The role of ubiquitination in spinal and bulbar muscular atrophy
Sengupta, Medha, Pluciennik, Anna, Merry, Diane E
Published in Frontiers in molecular neuroscience (06.10.2022)
Published in Frontiers in molecular neuroscience (06.10.2022)
Get full text
Journal Article
Activation of Hsp70 reduces neurotoxicity by promoting polyglutamine protein degradation
Wang, Adrienne M, Miyata, Yoshinari, Klinedinst, Susan, Peng, Hwei-Ming, Chua, Jason P, Komiyama, Tomoko, Li, Xiaokai, Morishima, Yoshihiro, Merry, Diane E, Pratt, William B, Osawa, Yoichi, Collins, Catherine A, Gestwicki, Jason E, Lieberman, Andrew P
Published in Nature chemical biology (01.02.2013)
Published in Nature chemical biology (01.02.2013)
Get full text
Journal Article
Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA
Zboray, Lori, Pluciennik, Anna, Curtis, Dana, Liu, Yuhong, Berman-Booty, Lisa D., Orr, Christopher, Kesler, Cristina T., Berger, Tamar, Gioeli, Daniel, Paschal, Bryce M., Merry, Diane E.
Published in Cell reports (Cambridge) (15.12.2015)
Published in Cell reports (Cambridge) (15.12.2015)
Get full text
Journal Article
Cytoplasmic retention of polyglutamine-expanded androgen receptor ameliorates disease via autophagy in a mouse model of spinal and bulbar muscular atrophy
Montie, Heather L., Cho, Maria S., Holder, Latia, Liu, Yuhong, Tsvetkov, Andrey S., Finkbeiner, Steven, Merry, Diane E.
Published in Human molecular genetics (01.06.2009)
Published in Human molecular genetics (01.06.2009)
Get full text
Journal Article
Disrupting SUMOylation enhances transcriptional function and ameliorates polyglutamine androgen receptor-mediated disease
Chua, Jason P, Reddy, Satya L, Yu, Zhigang, Giorgetti, Elisa, Montie, Heather L, Mukherjee, Sarmistha, Higgins, Jake, McEachin, Richard C, Robins, Diane M, Merry, Diane E, Iñiguez-Lluhí, Jorge A, Lieberman, Andrew P
Published in The Journal of clinical investigation (01.02.2015)
Published in The Journal of clinical investigation (01.02.2015)
Get full text
Journal Article
An Interdomain Interaction of the Androgen Receptor Is Required for Its Aggregation and Toxicity in Spinal and Bulbar Muscular Atrophy
Orr, Christopher R., Montie, Heather L., Liu, Yuhong, Bolzoni, Elena, Jenkins, Shannon C., Wilson, Elizabeth M., Joseph, James D., McDonnell, Donald P., Merry, Diane E.
Published in The Journal of biological chemistry (12.11.2010)
Published in The Journal of biological chemistry (12.11.2010)
Get full text
Journal Article
Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice
Garcia Castro, David R., Mazuk, Joseph R., Heine, Erin M., Simpson, Daniel, Pinches, R. Seth, Lozzi, Caroline, Hoffman, Kathryn, Morrin, Phillip, Mathis, Dylan, Lebedev, Maria V., Nissley, Elyse, Han, Kang Hoo, Farmer, Tyler, Merry, Diane E., Tong, Qiang, Pennuto, Maria, Montie, Heather L.
Published in iScience (18.08.2023)
Published in iScience (18.08.2023)
Get full text
Journal Article
Castration Restores Function and Neurofilament Alterations of Aged Symptomatic Males in a Transgenic Mouse Model of Spinal and Bulbar Muscular Atrophy
Chevalier-Larsen, Erica S, O'Brien, Christopher J, Wang, Huiyi, Jenkins, Shannon C, Holder, Latia, Lieberman, Andrew P, Merry, Diane E
Published in The Journal of neuroscience (19.05.2004)
Published in The Journal of neuroscience (19.05.2004)
Get full text
Journal Article
The 11S Proteasomal Activator REGγ Impacts Polyglutamine-Expanded Androgen Receptor Aggregation and Motor Neuron Viability through Distinct Mechanisms
Yersak, Jill M, Montie, Heather L, Chevalier-Larsen, Erica S, Liu, Yuhong, Huang, Lan, Rechsteiner, Martin, Merry, Diane E
Published in Frontiers in molecular neuroscience (24.05.2017)
Published in Frontiers in molecular neuroscience (24.05.2017)
Get full text
Journal Article
Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy
Arnold, Frederick J., Pluciennik, Anna, Merry, Diane E.
Published in Scientific reports (15.01.2019)
Published in Scientific reports (15.01.2019)
Get full text
Journal Article