HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy
McManus, William R, Bale, Michael J, Spindler, Jonathan, Wiegand, Ann, Musick, Andrew, Patro, Sean C, Sobolewski, Michele D, Musick, Victoria K, Anderson, Elizabeth M, Cyktor, Joshua C, Halvas, Elias K, Shao, Wei, Wells, Daria, Wu, Xiaolin, Keele, Brandon F, Milush, Jeffrey M, Hoh, Rebecca, Mellors, John W, Hughes, Stephen H, Deeks, Steven G, Coffin, John M, Kearney, Mary F
Published in The Journal of clinical investigation (01.11.2019)
Published in The Journal of clinical investigation (01.11.2019)
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Mechanisms of epigenomic and functional convergence between glucocorticoid- and IL4-driven macrophage programming
Deochand, Dinesh K., Dacic, Marija, Bale, Michael J., Daman, Andrew W., Chaudhary, Vidyanath, Josefowicz, Steven Z., Oliver, David, Chinenov, Yurii, Rogatsky, Inez
Published in Nature communications (18.10.2024)
Published in Nature communications (18.10.2024)
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An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses
Wells, Daria W, Guo, Shuang, Shao, Wei, Bale, Michael J, Coffin, John M, Hughes, Stephen H, Wu, Xiaolin
Published in BMC genomics (09.03.2020)
Published in BMC genomics (09.03.2020)
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Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays
Kuzmichev, Yury V., Lackman-Smith, Carol, Bakkour, Sonia, Wiegand, Ann, Bale, Michael J., Musick, Andrew, Bernstein, Wendy, Aronson, Naomi, Ake, Julie, Tovanabutra, Sodsai, Stone, Mars, Ptak, Roger G., Kearney, Mary F., Busch, Michael P., Wonderlich, Elizabeth R., Kulpa, Deanna A.
Published in Scientific reports (06.07.2023)
Published in Scientific reports (06.07.2023)
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Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy
Coffin, John M, Bale, Michael J, Wells, Daria, Guo, Shuang, Luke, Brian, Zerbato, Jennifer M, Sobolewski, Michele D, Sia, Twan, Shao, Wei, Wu, Xiaolin, Maldarelli, Frank, Kearney, Mary F, Mellors, John W, Hughes, Stephen H
Published in PLoS pathogens (01.04.2021)
Published in PLoS pathogens (01.04.2021)
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Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
Wonderlich, Elizabeth R, Subramanian, Krupa, Cox, Bryan, Wiegand, Ann, Lackman-Smith, Carol, Bale, Michael J, Stone, Mars, Hoh, Rebecca, Kearney, Mary F, Maldarelli, Frank, Deeks, Steven G, Busch, Michael P, Ptak, Roger G, Kulpa, Deanna A
Published in PLoS pathogens (14.10.2019)
Published in PLoS pathogens (14.10.2019)
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HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus
Musick, Andrew, Spindler, Jonathan, Boritz, Eli, Pérez, Liliana, Crespo-Vélez, Daniel, Patro, Sean C, Sobolewski, Michele D, Bale, Michael J, Reid, Carolyn, Keele, Brandon F, Capoferri, Adam, Shao, Wei, Wiegand, Ann, Simonetti, Francesco R, Mellors, John W, Hughes, Stephen H, Coffin, John M, Maldarelli, Frank, Kearney, Mary F
Published in Frontiers in microbiology (01.10.2019)
Published in Frontiers in microbiology (01.10.2019)
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The largest HIV-1-infected T cell clones in children on long-term combination antiretroviral therapy contain solo LTRs
Botha, Johannes C, Demirov, Dimiter, Gordijn, Carli, Katusiime, Mary Grace, Bale, Michael J, Wu, Xiaolin, Wells, Daria, Hughes, Stephen H, Cotton, Mark F, Mellors, John W, Kearney, Mary F, van Zyl, Gert U
Published in mBio (31.08.2023)
Published in mBio (31.08.2023)
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HIVIntact: a python-based tool for HIV-1 genome intactness inference
Wright, Imogen A, Bale, Michael J, Shao, Wei, Hu, Wei-Shau, Coffin, John M, Van Zyl, Gert U, Kearney, Mary F
Published in Retrovirology (27.06.2021)
Published in Retrovirology (27.06.2021)
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Early Emergence and Long-Term Persistence of HIV-Infected T-Cell Clones in Children
Bale, Michael J, Katusiime, Mary Grace, Wells, Daria, Wu, Xiaolin, Spindler, Jonathan, Halvas, Elias K, Cyktor, Joshua C, Wiegand, Ann, Shao, Wei, Cotton, Mark F, Hughes, Stephen H, Mellors, John W, Coffin, John M, Van Zyl, Gert U, Kearney, Mary F
Published in mBio (08.04.2021)
Published in mBio (08.04.2021)
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Journal Article
CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART
Boltz, Valerie F., Ceriani, Cristina, Rausch, Jason W., Shao, Wei, Bale, Michael J., Keele, Brandon F., Hoh, Rebecca, Milush, Jeffrey M., Deeks, Steve G., Maldarelli, Frank, Kearney, Mary F., Coffin, John M.
Published in Viruses (01.05.2021)
Published in Viruses (01.05.2021)
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HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus
Halvas, Elias K, Joseph, Kevin W, Brandt, Leah D, Guo, Shuang, Sobolewski, Michele D, Jacobs, Jana L, Tumiotto, Camille, Bui, John K, Cyktor, Joshua C, Keele, Brandon F, Morse, Gene D, Bale, Michael J, Shao, Wei, Kearney, Mary F, Coffin, John M, Rausch, Jason W, Wu, Xiaolin, Hughes, Stephen H, Mellors, John W
Published in The Journal of clinical investigation (01.11.2020)
Published in The Journal of clinical investigation (01.11.2020)
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Journal Article
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors
Cheong, Jin-Gyu, Ravishankar, Arjun, Sharma, Siddhartha, Parkhurst, Christopher N., Grassmann, Simon A., Wingert, Claire K., Laurent, Paoline, Ma, Sai, Paddock, Lucinda, Miranda, Isabella C., Karakaslar, Emin Onur, Nehar-Belaid, Djamel, Thibodeau, Asa, Bale, Michael J., Kartha, Vinay K., Yee, Jim K., Mays, Minh Y., Jiang, Chenyang, Daman, Andrew W., Martinez de Paz, Alexia, Ahimovic, Dughan, Ramos, Victor, Lercher, Alexander, Nielsen, Erik, Alvarez-Mulett, Sergio, Zheng, Ling, Earl, Andrew, Yallowitz, Alisha, Robbins, Lexi, LaFond, Elyse, Weidman, Karissa L., Racine-Brzostek, Sabrina, Yang, He S., Price, David R., Leyre, Louise, Rendeiro, André F., Ravichandran, Hiranmayi, Kim, Junbum, Borczuk, Alain C., Rice, Charles M., Jones, R. Brad, Schenck, Edward J., Kaner, Robert J., Chadburn, Amy, Zhao, Zhen, Pascual, Virginia, Elemento, Olivier, Schwartz, Robert E., Buenrostro, Jason D., Niec, Rachel E., Barrat, Franck J., Lief, Lindsay, Sun, Joseph C., Ucar, Duygu, Josefowicz, Steven Z.
Published in Cell (31.08.2023)
Published in Cell (31.08.2023)
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Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection ameliorates secondary influenza A virus disease
Lercher, Alexander, Cheong, Jin-Gyu, Bale, Michael J, Jiang, Chenyang, Hoffmann, Hans-Heinrich, Ashbrook, Alison W, Lewy, Tyler, Yin, Yue S, Quirk, Corrine, DeGrace, Emma J, Chiriboga, Luis, Rosenberg, Brad R, Josefowicz, Steven Z, Rice, Charles M
Published in Immunity (Cambridge, Mass.) (27.09.2024)
Published in Immunity (Cambridge, Mass.) (27.09.2024)
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Journal Article
No evidence of HIV replication in children on antiretroviral therapy
Van Zyl, Gert U, Katusiime, Mary Grace, Wiegand, Ann, McManus, William R, Bale, Michael J, Halvas, Elias K, Luke, Brian, Boltz, Valerie F, Spindler, Jonathan, Laughton, Barbara, Engelbrecht, Susan, Coffin, John M, Cotton, Mark F, Shao, Wei, Mellors, John W, Kearney, Mary F
Published in The Journal of clinical investigation (01.10.2017)
Published in The Journal of clinical investigation (01.10.2017)
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Journal Article
Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors
Patro, Sean C., Brandt, Leah D., Bale, Michael J., Halvas, Elias K., Joseph, Kevin W., Shao, Wei, Wu, Xiaolin, Guo, Shuang, Murrell, Ben, Wiegand, Ann, Spindler, Jonathan, Raley, Castle, Hautman, Christopher, Sobolewski, Michele, Fennessey, Christine M., Hu, Wei-Shau, Luke, Brian, Hasson, Jenna M., Niyongabo, Aurelie, Capoferri, Adam A., Keele, Brandon F., Milush, Jeff, Hoh, Rebecca, Deeks, Steven G., Maldarelli, Frank, Hughes, Stephen H., Coffin, John M., Rausch, Jason W., Mellors, John W., Kearney, Mary F.
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (17.12.2019)
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Intact HIV Proviruses Persist in Children Seven to Nine Years after Initiation of Antiretroviral Therapy in the First Year of Life
Katusiime, Mary Grace, Halvas, Elias K, Wright, Imogen, Joseph, Kevin, Bale, Michael J, Kirby-McCullough, Bronwyn, Engelbrecht, Susan, Shao, Wei, Hu, Wei-Shau, Cotton, Mark F, Mellors, John W, Kearney, Mary F, van Zyl, Gert U
Published in Journal of virology (31.01.2020)
Published in Journal of virology (31.01.2020)
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