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Validation of 4β‐hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects
Kasichayanula, Sreeneeranj, Boulton, David W., Luo, Wen‐Lin, Rodrigues, A. David, Yang, Zheng, Goodenough, Angela, Lee, Michelle, Jemal, Mohammed, LaCreta, Frank
Published in British journal of clinical pharmacology (01.11.2014)
Published in British journal of clinical pharmacology (01.11.2014)
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A safety grading scale to support dose escalation and define stopping rules for healthy subject first-entry-into-man studies: Some points to consider from the French Club Phase I
Sibille, Michel, Patat, Alain, Caplain, Henri, Donazzolo, Yves
Published in British journal of clinical pharmacology (01.11.2010)
Published in British journal of clinical pharmacology (01.11.2010)
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Microdialysis as a tool to determine the local tissue concentration of dicloxacillin in man
Hansen, Kristian Kraft, Nielsen, Flemming, Stage, Tore Bjerregaard, Jørgensen, Uffe, Skov, Ole, Rasmussen, Lasse E.
Published in British journal of clinical pharmacology (01.03.2018)
Published in British journal of clinical pharmacology (01.03.2018)
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Impact of source data verification on data quality in clinical trials: an empirical post hoc analysis of three phase 3 randomized clinical trials
Andersen, Jeppe Ragnar, Byrjalsen, Inger, Bihlet, Asger, Kalakou, Faidra, Hoeck, Hans Christian, Hansen, Gitte, Hansen, Henrik Bo, Karsdal, Morten Asser, Riis, Bente Juel
Published in British journal of clinical pharmacology (01.04.2015)
Published in British journal of clinical pharmacology (01.04.2015)
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The impact of CYP3A53 polymorphism on sirolimus pharmacokinetics: insights from predictions with a physiologically‐based pharmacokinetic model
Emoto, Chie, Fukuda, Tsuyoshi, Venkatasubramanian, Raja, Vinks, Alexander A.
Published in British journal of clinical pharmacology (01.12.2015)
Published in British journal of clinical pharmacology (01.12.2015)
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Development of an in vivo target‐engagement biomarker for TRPA1 antagonists in humans
Buntinx, Linde, Chang, Lin, Amin, Aasim, Morlion, Bart, Hoon, Jan
Published in British journal of clinical pharmacology (01.03.2017)
Published in British journal of clinical pharmacology (01.03.2017)
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The use of plethysmography and oscillometry to compare long‐acting bronchodilators in patients with COPD
Borrill, Zoë L., Houghton, Catherine M., Tal‐Singer, Ruth, Vessey, S Rupert, Faiferman, Isidore, Langley, Stephen J., Singh, Dave
Published in British journal of clinical pharmacology (01.02.2008)
Published in British journal of clinical pharmacology (01.02.2008)
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Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index
Jiang, Fen, Desta, Zeruesenay, Shon, Ji‐Hong, Yeo, Chang‐Woo, Kim, Ho‐Sook, Liu, Kwang‐Hyeon, Bae, Soo‐Kyung, Lee, Sang‐Seop, Flockhart, David A., Shin, Jae‐Gook
Published in British journal of clinical pharmacology (01.01.2013)
Published in British journal of clinical pharmacology (01.01.2013)
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Bayesian adaptive designs in single ascending dose trials in healthy volunteers
Guédé, David, Reigner, Bruno, Vandenhende, Francois, Derks, Mike, Beyer, Ulrich, Jordan, Paul, Worth, Eric, Diack, Cheikh, Frey, Nicolas, Peck, Richard
Published in British journal of clinical pharmacology (01.08.2014)
Published in British journal of clinical pharmacology (01.08.2014)
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Levofloxacin can be used effectively as a positive control in thorough QT/QTc studies in healthy volunteers
Taubel, Jorg, Naseem, Asif, Harada, Tomohiko, Wang, Duolao, Arezina, Radivoj, Lorch, Ulrike, Camm, A John
Published in British journal of clinical pharmacology (01.04.2010)
Published in British journal of clinical pharmacology (01.04.2010)
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An efficient approach for glomerular filtration rate assessment in older adults
Martus, Peter, Ebert, Natalie, Giet, Markus, Jakob, Olga, Schaeffner, Elke S.
Published in British journal of clinical pharmacology (01.08.2014)
Published in British journal of clinical pharmacology (01.08.2014)
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Use of Entero‐Test, a simple approach for non‐invasive clinical evaluation of the biliary disposition of drugs
Guiney, William J., Beaumont, Claire, Thomas, Steve R., Robertson, Darren C., McHugh, Simon M., Koch, Annelize, Richards, Duncan
Published in British journal of clinical pharmacology (01.07.2011)
Published in British journal of clinical pharmacology (01.07.2011)
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Not‐in‐trial simulation I: Bridging cardiovascular risk from clinical trials to real‐life conditions
Chain, Anne S. Y., Dieleman, Jeanne P., Noord, Charlotte, Hofman, Albert, Stricker, Bruno H. Ch, Danhof, Meindert, Sturkenboom, Miriam C. J. M., Della Pasqua, Oscar
Published in British journal of clinical pharmacology (01.12.2013)
Published in British journal of clinical pharmacology (01.12.2013)
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Quantification of the spatial distribution of rectally applied surrogates for microbicide and semen in colon with SPECT and magnetic resonance imaging
Cao, Ying J., Caffo, Brian S., Fuchs, Edward J., Lee, Linda A., Du, Yong, Li, Liye, Bakshi, Rahul P., Macura, Katarzyna, Khan, Wasif A., Wahl, Richard L., Grohskopf, Lisa A., Hendrix, Craig W.
Published in British journal of clinical pharmacology (01.12.2012)
Published in British journal of clinical pharmacology (01.12.2012)
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Informed consent document improvement does not increase patients' comprehension in biomedical research
Paris, Adeline, Brandt, Christian, Cornu, Catherine, Maison, Patrick, Thalamas, Claire, Cracowski, Jean‐Luc
Published in British journal of clinical pharmacology (01.03.2010)
Published in British journal of clinical pharmacology (01.03.2010)
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