Neuronal activity modulates alpha-synuclein aggregation and spreading in organotypic brain slice cultures and in vivo
Wu, Qihui, Shaikh, Muhammad A., Meymand, Emily S., Zhang, Bin, Luk, Kelvin C., Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Acta neuropathologica (01.12.2020)
Published in Acta neuropathologica (01.12.2020)
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α-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate Lewy body diseases in mice
Uemura, Norihito, Marotta, Nicholas P., Ara, Jahan, Meymand, Emily S., Zhang, Bin, Kameda, Hiroshi, Koike, Masato, Luk, Kelvin C., Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Nature communications (28.10.2023)
Published in Nature communications (28.10.2023)
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Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro
Marotta, Nicholas P, Ara, Jahan, Uemura, Norihito, Lougee, Marshall G, Meymand, Emily S, Zhang, Bin, Petersson, E James, Trojanowski, John Q, Lee, Virginia M-Y
Published in Acta neuropathologica communications (24.11.2021)
Published in Acta neuropathologica communications (24.11.2021)
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Conformation-selective tau monoclonal antibodies inhibit tau pathology in primary neurons and a mouse model of Alzheimer's disease
Gibbons, Garrett S, Kim, Soo-Jung, Wu, Qihui, Riddle, Dawn M, Leight, Susan N, Changolkar, Lakshmi, Xu, Hong, Meymand, Emily S, O'Reilly, Mia, Zhang, Bin, Brunden, Kurt R, Trojanowski, John Q, Lee, Virginia M Y
Published in Molecular neurodegeneration (04.11.2020)
Published in Molecular neurodegeneration (04.11.2020)
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LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology progression
Lubben, Noah, Brynildsen, Julia K, Webb, Connor M, Li, Howard L, Leyns, Cheryl E G, Changolkar, Lakshmi, Zhang, Bin, Meymand, Emily S, O'Reilly, Mia, Madaj, Zach, DeWeerd, Daniella, Fell, Matthew J, Lee, Virginia M Y, Bassett, Dani S, Henderson, Michael X
Published in Translational neurodegeneration (04.03.2024)
Published in Translational neurodegeneration (04.03.2024)
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Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
Bassil, Fares, Brown, Hannah J., Pattabhiraman, Shankar, Iwasyk, Joe E., Maghames, Chantal M., Meymand, Emily S., Cox, Timothy O., Riddle, Dawn M., Zhang, Bin, Trojanowski, John Q., Lee, Virginia M.-Y.
Published in Neuron (Cambridge, Mass.) (22.01.2020)
Published in Neuron (Cambridge, Mass.) (22.01.2020)
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α-Synuclein modulates tau spreading in mouse brains
Bassil, Fares, Meymand, Emily S, Brown, Hannah J, Xu, Hong, Cox, Timothy O, Pattabhiraman, Shankar, Maghames, Chantal M, Wu, Qihui, Zhang, Bin, Trojanowski, John Q, Lee, Virginia M-Y
Published in The Journal of experimental medicine (04.01.2021)
Published in The Journal of experimental medicine (04.01.2021)
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Journal Article
Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology
Bassil, Fares, Brown, Hannah J, Pattabhiraman, Shankar, Iwasyk, Joe E, Maghames, Chantal M, Meymand, Emily S, Cox, Timothy O, Riddle, Dawn M, Zhang, Bin, Trojanowski, John Q, Lee, Virginia M-Y
Published in Neuron (Cambridge, Mass.) (15.11.2023)
Published in Neuron (Cambridge, Mass.) (15.11.2023)
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CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly
Mathiowetz, Alyssa J, Meymand, Emily S, Deol, Kirandeep K, Parlakgül, Güneş, Lange, Mike, Pang, Stephany P, Roberts, Melissa A, Torres, Emily F, Jorgens, Danielle M, Zalpuri, Reena, Kang, Misun, Boone, Casadora, Zhang, Yaohuan, Morgens, David W, Tso, Emily, Zhou, Yingjiang, Talukdar, Saswata, Levine, Tim P, Ku, Gregory, Arruda, Ana Paula, Olzmann, James A
Published in bioRxiv (08.06.2024)
Published in bioRxiv (08.06.2024)
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