chemistry (16.09.2011)
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Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia
Zhang, Wan, Trachootham, Dunyaporn, Liu, Jinyun, Chen, Gang, Pelicano, Helene, Garcia-Prieto, Celia, Lu, Weiqin, Burger, Jan A., Croce, Carlo M., Plunkett, William, Keating, Michael J., Huang, Peng
Published in Nature cell biology (01.03.2012)
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The Spiegelmer NOX-A12, a novel CXCL12 inhibitor, interferes with chronic lymphocytic leukemia cell motility and causes chemosensitization
Hoellenriegel, Julia, Zboralski, Dirk, Maasch, Christian, Rosin, Nathalie Y., Wierda, William G., Keating, Michael J., Kruschinski, Anna, Burger, Jan A.
Published in Blood (13.02.2014)
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Eradication of bone marrow minimal residual disease may prompt early treatment discontinuation in CLL
Strati, Paolo, Keating, Michael J., O’Brien, Susan M., Burger, Jan, Ferrajoli, Alessandra, Jain, Nitin, Tambaro, Francesco Paolo, Estrov, Zeev, Jorgensen, Jeffrey, Challagundla, Pramoda, Faderl, Stefan H., Wierda, William G.
Published in Blood (12.06.2014)
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A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia
Chen, Lisa S., Bose, Prithviraj, Cruz, Nichole D., Jiang, Yongying, Wu, Qi, Thompson, Philip A., Feng, Shuju, Kroll, Michael H., Qiao, Wei, Huang, Xuelin, Jain, Nitin, Wierda, William G., Keating, Michael J., Gandhi, Varsha
Published in Blood (22.11.2018)
Published in Blood (22.11.2018)
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Long-term Follow-up of Treatment with Ibrutinib and Rituximab in Patients with High-Risk Chronic Lymphocytic Leukemia
Jain, Preetesh, Keating, Michael J, Wierda, William G, Sivina, Mariela, Thompson, Philip A, Ferrajoli, Alessandra, Estrov, Zeev, Kantarjian, Hagop, O'Brien, Susan, Burger, Jan A
Published in Clinical cancer research (01.05.2017)
Published in Clinical cancer research (01.05.2017)
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Minimal residual disease undetectable by next-generation sequencing predicts improved outcome in CLL after chemoimmunotherapy
Thompson, Philip A., Srivastava, Jaya, Peterson, Christine, Strati, Paolo, Jorgensen, Jeffrey L., Hether, Tyler, Keating, Michael J., O'Brien, Susan M., Ferrajoli, Alessandra, Burger, Jan A., Estrov, Zeev, Jain, Nitin, Wierda, William G.
Published in Blood (28.11.2019)
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The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells
Fiorcari, Stefania, Brown, Wells S, McIntyre, Bradley W, Estrov, Zeev, Maffei, Rossana, O'Brien, Susan, Sivina, Mariela, Hoellenriegel, Julia, Wierda, William G, Keating, Michael J, Ding, Wei, Kay, Neil E, Lannutti, Brian J, Marasca, Roberto, Burger, Jan A
Published in PloS one (23.12.2013)
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K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis
Hu, Yumin, Lu, Weiqin, Chen, Gang, Wang, Peng, Chen, Zhao, Zhou, Yan, Ogasawara, Marcia, Trachootham, Dunyaporn, Feng, Li, Pelicano, Helene, Chiao, Paul J, Keating, Michael J, Garcia-Manero, Guillermo, Huang, Peng
Published in Cell research (01.02.2012)
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Cyclin-dependent kinase inhibitor fadraciclib (CYC065) depletes anti-apoptotic protein and synergizes with venetoclax in primary chronic lymphocytic leukemia cells
Chen, Rong, Chen, Yuling, Xiong, Ping, Zheleva, Daniella, Blake, David, Keating, Michael J., Wierda, William G., Plunkett, William
Published in Leukemia (01.06.2022)
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Management of adverse events associated with idelalisib treatment: expert panel opinion
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Published in Leukemia & lymphoma (03.10.2015)
Published in Leukemia & lymphoma (03.10.2015)
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Phase II Study of Lenalidomide and Rituximab As Salvage Therapy for Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia
BADOUX, Xavier C, KEATING, Michael J, SIJIN WEN, WIERDA, William G, O'BRIEN, Susan M, PADERL, Stefan, SARGENT, Rachel, BURGER, Jan A, FERRAJOLI, Alessandra
Published in Journal of clinical oncology (10.02.2013)
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Chemoimmunotherapy With a Modified Hyper-CVAD and Rituximab Regimen Improves Outcome in De Novo Philadelphia Chromosome–Negative Precursor B-Lineage Acute Lymphoblastic Leukemia
THOMAS, Deborah A, O'BRIEN, Susan, ANDREEFF, Michael, PIERCE, Sherry, GARRIS, Rebecca, KEATING, Michael J, CORTES, Jorge, KANTARJIAN, Hagop M, FADERL, Stefan, GARCIA-MANERO, Guillermo, FERRAJOLI, Alessandra, WIERDA, William, RAVANDI, Farhad, VERSTOVSEK, Srdan, JORGENSEN, Jeffrey L, BUESO-RAMOS, Carlos
Published in Journal of clinical oncology (20.08.2010)
Published in Journal of clinical oncology (20.08.2010)
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Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia
Yin, Qingsong, Sivina, Mariela, Robins, Harlan, Yusko, Erik, Vignali, Marissa, O'Brien, Susan, Keating, Michael J, Ferrajoli, Alessandra, Estrov, Zeev, Jain, Nitin, Wierda, William G, Burger, Jan A
Published in The Journal of immunology (1950) (15.02.2017)
Published in The Journal of immunology (1950) (15.02.2017)
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