DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
Lam, L K Metthew, Murphy, Sophia, Kokkinaki, Dimitra, Venosa, Alessandro, Sherrill-Mix, Scott, Casu, Carla, Rivella, Stefano, Weiner, Aaron, Park, Jeongho, Shin, Sunny, Vaughan, Andrew E, Hahn, Beatrice H, Odom John, Audrey R, Meyer, Nuala J, Hunter, Christopher A, Worthen, G Scott, Mangalmurti, Nilam S
Published in Science translational medicine (20.10.2021)
Published in Science translational medicine (20.10.2021)
Get more information
Journal Article
Multivariate indicators of disease severity in COVID-19
Bean, Joe, Kuri-Cervantes, Leticia, Pennella, Michael, Betts, Michael R., Meyer, Nuala J., Hassan, Wail M.
Published in Scientific reports (29.03.2023)
Published in Scientific reports (29.03.2023)
Get full text
Journal Article
PCSK9 is a critical regulator of the innate immune response and septic shock outcome
Walley, Keith R, Thain, Katherine R, Russell, James A, Reilly, Muredach P, Meyer, Nuala J, Ferguson, Jane F, Christie, Jason D, Nakada, Taka-aki, Fjell, Chris D, Thair, Simone A, Cirstea, Mihai S, Boyd, John H
Published in Science translational medicine (15.10.2014)
Published in Science translational medicine (15.10.2014)
Get more information
Journal Article
Circulating heparan sulfate fragments mediate septic cognitive dysfunction
Hippensteel, Joseph A, Anderson, Brian J, Orfila, James E, McMurtry, Sarah A, Dietz, Robert M, Su, Guowei, Ford, Joshay A, Oshima, Kaori, Yang, Yimu, Zhang, Fuming, Han, Xiaorui, Yu, Yanlei, Liu, Jian, Linhardt, Robert J, Meyer, Nuala J, Herson, Paco S, Schmidt, Eric P
Published in The Journal of clinical investigation (01.04.2019)
Published in The Journal of clinical investigation (01.04.2019)
Get full text
Journal Article
Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome
Merenstein, Carter, Liang, Guanxiang, Whiteside, Samantha A, Cobián-Güemes, Ana G, Merlino, Madeline S, Taylor, Louis J, Glascock, Abigail, Bittinger, Kyle, Tanes, Ceylan, Graham-Wooten, Jevon, Khatib, Layla A, Fitzgerald, Ayannah S, Reddy, Shantan, Baxter, Amy E, Giles, Josephine R, Oldridge, Derek A, Meyer, Nuala J, Wherry, E John, McGinniss, John E, Bushman, Frederic D, Collman, Ronald G
Published in mBio (31.08.2021)
Published in mBio (31.08.2021)
Get full text
Journal Article
Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome
Jones, Tiffanie K, Feng, Rui, Kerchberger, V Eric, Reilly, John P, Anderson, Brian J, Shashaty, Michael G S, Wang, Fan, Dunn, Thomas G, Riley, Thomas R, Abbott, Jason, Ittner, Caroline A G, Christiani, David C, Mikacenic, Carmen, Wurfel, Mark M, Ware, Lorraine B, Calfee, Carolyn S, Matthay, Michael A, Christie, Jason D, Meyer, Nuala J
Published in American journal of respiratory and critical care medicine (01.01.2020)
Published in American journal of respiratory and critical care medicine (01.01.2020)
Get full text
Journal Article
Red blood cells induce necroptosis of lung endothelial cells and increase susceptibility to lung inflammation
Qing, Danielle Y, Conegliano, David, Shashaty, Michael G S, Seo, Jeongyun, Reilly, John P, Worthen, G Scott, Huh, Dongeun, Meyer, Nuala J, Mangalmurti, Nilam S
Published in American journal of respiratory and critical care medicine (01.12.2014)
Published in American journal of respiratory and critical care medicine (01.12.2014)
Get full text
Journal Article
Innate lymphoid cells and COVID-19 severity in SARS-CoV-2 infection
Silverstein, Noah J, Wang, Yetao, Manickas-Hill, Zachary, Carbone, Claudia, Dauphin, Ann, Boribong, Brittany P, Loiselle, Maggie, Davis, Jameson, Leonard, Maureen M, Kuri-Cervantes, Leticia, Meyer, Nuala J, Betts, Michael R, Li, Jonathan Z, Walker, Bruce D, Yu, Xu G, Yonker, Lael M, Luban, Jeremy
Published in eLife (11.03.2022)
Published in eLife (11.03.2022)
Get full text
Journal Article
Tracking gut microbiome and bloodstream infection in critically ill adults
Gu, Christopher H, Khatib, Layla A, Fitzgerald, Ayannah S, Graham-Wooten, Jevon, Ittner, Caroline A, Sherrill-Mix, Scott, Chuang, YuChung, Glaser, Laurel J, Meyer, Nuala J, Bushman, Frederic D, Collman, Ronald G
Published in PloS one (10.10.2023)
Published in PloS one (10.10.2023)
Get full text
Journal Article
Vascular endothelial-derived SPARCL1 exacerbates viral pneumonia through pro-inflammatory macrophage activation
Zhao, Gan, Gentile, Maria E., Xue, Lulu, Cosgriff, Christopher V., Weiner, Aaron I., Adams-Tzivelekidis, Stephanie, Wong, Joanna, Li, Xinyuan, Kass-Gergi, Sara, Holcomb, Nicolas P., Basal, Maria C., Stewart, Kathleen M., Planer, Joseph D., Cantu, Edward, Christie, Jason D., Crespo, Maria M., Mitchell, Michael J., Meyer, Nuala J., Vaughan, Andrew E.
Published in Nature communications (18.05.2024)
Published in Nature communications (18.05.2024)
Get full text
Journal Article
Acute respiratory distress syndrome
Meyer, Nuala J, Gattinoni, Luciano, Calfee, Carolyn S
Published in The Lancet (British edition) (14.08.2021)
Published in The Lancet (British edition) (14.08.2021)
Get full text
Journal Article
Human red blood cells express the RNA sensor TLR7
Metthew Lam, L. K., Oatman, Emily, Eckart, Kaitlyn A., Klingensmith, Nathan J., Flowers, Emily, Sayegh, Layal, Yuen, Julia, Clements, Rebecca L., Meyer, Nuala J., Jurado, Kellie A., Vaughan, Andrew E., Eisenbarth, Stephanie C., Mangalmurti, Nilam S.
Published in Scientific reports (09.07.2024)
Published in Scientific reports (09.07.2024)
Get full text
Journal Article
Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study
Anderson, Brian J, Calfee, Carolyn S, Liu, Kathleen D, Reilly, John P, Kangelaris, Kirsten N, Shashaty, Michael G S, Lazaar, Aili L, Bayliffe, Andrew I, Gallop, Robert J, Miano, Todd A, Dunn, Thomas G, Johansson, Erik, Abbott, Jason, Jauregui, Alejandra, Deiss, Thomas, Vessel, Kathryn, Belzer, Annika, Zhuo, Hanjing, Matthay, Michael A, Meyer, Nuala J, Christie, Jason D
Published in Critical care (London, England) (09.12.2019)
Published in Critical care (London, England) (09.12.2019)
Get full text
Journal Article
Protocol for the MicroRESUS study: The impact of circulatory shock and resuscitation on microcirculatory function and mitochondrial respiration after cardiovascular surgery
Greenwood, John C, Talebi, Fatima M, Jang, David H, Spelde, Audrey E, Kilbaugh, Todd J, Shofer, Frances S, Acker, Michael A, Augoustides, John G. T, Bakker, Jan, Meyer, Nuala J, Brenner, Jacob S, Muzykantov, Vladimir R, Abella, Benjamin S
Published in PloS one (26.08.2022)
Published in PloS one (26.08.2022)
Get full text
Journal Article
Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study
Shashaty, Michael G S, Reilly, John P, Faust, Hilary E, Forker, Caitlin M, Ittner, Caroline A G, Zhang, Peggy X, Hotz, Meghan J, Fitzgerald, David, Yang, Wei, Anderson, Brian J, Holena, Daniel N, Lanken, Paul N, Christie, Jason D, Meyer, Nuala J, Mangalmurti, Nilam S
Published in Critical care (London, England) (28.06.2019)
Published in Critical care (London, England) (28.06.2019)
Get full text
Journal Article
The relationship between vitamin C or thiamine levels and outcomes for severe sepsis patients admitted to the ICU
Prasad, Nandan, Grossestreuer, Anne V., Meyer, Nuala J., Perman, Sarah M., Mikkelsen, Mark E., Hollander, Judd, Gaieski, David F.
Published in Scientific reports (23.07.2021)
Published in Scientific reports (23.07.2021)
Get full text
Journal Article
Admission plasma levels of the neuronal injury marker neuron specific enolase are associated with mortality and delirium in sepsis
Anderson, Brian J., M.D., M.S, Reilly, John P., M.D., M.S, Shashaty, Michael G.S., M.D., M.S, Palakshappa, Jessica A., M.D, Wysoczanski, Alex, Dunn, Thomas G., B.A, Kazi, Altaf, Ph.D, Tommasini, Anna, B.A, Mikkelsen, Mark E., M.D., M.S, Schweickert, William D., M.D, Kolson, Dennis L., M.D., Ph.D, Christie, Jason D., M.D., M.S, Meyer, Nuala J., M.D., M.S
Published in Journal of critical care (01.12.2016)
Published in Journal of critical care (01.12.2016)
Get full text
Journal Article