High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa
Corral-Lugo, Andrés, Matilla, Miguel A, Martín-Mora, David, Silva Jiménez, Hortencia, Mesa Torres, Noel, Kato, Junichi, Hida, Akiko, Oku, Shota, Conejero-Muriel, Mayte, Gavira, Jose A, Krell, Tino
Published in mBio (13.11.2018)
Published in mBio (13.11.2018)
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Journal Article
Determination of Ligand Profiles for Pseudomonas aeruginosa Solute Binding Proteins
Fernández, Matilde, Rico-Jiménez, Miriam, Ortega, Álvaro, Daddaoua, Abdelali, García García, Ana Isabel, Martín-Mora, David, Torres, Noel Mesa, Tajuelo, Ana, Matilla, Miguel A, Krell, Tino
Published in International journal of molecular sciences (17.10.2019)
Published in International journal of molecular sciences (17.10.2019)
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Journal Article
Conformational dynamics is key to understanding loss-of-function of NQO1 cancer-associated polymorphisms and its correction by pharmacological ligands
Medina-Carmona, Encarnación, Palomino-Morales, Rogelio J., Fuchs, Julian E., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Salido, Eduardo, Timson, David J., Pey, Angel L.
Published in Scientific reports (03.02.2016)
Published in Scientific reports (03.02.2016)
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Journal Article
Improving the Activity and Stability of Human Galactokinase for Therapeutic and Biotechnological Applications
McAuley, Margaret, Mesa‐Torres, Noel, McFall, Aisling, Morris, Sarah, Huang, Meilan, Pey, Angel L., Timson, David J.
Published in Chembiochem : a European journal of chemical biology (18.05.2018)
Published in Chembiochem : a European journal of chemical biology (18.05.2018)
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Journal Article
NQO1: A target for the treatment of cancer and neurological diseases, and a model to understand loss of function disease mechanisms
Beaver, Sarah K., Mesa-Torres, Noel, Pey, Angel L., Timson, David J.
Published in Biochimica et biophysica acta. Proteins and proteomics (01.07.2019)
Published in Biochimica et biophysica acta. Proteins and proteomics (01.07.2019)
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Journal Article
Phosphorylation of Thr9 Affects the Folding Landscape of the N-Terminal Segment of Human AGT Enhancing Protein Aggregation of Disease-Causing Mutants
Neira, Jose L, Naganathan, Athi N, Mesa-Torres, Noel, Salido, Eduardo, Pey, Angel L
Published in Molecules (Basel, Switzerland) (10.12.2022)
Published in Molecules (Basel, Switzerland) (10.12.2022)
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Journal Article
A single evolutionarily divergent mutation determines the different FAD‐binding affinities of human and rat NQO1 due to site‐specific phosphorylation
Pacheco‐Garcia, Juan Luis, Loginov, Dmitry, Rizzuti, Bruno, Vankova, Pavla, Neira, Jose L., Kavan, Daniel, Mesa‐Torres, Noel, Guzzi, Rita, Man, Petr, Pey, Angel L.
Published in FEBS letters (01.01.2022)
Published in FEBS letters (01.01.2022)
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Journal Article
The lower limits for protein stability and foldability in primary hyperoxaluria type I
Mesa-Torres, Noel, Salido, Eduardo, Pey, Angel L.
Published in Biochimica et biophysica acta (01.12.2014)
Published in Biochimica et biophysica acta (01.12.2014)
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Journal Article
Structural basis of the pleiotropic and specific phenotypic consequences of missense mutations in the multifunctional NAD(P)H:quinone oxidoreductase 1 and their pharmacological rescue
Pacheco-Garcia, Juan Luis, Anoz-Carbonell, Ernesto, Vankova, Pavla, Kannan, Adithi, Palomino-Morales, Rogelio, Mesa-Torres, Noel, Salido, Eduardo, Man, Petr, Medina, Milagros, Naganathan, Athi N., Pey, Angel L.
Published in Redox biology (01.10.2021)
Published in Redox biology (01.10.2021)
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Journal Article
The role of protein denaturation energetics and molecular chaperones in the aggregation and mistargeting of mutants causing primary hyperoxaluria type I
Mesa-Torres, Noel, Fabelo-Rosa, Israel, Riverol, Debora, Yunta, Cristina, Albert, Armando, Salido, Eduardo, Pey, Angel L
Published in PloS one (27.08.2013)
Published in PloS one (27.08.2013)
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Journal Article
The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine-glyoxylate aminotransferase
Mesa-Torres, Noel, Yunta, Cristina, Fabelo-Rosa, Israel, Gonzalez-Rubio, Juana María, Sánchez-Ruiz, José M, Salido, Eduardo, Albert, Armando, Pey, Angel L
Published in Biochemical journal (15.09.2014)
Published in Biochemical journal (15.09.2014)
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Journal Article
Insight into the specificity and severity of pathogenic mechanisms associated with missense mutations through experimental and structural perturbation analyses
Medina-Carmona, Encarnación, Betancor-Fernández, Isabel, Santos, Jaime, Mesa-Torres, Noel, Grottelli, Silvia, Batlle, Cristina, Naganathan, Athi N, Oppici, Elisa, Cellini, Barbara, Ventura, Salvador, Salido, Eduardo, Pey, Angel L
Published in Human molecular genetics (01.01.2019)
Published in Human molecular genetics (01.01.2019)
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Journal Article
Enhanced vulnerability of human proteins towards disease-associated inactivation through divergent evolution
Medina-Carmona, Encarnación, Fuchs, Julian E, Gavira, Jose A, Mesa-Torres, Noel, Neira, Jose L, Salido, Eduardo, Palomino-Morales, Rogelio, Burgos, Miguel, Timson, David J, Pey, Angel L
Published in Human molecular genetics (15.09.2017)
Published in Human molecular genetics (15.09.2017)
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Journal Article
The metastability of human UDP-galactose 4′-epimerase (GALE) is increased by variants associated with type III galactosemia but decreased by substrate and cofactor binding
Pey, Angel L., Padín-Gonzalez, Esperanza, Mesa-Torres, Noel, Timson, David J.
Published in Archives of biochemistry and biophysics (15.11.2014)
Published in Archives of biochemistry and biophysics (15.11.2014)
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Journal Article
Phosphorylation compromises FAD binding and intracellular stability of wild-type and cancer-associated NQO1: Insights into flavo-proteome stability
Medina-Carmona, Encarnación, Rizzuti, Bruno, Martín-Escolano, Rubén, Pacheco-García, Juan Luis, Mesa-Torres, Noel, Neira, José L., Guzzi, Rita, Pey, Angel L.
Published in International journal of biological macromolecules (15.03.2019)
Published in International journal of biological macromolecules (15.03.2019)
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Journal Article
Evolutionary Divergent Suppressor Mutations in Conformational Diseases
Mesa-Torres, Noel, Betancor-Fernández, Isabel, Oppici, Elisa, Cellini, Barbara, Salido, Eduardo, Pey, Angel L
Published in Genes (13.07.2018)
Published in Genes (13.07.2018)
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Journal Article
Structural and functional insights on the roles of molecular chaperones in the mistargeting and aggregation phenotypes associated with primary hyperoxaluria type I
Fernández-Higuero, José Ángel, Betancor-Fernández, Isabel, Mesa-Torres, Noel, Muga, Arturo, Salido, Eduardo, Pey, Angel L
Published in Advances in protein chemistry and structural biology (2019)
Published in Advances in protein chemistry and structural biology (2019)
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Journal Article
Caenorhabditis elegans AGXT-1 is a mitochondrial and temperature-adapted ortholog of peroxisomal human AGT1: New insights into between-species divergence in glyoxylate metabolism
Mesa-Torres, Noel, Calvo, Ana C., Oppici, Elisa, Titelbaum, Nicholas, Montioli, Riccardo, Miranda-Vizuete, Antonio, Cellini, Barbara, Salido, Eduardo, Pey, Angel L.
Published in Biochimica et biophysica acta (01.09.2016)
Published in Biochimica et biophysica acta (01.09.2016)
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