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Effects of vitamin K 2 combined with methotrexate against mitogen‐activated peripheral blood mononuclear cells of healthy subjects and rheumatoid arthritis patients
Xu, Wencheng, Wu, Hongguang, Tahara, Koichiro, Chen, Shuhe, Wang, Xiaoqin, Tanaka, Sachiko, Sugiyama, Kentaro, Sawada, Tetsuji, Hirano, Toshihiko
Published in Fundamental & clinical pharmacology (01.10.2021)
Published in Fundamental & clinical pharmacology (01.10.2021)
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Methotrexate polyglutamates
Yang, Zhilin, Mo, Jiayi, Li, Wenshu, Zhao, Zhigang, Mei, Shenghui
Published in Expert review of clinical pharmacology (01.11.2024)
Published in Expert review of clinical pharmacology (01.11.2024)
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AB0727 A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PARALLEL GROUP STUDY TO EVALUATE THE EFFICACY OF METHOTREXATE AS REMISSION MAINTENANCE THERAPY AFTER REMISSION-INDUCTION THERAPY WITH TOCILIZUMAB AND GLUCOCORTICOIDS IN SUBJECTS WITH GIANT CELL ARTERITIS (METEORITICS TRIAL): STUDY PROTOCOL
Kreis, L., Schmidt, W. A., Venhoff, N., Dejaco, C., Schäfer, V.
Published in Annals of the rheumatic diseases (01.06.2023)
Published in Annals of the rheumatic diseases (01.06.2023)
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Histidine catabolism is a major determinant of methotrexate sensitivity
Kanarek, Naama, Keys, Heather R., Cantor, Jason R., Lewis, Caroline A., Chan, Sze Ham, Kunchok, Tenzin, Abu-Remaileh, Monther, Freinkman, Elizaveta, Schweitzer, Lawrence D., Sabatini, David M.
Published in Nature (London) (01.07.2018)
Published in Nature (London) (01.07.2018)
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POS0624 EFFICACY AND SAFETY OF LEVILIMAB IN COMBINATION WITH METHOTREXATE IN SUBJECTS WITH ACTIVE RHEUMATOID ARTHRITIS: PHASE III, DOUBLE-BLIND, PLACEBO-CONTROLLED, RANDOMIZED TRIAL
Mazurov, V., Korolev, M., Kundzer, A., Soroka, N., Kastanayan, A., Povarova, T., Plaksina, T., Antipova, O., Kretchikova, D., Smakotina, S., Tciupa, O., Raskina, T., Kropotina, T., Nesmeyanova, O., Popova, T., Dokukina, E., Plotnikova, A., Lutskii, A., Zinkina-Orihan, A.
Published in Annals of the rheumatic diseases (01.06.2021)
Published in Annals of the rheumatic diseases (01.06.2021)
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Methotrexate hampers immunogenicity to BNT162b2 mRNA COVID-19 vaccine in immune-mediated inflammatory disease
Haberman, Rebecca H, Herati, Ramin, Simon, David, Samanovic, Marie, Blank, Rebecca B, Tuen, Michael, Koralov, Sergei B, Atreya, Raja, Tascilar, Koray, Allen, Joseph R, Castillo, Rochelle, Cornelius, Amber R, Rackoff, Paula, Solomon, Gary, Adhikari, Samrachana, Azar, Natalie, Rosenthal, Pamela, Izmirly, Peter, Samuels, Jonathan, Golden, Brian, Reddy, Soumya M, Neurath, Markus F, Abramson, Steven B, Schett, Georg, Mulligan, Mark J, Scher, Jose U
Published in Annals of the rheumatic diseases (01.10.2021)
Published in Annals of the rheumatic diseases (01.10.2021)
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A study to evaluate the safety, tolerability, and efficacy of brodalumab in subjects with rheumatoid arthritis and an inadequate response to methotrexate
Pavelka, Karel, Chon, Yun, Newmark, Richard, Lin, Shao-Lee, Baumgartner, Scott, Erondu, Ngozi
Published in Journal of rheumatology (01.06.2015)
Published in Journal of rheumatology (01.06.2015)
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Atacicept in patients with rheumatoid arthritis and an inadequate response to methotrexate: Results of a phase II, randomized, placebo‐controlled trial
van Vollenhoven, R. F., Kinnman, N., Vincent, E., Wax, S., Bathon, J.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2011)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.07.2011)
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Effects of vitamin K2 combined with methotrexate against mitogen‐activated peripheral blood mononuclear cells of healthy subjects and rheumatoid arthritis patients
Xu, Wencheng, Wu, Hongguang, Tahara, Koichiro, Chen, Shuhe, Wang, Xiaoqin, Tanaka, Sachiko, Sugiyama, Kentaro, Sawada, Tetsuji, Hirano, Toshihiko
Published in Fundamental & clinical pharmacology (01.10.2021)
Published in Fundamental & clinical pharmacology (01.10.2021)
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Olokizumab, a monoclonal antibody against interleukin 6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by methotrexate: efficacy and safety results of a randomised controlled phase III study
Nasonov, Evgeniy, Fatenejad, Saeed, Feist, Eugen, Ivanova, Mariana, Korneva, Elena, Krechikova, Diana G, Maslyanskiy, Aleksey L, Samsonov, Mikhail, Stoilov, Rumen, Zonova, Elena V, Genovese, Mark
Published in Annals of the rheumatic diseases (01.04.2022)
Published in Annals of the rheumatic diseases (01.04.2022)
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Effect of SLCO1B1 Polymorphisms on High‐Dose Methotrexate Clearance in Children and Young Adults With Leukemia and Lymphoblastic Lymphoma
Schulte, Rachael R., Choi, Leena, Utreja, Nipun, Van Driest, Sara L., Stein, C. Michael, Ho, Richard H.
Published in Clinical and translational science (01.01.2021)
Published in Clinical and translational science (01.01.2021)
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A randomized comparative effectiveness study of oral triple therapy versus etanercept plus methotrexate in early aggressive rheumatoid arthritis: The Treatment of Early Aggressive Rheumatoid Arthritis trial
Moreland, Larry W., O'Dell, James R., Paulus, Harold E., Curtis, Jeffrey R., Bathon, Joan M., St.Clair, E. William, Bridges Jr, S. Louis, Zhang, Jie, McVie, Theresa, Howard, George, van der Heijde, Désirée, Cofield, Stacey S.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2012)
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Transport of methotrexate, methotrexate polyglutamates, and 17β-estradiol 17-(β-D-glucuronide) by ABCG2: Effects of acquired mutations at R482 on methotrexate transport
CHEN, Zhe-Sheng, ROBEY, Robert W, BELINSKY, Martin G, SHCHAVELEVA, Irina, REN, Xiao-Qin, SUGIMOTO, Yoshikazu, ROSS, Douglas D, BATES, Susan E, KRUH, Gary D
Published in Cancer research (Chicago, Ill.) (15.07.2003)
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Published in Cancer research (Chicago, Ill.) (15.07.2003)
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Reanalysis of the Multi‐Biomarker Disease Activity Score for Assessing Disease Activity in the Abatacept Versus Adalimumab Comparison in Biologic‐Naive Rheumatoid Arthritis Subjects with Background Methotrexate Study: Comment on the Article by Fleischmann et al
Curtis, Jeffrey R., Wright, Grace C., Strand, Vibeke, Davis, Charles S., Hitraya, Elena, Sasso, Eric H.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2017)
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POS1136 PHARMACOKINETICS OF PEGLOTICASE AND METHOTREXATE POLYGLUTAMATE(S) IN PATIENTS WITH UNCONTROLLED GOUT RECEIVING PEGLOTICASE AND CO-TREATMENT OF METHOTREXATE
Song, Y., Xin, Y., Weinblatt, M.E., Chamberlain, J., Obermeyer, K., Zhao, L., Canavan, C., Peloso, P.M., Ramanathan, S.
Published in Annals of the rheumatic diseases (01.06.2021)
Published in Annals of the rheumatic diseases (01.06.2021)
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Co‐prescription of low‐dose methotrexate and trimethoprim‐sulfamethoxazole and the 30‐day risk of death among older adults: A cohort study
Sadeghi, Hasti, Ahmadi, Fatemeh, McArthur, Eric, Sontrop, Jessica M., Abdullah, Sheikh S., Urquhart, Brad L., Kim, Richard B., Muanda, Flory T.
Published in British journal of clinical pharmacology (01.04.2025)
Published in British journal of clinical pharmacology (01.04.2025)
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Co‐administration of proton pump inhibitors delays elimination of plasma methotrexate in high‐dose methotrexate therapy
Suzuki, Kunihiro, Doki, Kosuke, Homma, Masato, Tamaki, Hirofumi, Hori, Satoko, Ohtani, Hisakazu, Sawada, Yasufumi, Kohda, Yukinao
Published in British journal of clinical pharmacology (01.01.2009)
Published in British journal of clinical pharmacology (01.01.2009)
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POS0287 A PHASE III, RANDOMISED, DOUBLE-BLIND, ACTIVE-CONTROLLED CLINICAL TRIAL TO COMPARE BAT1806/BIIB800, A PROPOSED TOCILIZUMAB BIOSIMILAR, WITH TOCILIZUMAB REFERENCE PRODUCT IN SUBJECTS WITH MODERATE TO SEVERE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATE THERAPY
Leng, X., Leszczynski, P., Jeka, S., Liu, S., Liu, H., Miakisz, M., Gu, J., Kilasonia, L., Stanislavchuk, M., Yang, X., Zhou, Y., Dong, Q., Mitroiu, M., Addison, J., Zeng, X.
Published in Annals of the rheumatic diseases (01.06.2022)
Published in Annals of the rheumatic diseases (01.06.2022)
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SAT0183 Clinical remission in subjects with rheumatoid arthritis treated with subcutaneous tocilizumab as monotherapy or in combination with methotrexate or other synthetic dmards: a real-world clinical trial (tospace)
Sanmarti, R, Mola, E Martín, Fonseca, JE, Veale, DJ, Escudero, A, González, C
Published in Annals of the rheumatic diseases (01.06.2017)
Published in Annals of the rheumatic diseases (01.06.2017)
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