Ubiquitin profiling of lysophagy identifies actin stabilizer CNN2 as a target of VCP/p97 and uncovers a link to HSPB1
Kravić, Bojana, Bionda, Tihana, Siebert, Alexander, Gahlot, Pinki, Levantovsky, Sophie, Behrends, Christian, Meyer, Hemmo
Published in Molecular cell (21.07.2022)
Published in Molecular cell (21.07.2022)
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Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
RAMADAN, Kristijan, BRUDERER, Roland, SPIGA, Fabio M, POPP, Oliver, BAUR, Tina, GOTTA, Monica, MEYER, Hemmo H
Published in Nature (20.12.2007)
Published in Nature (20.12.2007)
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VCP/p97 Extracts Sterically Trapped Ku70/80 Rings from DNA in Double-Strand Break Repair
van den Boom, Johannes, Wolf, Markus, Weimann, Lena, Schulze, Nina, Li, Fanghua, Kaschani, Farnusch, Riemer, Anne, Zierhut, Christian, Kaiser, Markus, Iliakis, George, Funabiki, Hironori, Meyer, Hemmo
Published in Molecular cell (06.10.2016)
Published in Molecular cell (06.10.2016)
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VCP maintains lysosomal homeostasis and TFEB activity in differentiated skeletal muscle
Arhzaouy, Khalid, Papadopoulos, Chrisovalantis, Schulze, Nina, Pittman, Sara K., Meyer, Hemmo, Weihl, Conrad C.
Published in Autophagy (03.06.2019)
Published in Autophagy (03.06.2019)
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Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly
van den Boom, Johannes, Kueck, Anja F, Kravic, Bojana, Müschenborn, Helen, Giesing, Maike, Pan, Dongqing, Kaschani, Farnusch, Kaiser, Markus, Musacchio, Andrea, Meyer, Hemmo
Published in Nature structural & molecular biology (01.12.2021)
Published in Nature structural & molecular biology (01.12.2021)
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The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
Blueggel, Mike, Kroening, Alexander, Kracht, Matthias, van den Boom, Johannes, Dabisch, Matthias, Goehring, Anna, Kaschani, Farnusch, Kaiser, Markus, Bayer, Peter, Meyer, Hemmo, Beuck, Christine
Published in Nature communications (05.06.2023)
Published in Nature communications (05.06.2023)
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Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations
Weihl, Conrad C, Meyer, Hemmo, Ritz, Danilo, Vuk, Maja, Kirchner, Philipp, Bug, Monika, Schütz, Sabina, Hayer, Arnold, Bremer, Sebastian, Lusk, Caleb, Baloh, Robert H, Lee, Houkeun, Glatter, Timo, Gstaiger, Matthias, Aebersold, Ruedi
Published in Nature cell biology (01.09.2011)
Published in Nature cell biology (01.09.2011)
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Delivery of the autofluorescent protein R-phycoerythrin by calcium phosphate nanoparticles into four different eukaryotic cell lines (HeLa, HEK293T, MG-63, MC3T3): Highly efficient, but leading to endolysosomal proteolysis in HeLa and MC3T3 cells
Kopp, Mathis, Rotan, Olga, Papadopoulos, Chrisovalantis, Schulze, Nina, Meyer, Hemmo, Epple, Matthias
Published in PloS one (06.06.2017)
Published in PloS one (06.06.2017)
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AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation
Hülsmann, Julia, Kravic, Bojana, Weith, Matthias, Gstaiger, Matthias, Aebersold, Ruedi, Collins, Ben C., Meyer, Hemmo
Published in Molecular & cellular proteomics (01.07.2018)
Published in Molecular & cellular proteomics (01.07.2018)
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VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, Blanca, Typas, Dimitris, van den Boom, Johannes, Benedict, Bente, Hendriks, Ivo A, Nielsen, Michael Lund, Meyer, Hemmo, Duxin, Julien P, Montoya, Guillermo, Mailand, Niels
Published in Nature communications (19.03.2024)
Published in Nature communications (19.03.2024)
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